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| 1 | Colorectal liver metastases: Current management and future perspectives显示文摘The liver is the commonest site of metastatic disease for patients with colorectal cancer,with at least 25%developing colorectal liver metastases(CRLM)during the course of their illness.The management of CRLM has evolved into a complex field requiring input from experienced members of a multi-disciplinary team involving radiology(cross sectional,nuclear medicine and interventional),Oncology,Liver surgery,Colorectal surgery,and Histopathology.Patient management is based on assessment of sophisticated clinical,radiological and biomarker information.Despite incomplete evidence in this very heterogeneous patient group,maximising resection of CRLM using all available techniques remains a key objective and provides the best chance of long-term survival and cure.To this end,liver resection is maximised by the use of downsizing chemotherapy,optimisation of liver remnant by portal vein embolization,associating liver partition and portal vein ligation for staged hepatectomy,and combining resection with ablation,in the context of improvements in the functional assessment of the future remnant liver.Liver resection may safely be carried out laparoscopically or open,and synchronously with,or before,colorectal surgery in selected patients.For unresectable patients,treatment options including systemic chemotherapy,targeted biological agents,intraarterial infusion or bead delivered chemotherapy,tumour ablation,stereotactic radiotherapy,and selective internal radiotherapy contribute to improve survival and may convert initially unresectable patients to operability.Currently evolving areas include biomarker characterisation of tumours,the development of novel systemic agents targeting specific oncogenic pathways,and the potential reemergence of radical surgical options such as liver transplantation. | Jack Martin Angelica Petrillo Elizabeth C Smyth Nadeem Shaida Samir Khwaja HK Cheow Adam Duckworth Paula Heister Raaj Praseedom Asif Jah Anita Balakrishnan Simon Harper Siong Liau Vasilis Kosmoliaptsis Emmanuel Huguet | 2020 | World Journal of Clinical Oncology2020,11,10: | 5 |
| 2 | Lysosome-related organelles显示文摘 | Dell'Angelica EC Mullins C Caplan S | 2000 | FASEB J2000,14,10: | 1 |
| 3 | Lysosome-related organelles显示文摘 | Dell'Angelica EC Mullins C Caplan S | 2000 | FASEB J2000,14,10: | 1 |
| 4 | IQM3 : Information Quality Management Maturity Model 显示文摘 | Caballero I C Angelica C Cord | 2008 | Journal of Universal Computer Science2008,14,22: | 1 |
| 5 | Phase II Trial of Hepatic Artery Infusional and Systemic Chemotherapy for Patients With Unresectable Hepatic Metastases From Colorectal Cancer:Conversion to Resection and Long-term Outcomes显示文摘 | D’angelica MI Correa-Gallego C | 2014 | Ann Surg2014,,: | 1 |
| 6 | Applying a student modeling with non-monotonic diagnosis to Intelligent Virtual Environment for Training/Instruction 显示文摘 | Julia C Jaime R Angelica D A | 2014 | Expert Systems with Applications2014,41,2: | 1 |
| 7 | Operative drainage following pancreatic resection: analysis of 1122 pa- tients resected over 5 years at a single institution 显示文摘 | Correa-Gallego C Brennan M D'angelica M | 2013 | Ann Surg2013,258,6: | 1 |
| 8 | Differential diagnosis of proximal biliary obstruction显示文摘 | Are C Gonen M D'Angelica M | 2006 | Surgery2006,140,5: | 1 |
| 9 | Differential diagnosis of proxinmal biliary obstruction显示文摘 | Are C Gonen M D'Angelica M | | 0,,05: | 1 |
| 10 | Melanosome biogenesis: Shedding light on the origin of an obscure organelle显示文摘 | Dell Angelica E C | 2003 | Trends in Cell Biology2003,13,10: | 1 |
| 11 | Hepatitis B virus e antigen specific epitopes and limitations of commercial anti-HBe immunoassays显示文摘 | Mark AB Angelica MS Doris C | 2000 | J Med Virol2000,60,: | 1 |
| 12 | Differential diagnosis of proximal biliary obstruction显示文摘 | Are C Gonen M D'Angelica M | 2006 | Surgery2006,140,5: | 1 |
| 13 | Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein显示文摘 | Petra N Angelica C Raffaele DF | 1999 | J virol1999,73,12: | 1 |
| 14 | Operativedrainage following pancreatic resection: Analysis of 1122 pa-tients resected over 5 years at a single institution 显示文摘 | Correa-Gallego C Brennan MF D'Angelica M | 2013 | AnnalSurg2013,258,6: | 1 |
| 15 | Current role of therapeutic laparoscopy and thoracoscopy in the management of malignancy:a review of trends from a tertiary care cancer center显示文摘 | Are C Brennan MF D7 Angelica M | 2008 | J Am Coll Surg2008,206,: | 1 |
| 16 | Purification and structural characterization of a fatty acid-binding protein from the liver of the catfish Rhamdia sapo显示文摘 | DI PIETRO S M DELL' ANGELICA E C SCHLEICHER C H | 1996 | Comparative of Biochemistry and Physiology Part B:Biochemistry & Molecular Biology1996,113,3: | 1 |
| 17 | Phase II trial of hepatic artery infusional and systemic chemotherapy for pa- tients with unresectable hepatic metastases from colorectal can- cer:conversion to resection and long-term outcomes 显示文摘 | D'Angelica M Correa-Gallego C Paty P | 2015 | Ann Surg2015,261,2: | 1 |
| 18 | Diferential diagnosis of proximal biliary obst ruction显示文摘 | Are C Gonen MD Angelica M | 2006 | Surgery2006,140,5: | 1 |
| 19 | Operative drainage following pancreatic resection: analysis of 1 122 patients resected over 5 years at a single institution 显示文摘 | Correa-Gallego C Brennan M D'Angelica M | 2013 | Ann Surg2013,258,6: | 1 |
| 20 | Melanosome biogenesis:shedding light on the origin of an obscure organelle显示文摘 | DELL' ANGELICA E C | 2003 | Trends in Cell Biology2003,13,10: | 1 |