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| 1 | Endoscopic hemostasis techniques for upper gastrointestinal hemorrhage: A review显示文摘Upper gastrointestinal hemorrhage (UGIH) is an urgent disease that is often encountered in daily medical practice. Endoscopic hemostasis is currently indispensable for the treatment of UGIH. Initially, when UGIH is suspected, a cause of UGIH is presumed from the medical interview and physical findings. After ample primary treatment, urgent endoscopy is performed. Many methods of endoscopic hemostasis are in wide use, including hemoclip, injection and thermo-coagulation methods. Although UGIH develops from a wide variety of diseases, such as esophageal varices and gastric and duodenal ulcer, hemostasis is almost always possible. Identification of the causative diseases, primary treatment and characteristic features of endoscopic hemostasis are needed to allow appropriate treatment. | Hajime Anjiki Terumi Kamisawa Masaki Sanaka Taro Ishii Yasushi Kuyama | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，2： | 13 |
| 2 | Diagnosis and clinical implications of pancreatobiliary reflux显示文摘Oddi 的括约肌在远侧的结束被定位胰腺并且胆汁管并且调整胆汁和胰液的流出。一条普通隧道能那么长连接胰腺并且胆汁管在十二指肠的墙外面被定位,,发生在 pancreaticobiliary maljunction (PBM ) ;在如此的情况中,括约肌行动机能上地不影响连接。因为在胰腺的管以内的水疗院压力通常比在胆汁管大,胰液经常倒流进在 PBM 的胆汁的管(pancreatobiliary 倒流) ,导致致癌物在胆道的非位的条件。Pancreatobiliary 倒流能经由次要的十二指肠的乳头状的小突起在胆汁,刺激分泌素的动态磁性的回声 cholangiopancreatography,和 pancreatography 从提高的淀粉酶水平被诊断。最近,没有 PBM, pancreatobiliary 倒流能发生在个人,变得明显。没有 PBM, Pancreatobiliary 倒流可能甚至在一些个人与胆汁的致癌作用有关。因为很少全身的研究与正常 pancreaticobiliary 连接在个人关于 pancreatobiliary 倒流的临床的关联和含意存在,包括适当管理的进一步未来的临床的研究应该被执行。 | Terumi Kamisawa Hajime Anjiki Naoto Egawa Masanao Kurata Goro Honda Kouji Tsuruta | 2008 | World Journal of Gastroenterology2008，14，43： | 12 |
| 3 | Sclerosing cholangitis associated with autoimmune pancreatitis differs from primary sclerosing cholangitis显示文摘AIM:To clarify the characteristic features of biliary le-sions in patients with autoimmune pancreatitis(AIP) and compare them with those of primary sclerosing cholangitis(PSC) .METHODS:The clinicopathological characteristics of 34 patients with sclerosing cholangitis(SC) associated with AIP were compared with those of 4 patients with PSC.RESULTS:SC with AIP occurred predominantly in el-derly men.Obstructive jaundice was the most frequent initial symptom in SC with AIP.Only SC patients with AIP had elevated serum IgG4 levels,and sclerosing diseases were more frequent in these patients.SC pa-tients with AIP responded well to steroid therapy.Seg-mental stenosis of the lower bile duct was observed only in SC patients with AIP,but a beaded and pruned-tree appearance was detected only in PSC patients.Dense infi ltration of IgG4-positive plasma cells was de-tected in the bile duct wall and the periportal area,as well as in the pancreas,of SC patients with AIP.CONCLUSION:SC with AIP is distinctly different from PSC.The two diseases can be discriminated based on cholangiopancreatographic findings and serum IgG4 levels. | Terumi Kamisawa Kensuke Takuma Hajime Anjiki Naoto Egawa Masanao Kurata Goro Honda Kouji Tsuruta | 2009 | World Journal of Gastroenterology2009，15，19： | 9 |
| 4 | Endoscopic approach for diagnosing autoimmune pancreatitis显示文摘It is of utmost importance to differentiate autoimmune pancreatitis(AIP) from pancreatic cancer(PC).Segmental AIP cases are sometimes difficult to differentiate from PC.On endoscopic retrograde cholangio pancreatography,long or skipped irregular narrowing of the main pancreatic duct(MPD),less upstream dilatation of the distal MPD,side branches derived from the narrowed portion of the MPD,absence of obstruction of the MPD,and stenosis of the intrahepatic bile duct suggest AIP rather than PC.Abundant infiltration of IgG4-positive plasma cells is frequently and rather specifically detected in the major duodenal papilla of AIP patients.IgG4-immunostaining of biopsy specimens obtained from the major duodenal papilla is useful for supporting a diagnosis of AIP with pancreatic head involvement.On endoscopic ultrasonography(EUS),hyperechoic spots in the hypoechoic mass and the duct-penetrating sign suggest AIP rather than PC.EUS and intraductal ultrasonography sometimes show wall thickening of the common bile duct even in the segment in which abnormalities are not clearly observed with cholangiography in AIP patients.EUS-guided fine needle aspiration,especially EUS-guided Tru-Cut biopsy,is useful to diagnose AIP,as well as to exclude PC. | Terumi Kamisawa Hajime Anjiki Kensuku Takuma Naoto Egawa Takao Itoi Fumihide Itokawa | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，1： | 6 |
