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| 1 | Preparation and morphology studies of core-shell type waterborne polyacrylate-polyurethane microspheres显示文摘 | Anjie Dong Yingli An Shiyou Feng | 1999 | Journal of Colloid and Interface Science1999，214，： | 1 |
| 2 | Synthesis and properties of O-carboxymethyl chitosan/poly(ethylene glycol) graft copolymers显示文摘 | Dong Anjie Feng Menghuang Qi Haiying | 2008 | Journal of Materials Science:Materials in Medicine2008，2，19： | 1 |
| 3 | Carbazyl RAFT agents synthesized by an improved aqueous phase method and their applications in RAFT polymerization显示文摘 | Jianhua Zhang Anjie Dong Tongyu Cao Ruiwei Guo | 2008 | European Polymer Journal2008，，： | 1 |
| 4 | Preparation and morphology studies of core-shell type waterborne polyacrylatepolyurethane microspheres显示文摘 | Dong Anjie An Yingli Feng Shiyou | 1999 | Journal of Colloid and Interface Science1999，214，： | 1 |
| 5 | Preparation and morphology studies of core-shell type waterborne polyacrylate-polyurethane micropheres显示文摘 | Dong Anjie An Yingli Feng Shiyou | 1999 | Jounral of Colloid and Interface Science1999，21，4： | 1 |
| 6 | Preparation and morphology studies of core - shell type waterborne polyacyrlate - polyurethane microspheres 显示文摘 | Dong Anjie Feng Shiyou Sun Duoxian | 1999 | Jour- nal of Colloid and Interface Science1999，，214： | 1 |
| 7 | Preparation and morphology studies of core-shell type waterborne polyacrylate-polyurethane microspheres显示文摘 | Dong Anjie An Yingli Feng Shiyou | 1999 | Journal of Colloid and Interface Science1999，214，： | 1 |
| 8 | Preparation and morphology studies of core-shell type waterborne polyacrylate-polyurethane microspheres 显示文摘 | Dong Anjie An Yingli Feng Shiyou | 1999 | Journal of Colloid and Interface Science1999，214，1： | 1 |
| 9 | 显示文摘 | Dong Anjie Feng Menghuang Qi Haiying | 2008 | Journal of Materials Science: Materials in Medicine2008，19，2： | 1 |
| 10 | Preparation and Morphology Studies of Core-Shell Type Waterborne Polyacrylate–Polyurethane Microspheres显示文摘 | Anjie Dong Yingli An Shiyou Feng Duoxian Sun | 1999 | Journal of Colloid And Interface Science1999，，1： | 1 |
| 11 | Methoxy poly(ethylene glycol)-b-poly(ethyl cyanoacrylate) copolymer nanoparticles as delivery vehicles for dexamethasone显示文摘Methoxy poly(ethylene oxide)-b-poly(ethyl cyanoacrylate) (mPEG-b-PECA), amphiphilic block copolymer, was synthesized via oxyanion-initiated polymerization with a sodium alcoholate-terminated monomethoxy poly(ethylene glycol) as the macroinitiator. mPEG-b-PECA was characterized by GPC, 1H-NMR and FTIR. The results indicate that the structure of mPEG-b-PECA is well controlled with narrow molecular weight distribution. The dexamethasone (DXM)-loaded mPEG-b-PECA nanoparticles (NPs) were prepared by the nanoprecipitation technique and characterized by LPSA, 1H-NMR and TEM. The DXM-loaded mPEG-b-PECA NPs are of spherical shape with the size of less than 100 nm. The drug-loaded amount (DL) and encapsulation efficiency (EE) of DXM-loaded NPs were investigated by HPLC. The results show that DXM can be effectively incorporated into mPEG-b-PECA NPs, which provides a potential delivery system for DXM and other hydrophobic drugs. | ZHAI YingLei DENG LianDong LIN XiaoNa XIAO Li JIN FengMin DONG AnJie | 2009 | Chinese Science Bulletin2009，54，17： | 1 |
| 12 | The microgravity enhanced polymer-mediated siRNA gene silence by improving cellular uptake显示文摘Microgravity(MG)effect is a weightlessness phenomenon caused by the distance from the ground or low gravity of other planets outside the earth's atmosphere.The various effects of MG have been corroborated in human and animal studies and modeled in cell-based analogs.However,the impact of MG on siRNA performance remains to be elucidated,which is crucial for aerospace medicine.In this study,we prepared nucleic acid nanomicelles(EAASc/siRNA)by using tri-block copolymer of PEG45-PAMA40-P(C7A36-DBA37)(EAASc)and siRNA and explored its working mechanism under simulated microgravity(SMG)condition generated by a random positioning machine(RPM).The binding ability of EAASc to siRNA and silence activity were firstly confirmed in normal gravity(NG)environment.Evaluation of PLK1 mRNA expression revealed that gene inhibition efficiencies were increased by 28.7%(HepG2)and 28.9%(A549)under SMG condition,compared with those under NG condition.In addition,mechanism exploration indicated that morphology and migration capability of cancer cells were significantly changed,the internalization of EAASc/siRNA by cells was magnified when the cells were incubated with RPM.No significant difference was observed regarding the expression profiles of genes involved in RNA interference(RNAi)pathway,including Ago2,Dicer,TRBP,and so on.Taken together,siRNA activity was elevated under SMG condition owning to increased cellular internalization.This study,for the first time to our knowledge,provides valuable theory for development and application of siRNA therapeutic in space in the future. | Tongren Yang Chanchan Yu Changrong Wang Chunhui Li Mengjie Zhang Xiaofan Luo Yuhua Weng Anjie Dong Xiaoqiong Li Yulin Deng Yuanyu Huang | 2020 | Biophysics Reports2020，6，6： | 1 |
