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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Healing of duodenal ulcer after eradication of Helicobacter heilmannii显示文摘 | Andrew F Goddard Robert PH Logan John C Atherton David Jenkins Robin C Spiller | 1997 | The Lancet1997，，9068： | 2 |
| 3 | Forest litter production,chemistry,and decomposition following two years of free air CO2 enrichment显示文摘 | ADRIEN C F ANDREW S A EVAN H D | 2001 | Ecology2001，82，2： | 1 |
| 4 | Floral dip:a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana显示文摘 | Steven J C Andrew F B | 1998 | Plant J1998，16，6： | 1 |
| 5 | Soluble intedeukin6 receptor ( slL -6R) mediates colonic tumor cell adherence to thevascular endothe- lium:a mechanism for metastatic initiation 显示文摘 | Dowdall J F Winter D C Andrews E | 2002 | J Surg Res2002，107，1： | 1 |
| 6 | Groundwater sampling and analysis:A field guide显示文摘 | Baskaran S Andrew J F Patrice D C | 2009 | Geoscience Austral-ia2009，27，： | 1 |
| 7 | Changes in laG stable isotopes in mul- tiple tissues of insect predators fed isotopically distinct prey显示文摘 | Gratton C Andrew E F | 2006 | Oecologia2006，147，4： | 1 |
| 8 | Rational dosing of antimicrobial a- gents : Phaimacokinetie and pharmaeodynamic strategies 显示文摘 | Robert C Owens Jr Andrew F | 2009 | Heahh-Syst Pharm2009，66，4： | 1 |
| 9 | Ablative Fractional Laser Resurfacing Helps Treat Restrictive Pediatric Scar Contraemres显示文摘 | Andrew C Alina Lawrence F | 2014 | Pediatrics2014，134，： | 1 |
| 10 | Tissue kinetics of telithromycin, the first ketolide antibacterial 显示文摘 | Muller-Serieys C Andrews J Vacheron F | 2004 | J Antimicrob Chemother2004，53，2： | 1 |
| 11 | Acceleration of the discrete element method (DEM) on a reconfigurable co-processor 显示文摘 | BENJAMIN C S STEVEN F Q ANDREW H C C | 2004 | Computers and Structures2004，82，2021： | 1 |
| 12 | Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis 显示文摘 | McCann F E Palfreeman A C Andrews M | 2010 | Arthritis Res Ther2010，12，3： | 1 |
| 13 | Bacte- rial iron homeostasis 显示文摘 | Andrews S C Robinson A K Rodriguez-Quifiones F | 2003 | Ferns Micro-biol2003，，27： | 1 |
| 14 | L- and M-shell X-ray production cross section of Nd, Gd, Ho, Yb, Au, and Pb by 25 MeV carbon and 32 MeVoxygenions显示文摘 | ANDREWS M C MCDANIEL F D | 1987 | PhysRevA1987，36，： | 1 |
| 15 | Muhifactorial refractory heterotopic ossification 显示文摘 | Gear Andrew JL Buckley C K aplan F | 2004 | Annals of Plastic Surgery2004，52，3： | 1 |
| 16 | Simple genetic algorithm search for critical noncircular failure surface in slope stability analysis显示文摘 | ALl R Z ANDREW C H PAUL F M | 2005 | Computers and Geoteehuies2005，32，3： | 1 |
| 17 | A comparison of parathyroid hormone‐related protein (1‐36) and parathyroid hormone (1‐34) on markers of bone turnover and bone density in postmenopausal women: The PrOP study显示文摘 | Mara J Horwitz Marilyn Augustine Leila Kahn Emily Martin Christine C Oakley Raquel M Carneiro Mary Beth Tedesco Angela Laslavic Susan M Sereika Alessandro Bisello Adolfo Garcia‐Oca?a Caren M Gundberg Jane A Cauley Andrew F Stewart | 2013 | J Bone Miner Res2013，，11： | 1 |
| 18 | Ytterbium trifluoromethanesulfonate as a novel catalyst for the allylation of aldehydes 显示文摘 | HELEN C A ANDREW F B NICHOLAS G | 1994 | Tetrahedron Letters1994，35，26： | 1 |
| 19 | Infection, multiple organ failure, and survival in the intensive care unit: influence of glutamine-supplemented parenteral nutrition on acquired infection 显示文摘 | Grifllths RD Allen KD Andrews F J Jones C | 2002 | Nutrition2002，18，78： | 1 |
| 20 | The effects of stilbestrol and testosterone on the gro~h and fattening of lambs显示文摘 | ANDREWS F N BEESON W M HARPER C | 1949 | J Anim Sci1949，8，： | 1 |
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