| 5 | Effect of herbal medicine Juzentaihoto on hepatic and intestinal heat shock gene expression requires intestinal microflora in mouse显示文摘AIM: To evaluate the role of intestinal microflora in the effects of multi-herbal medicine on gene expression in the gut and liver. METHODS: The multi-herbal medicine Juzentaihoto (JTX) was administered to five germ-free mice and regular mice for 2 wk. Among the results of the comprehensive gene chip analysis of the intestine and liver, we featured heat shock proteins (HSPs) 70 and 105 because their gene expression changed only in the presence of microflora. Real-time RT-PCR was performed to confirm the expression levels of these HSP genes. To determine whether JTX acts directly on the HSP genes, sodium arsenite (SA) was used to induce the heat shock proteins directly. To examine the change of the intestinal microflora with administration of JTX, the terminal restriction fragment polymorphism (T-RFLP) method was used. To identify the changed bacteria, DNA sequencing was performed. RESULTS: Heat shock protein gene expression,documented by gene chip and real-time RT-PCR, changed with the administration of JTX in the regular mice but not in the germ-free mice. JTX did not suppress the direct induction of the HSPs by SA. T-RFLP suggested that JTX decreased unculturable bacteria and increased Lactobacillus johnsoni. These data suggested that JTX changed the intestinal microflora which, in turn, changed HSP gene expression. CONCLUSION: Intestinal microflora affects multi-herbal product JTX on the gene expression in the gut and liver. | Miho Kato Atsushi Ishige Naoko Anjiki Masahiro Yamamoto Yoshifumi Irie Mitsue Taniyama Ryoko Kibe Junichiro Oka Yoshimi Benno Kenji Watanabe | 2007 | World Journal of Gastroenterology2007，13，16： | 5 |
| 6 | Differentiation of autoim- mune pancreatitis from pancreatic cancer by diffusionweighted MRI 显示文摘 | Kamisawa T Takuma K Anjiki H | 2010 | Am J Gastroenterol2010，105，8： | 1 |
| 7 | Incidence of and risk factors for developing pancreatic cancer in patients with chronic pancreatitis显示文摘 | Kudo Y Kamisawa T Anjiki H | 2011 | Hepatogastroenterology2011，58，106： | 1 |
| 8 | Metachronousextrapancreatic lesions in autoimmune pancreatitis显示文摘 | Takuma K Kamisawa T Anjiki H | 2010 | InternMed2010，49，6： | 1 |
| 9 | Juxtapapillary duodenal diverticula and pancreatobiliary disease显示文摘 | Egawa N Anjiki H Takuma K | | 0，，2： | 1 |
| 10 | Dual effects of rebeprazole on solid - phase gastric emptying assessed by the 13 C - octan - oate breath tes显示文摘 | Anjiki H Sanaka M Kuyama Y | 2005 | Digestion2005，72，23： | 1 |
| 11 | Differentiation of autoimmune pancreatitis from pancreatic cancer by diffusion- weightedMR显示文摘 | Kamisawa T Takuma K Anjiki H | 2010 | Am J Gastroenterol2010，105，： | 1 |
| 12 | Pancreaticobiliary maliunction显示文摘 | Kamisawa T Takuma K Anjiki H | 2009 | Clin Gastroenterol Hepatol2009，7，11： | 1 |
| 13 | FDG-PET/CT findings of autoimmune pancreatitis 显示文摘 | Kamisawa T Takum K Anjiki H | 2010 | Hepatogastroenterology2010，57，99： | 1 |
| 14 | Effects of agar and pectin on gastric emptying and post-prandial glycaemic profiles in healthy human volunteers 显示文摘 | Sanaka M Yamamoto T Anjiki H | 2007 | Clinical and Experimental Pharmacology and Physiology2007，34，11： | 1 |
| 15 | Allergic manifesta- tions in autoimmune pancreatitis 显示文摘 | Kamisawa T Anjiki H Egawa N | 2009 | Eur J Gastroenterol Hepatol2009，21，10： | 1 |
| 16 | Differentiation of autoimmune pancreatitis from pancreatic cancer by diffusion- weighted MRI显示文摘 | Kamisawa T Takuma K Anjiki H | 2010 | Am J Gastroenterol2010，105，8： | 1 |
| 17 | Juxtapapillary duodenal diverticula and pancreatobiliary disease 显示文摘 | Egawa N Anjiki H Takuma K | 2010 | Dig Surg2010，27，2： | 1 |
| 18 | Differentiation of autoimmune pancreatitis from pancreatic cancer by dif- fusion-weighted MRI显示文摘 | Kamisawa T Takuma K Anjiki H | 2010 | Am J Gastroenterol2010，105，8： | 1 |
| 19 | Incidence of and risk factors for developing pancreatic cancer in patients with chronic pancreatitis 显示文摘 | Kudo Y Kamisawa T Anjiki H | 2011 | Hepato-gastroenterology2011，58，106： | 1 |
| 20 | Differentiafion of autoimmune pancreatitis from pancreatic cancer by diffusion -weighted MRI显示文摘 | Kamisawa T TakuIna K Anjiki H | 2010 | Am J Gastroenterol2010，105，： | 1 |
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