| 13 | Titanium alloy composited with dual-cytokine releasing polysaccharide hydrogel to enhance osseointegration via osteogenic and macrophage polarization signaling pathways显示文摘Titanium alloy has been widely used in orthopedic surgeries as bone defect filling.However,the regeneration of high-quality new bones is limited due to the pro-inflammatory microenvironment around implants,resulting in a high occurrence rate of implant loosening or failure in osteological therapy.In this study,extracellular matrix-mimetic polysaccharide hydrogel co-delivering BMP-2 and interleukin(IL)-4 was composited with 3D printed titanium alloy to promote the osseointegration and regulate macrophage response to create a pro-healing microenvironment in bone defect.Notably,it is discovered from the bioinformatics data that IL-4 and BMP-2 could affect each other through multiple signal pathways to achieve a synergistic effect toward osteogenesis.The composite scaffold significantly promoted the osteoblast differentiation and proliferation of human bone marrow mesenchyme stem cells(hBMSCs).The repair of large-scale femur defect in rat indicated that the dual-cytokinedelivered composite scaffold could manipulate a lower inflammatory level in situ by polarizing macrophages to M2 phenotype,resulting in superior efficacy of mature new bone regeneration over the treatment of native titanium alloy or that with an individual cytokine.Collectively,this work highlights the importance of M2-type macrophages-enriched immune-environment in bone healing.The biomimetic hydrogel–metal implant composite is a versatile and advanced scaffold for accelerating in vivo bone regeneration,holding great promise in treating orthopedic diseases. | Yaping Wang Zujian Feng Xiang Liu Chunfang Yang Rui Gao Wenshuai Liu Wenbin Ou-Yang Anjie Dong Chuangnian Zhang Pingsheng Huang Weiwei Wang | 2022 | Regenerative Biomaterials2022，9，1： | 0 |
| 14 | THE STUDIES ON DEGRADATIVE KINETIC OF MEDICAL CHITOSAN显示文摘THESTUDIESONDEGRADATIVEKINETICOFMEDICALCHITOSANTHESTUDIESONDEGRADATIVEKINETICOFMEDICALCHITOSANSunDuoxian;DongAnjie(Department... | Sun Duoxian Dong Anjie(Department of Applied ChemistryTianjin University, Tianjin, 300072,China) | 1994 | Chinese Journal of Biomedical Engineering(English Edition)1994，3，3： | 0 |
| 15 | Visualization of Boiling Heat Transfer on Copper Surface with Different Wettability显示文摘In this work, a pool boiling visualization experiment platform was built to study the influence of wettability on the nucleate boiling heat transfer. The copper surface was prepared by chemical etching method, and three types of copper surfaces(hydrophilic, hydrophobic, and smooth) were obtained. The boiling heat transfer characteristics of these three surfaces were discussed based on the obtained heat transfer curves and the heat transfer coefficient(HTC) curves. It was found that the HTC still increases when the boiling heat transfer closes the critical heat flux(CHF). To better evaluate the boiling heat transfer efficiency, the concept of heat flux growth rate per unit superheat is introduced. The dynamic behaviors of single and multiple bubbles were also recorded to study the mechanism of the boiling heat transfer. The bubble behavior characteristics show good consistent with the proposed heat flux growth rate. By comparing the heat transfer curves and the bubble dynamic behavior, the following characters of boiling heat exchange can be found: At low heat flux, the heat exchange is dominated by the bubble coverage on the surface, and the hydrophobic surface has better boiling heat transfer efficiency than the hydrophilic surface. As the heat flux increases, the vapor channel connecting a big bubble and the wall surface plays an important role in enhancing the heat transfer. The polymerization of bubbles on the hydrophobic surface forms bubble films and breaks the vapor channel, leading to a significantly smaller HTC and a lower CHF than that of the hydrophilic surface. The HTC of hydrophilic surface in this work can reach up to 54.85 kW/(m^(2)·K), which is 2.3 times the hydrophobic surface. | LIU Dong LI Yunheng HU Anjie | 2022 | Journal of Thermal Science2022，31，6： | 0 |
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