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| 1 | Novel biomarkers for patient stratification in colorectal cancer:A review of definitions,emerging concepts,and data显示文摘Colorectal cancer(CRC) treatment has become more personalised,incorporating a combination of the individual patient risk assessment,gene testing,and chemotherapy with surgery for optimal care.The improvement of staging with high-resolution imaging has allowed more selective treatments,optimising survival outcomes.The next step is to identify biomarkers that can inform clinicians of expected prognosis and offer the most beneficial treatment,while reducing unnecessary morbidity for the patient.The search for biomarkers in CRC has been of significant interest,with questions remaining on their impact and applicability.The study of biomarkers can be broadly divided into metabolic,molecular,micro RNA,epithelial-to-mesenchymal-transition(EMT),and imaging classes.Although numerous molecules have claimed to impact prognosis and treatment,their clinical application has been limited.Furthermore,routine testing of prognostic markers with no demonstrable influence on response to treatment is a questionable practice,as it increases cost and can adversely affect expectations of treatment.In this review we focus on recent developments and emerging biomarkers with potential utility for clinical translation in CRC.We examine and critically appraise novel imaging and molecular-based approaches; evaluate the promising array of micro RNAs,analyze metabolic profiles,and highlight key findings for biomarker potential in the EMT pathway. | Manish Chand Deborah S Keller Reza Mirnezami Marc Bullock Aneel Bhangu Brendan Moran Paris P Tekkis Gina Brown Alex Mirnezami Mariana Berho | 2018 | World Journal of Gastrointestinal Oncology2018，10，7： | 2 |
| 2 | Neonatal and 5-year outcomes after birth at 30-34 weeks of gestation 显示文摘 | Marret S Aneel PY Marpean L | 2007 | Obstet Gynecol2007，110，1： | 1 |
| 3 | Postoperative Nonsteroidal Anti-inflammatory Drugs and Risk of Anastomotic Leak: Meta-analysis of Clinical and Experimental Studies显示文摘 | Aneel Bhangu Prashant Singh J. Edward F. Fitzgerald Alistair Slesser Paris Tekkis | 2014 | World Journal of Surgery2014，，： | 1 |
| 4 | Laminar Fluid Behavior in Micro-Channels Using Micropolar Fluid Theory显示文摘 | Papautsky I Brazzle J Aneel T | | 0，，： | 1 |
| 5 | Risk of site-specific cancer in incident venous thromboembolism: A population-based study显示文摘 | Tanya M. Petterson Randolph S. Marks Aneel A. Ashrani Kent R. Bailey John A. Heit | 2014 | Thrombosis Research2014，，： | 1 |
| 6 | Cerebral Palsy Among Very Preterm Children in Relation to Gestational Age and Neonatal Ultrasound Abnormalities: The EPIPAGE Cohort Study显示文摘 | Pierre- Yves Aneel Florence Livinec B atrice Larroque | 2006 | Pediatrics2006，3，117： | 1 |
| 7 | Neonatal and 5-year outcomes after birth at 30-34 weeks of gestation显示文摘 | Marret S Aneel PY Marpean L | 2007 | Obstet Gynecol2007，110，1： | 1 |
| 8 | Survival Outcome of Local Excision Versus Radical Resection of Colon or Rectal Carcinoma显示文摘 | Aneel B Gina B John W | 2013 | Ann Surg2013，00，： | 1 |
| 9 | Selection of suitable site in Pakistan for wind power plant installation using analytic hierarchy process(AHP)显示文摘Rise in environmental pollution is a critical problem faced by mankind today.Many interventions have been made to reduce the carbon emissions and other greenhouse gases.Interventions,such as the introduction of electric cars,and innovative techniques to harness energy from renewable sources have been implemented.Pakistan is also very focused on exploiting its renewable energy sources and many sources have been identified.Wind energy is considered to have a promising potential and numerous sites have been identified for installation of wind farms.In this paper,we have collected data for the sites with the capacity factor(key determinant of value of power plant)of 25%or above for 600 kW wind turbine and applied Multi-Criteria Decision Method to find the most suitable to least suitable site for the installation of wind farm with respect to different factors/criteria.Analytic Hierarchy Process is used to evaluate four potential sites based on the criteria of wind speed(m/s),wind power density(W/m^(2)),distance from grid station(km),capacity factor,transport cost and population density.Results show that the preference of site largely depends on the average annual wind speed and wind power density.Our study is helpful for government as they verify the findings of Pakistan Meteorological Department but with different approach. | Yousaf Ali Masab Butt Muhammad sabir Ubaidullah Mumtaz Aneel Salman | 2018 | Journal of Control and Decision2018，5，2： | 1 |
| 10 | Interleukirr - 6 in the cerebrospinal fluid after perinatal asphyxia is related to early and late neurological manifestations显示文摘 | Martirr Aneel A | 1997 | Pediatrics1997，100，： | 1 |
| 11 | The Association of Active Cancer With Venous Thromboembolism Location: A Population-Based Study显示文摘 | Alfonso J. Tafur Henna Kalsi Waldemar E. Wysokinski Robert D. McBane Aneel A. Ashrani Randolph S. Marks Daniel J. Crusan Tanya M. Petterson Kent R. Bailey John A. Heit | 2011 | Mayo Clinic Proceedings2011，，1： | 1 |
| 12 | Single-incision laparoscopic colectomy: training the next generation显示文摘 | Seth Miller Marlin Wayne Causey Aneel Damle Justin Maykel Scott Steele | 2013 | Surgical Endoscopy2013，，5： | 1 |
| 13 | The case against corporate social responsibility显示文摘 | Aneel Karnani | 2010 | Wall Street Journal2010，17，02： | 1 |
| 14 | Incidence and cost burden of post-thrombotic syndrome显示文摘 | Aneel A. Ashrani John A. Heit | 2009 | Journal of Thrombosis and Thrombolysis2009，，4： | 1 |
| 15 | Epithelial mesenchymal transition in colorectal cancer: Seminal role in promoting disease progression and resistance to neoadjuvant therapy显示文摘 | Aneel Bhangu Gemma Wood Alex Mirnezami Ara Darzi Paris Tekkis Robert Goldin | 2012 | Surgical Oncology2012，，4： | 1 |
| 16 | Incidence and cost burden of post-thrombotic syndrome显示文摘 | Aneel A. Ashrani John A. Heit | 2009 | Journal of Thrombosis and Thrombolysis2009，，： | 1 |
| 17 | White matter damage and intra- ventrieular hemorrhage in very pretenn infants: the EPIPAGE study 显示文摘 | Larroque B Manet S Aneel PY | 2003 | J Pediatr2003，143，4： | 1 |
| 18 | The impact of timing of cholecystectomy following gallstone pancreatitis显示文摘 | Marianne Johnstone Paul Marriott T. James Royle Caroline E. Richardson Andrew Torrance Elizabeth Hepburn Aneel Bhangu Abhilasha Patel David C. Bartlett Thomas D. Pinkney | 2013 | The Surgeon2013，，： | 1 |
| 19 | Therapy‐related acute promyelocytic leukemia: observations relating to APL pathogenesis and therapy*显示文摘 | Michelle A.Elliott LouisLetendre AyalewTefferi William J.Hogan ChristopherHook Scott H.Kaufmann Rajiv K.Pruthi AnimeshPardanani Kebede H.Begna Aneel A.Ashrani Alexandra P.Wolanskyj ArefAl‐Kali Mark R.Litzow | 2012 | European Journal of Haematology2012，，3： | 1 |
| 20 | Crystal Structure of the SF3 Helicase from Adeno-Associated Virus Type 2显示文摘 | J.Anson James Carlos R. Escalante Miran Yoon-Robarts Thomas A. Edwards R.Michael Linden Aneel K. Aggarwal | 2003 | Structure2003，，： | 1 |
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