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| 1 | A new prognostic histopathologic classification of nasopharyngeal carcinoma显示文摘Background:The current World Health Organization(WHO) classification of nasopharyngeal carcinoma(NPC) con?veys little prognostic information.This study aimed to propose an NPC histopathologic classification that can poten?tially be used to predict prognosis and treatment response.Methods:We initially developed a histopathologic classification based on the morphologic traits and cell differentia?tion of tumors of 2716 NPC patients who were identified at Sun Yat?sen University Cancer Center(SYSUCC)(training cohort).Then,the proposed classification was applied to 1702 patients(retrospective validation cohort) from hospitals outside SYSUCC and 1613 patients(prospective validation cohort) from SYSUCC.The efficacy of radiochemotherapy and radiotherapy modalities was compared between the proposed subtypes.We used Cox proportional hazards models to estimate hazard ratios(HRs) with 95% confidence intervals(CI) for overall survival(OS).Results:The 5?year OS rates for all NPC patients who were diagnosed with epithelial carcinoma(EC;3708 patients),mixed sarcomatoid?epithelial carcinoma(MSEC;1247 patients),sarcomatoid carcinoma(SC;823 patients),and squamous cell carcinoma(SCC;253 patients) were 79.4%,70.5%,59.6%,and 42.6%,respectively(P < 0.001).In mul?tivariate models,patients with MSEC had a shorter OS than patients with EC(HR = 1.44,95% CI = 1.27–1.62),SC(HR = 2.00,95% CI = 1.76–2.28),or SCC(HR = 4.23,95% CI = 3.34–5.38).Radiochemotherapy significantly improved survival compared with radiotherapy alone for patients with EC(HR 49–0.75),and possibly for those with SCC(HR = 0.67,95% CI = 0.56–0.80),MSEC(HR = 0.58,95% CI = 0..74–1.28).= 0.63;95% CI = 0.40–0.98),but not for patients with SC(HR = 0.97,95% CI = 0Conclusions:The proposed classification offers more information for the prediction of NPC prognosis compared with the WHO classification and might be a valuable tool to guide treatment decisions for subtypes that are associ?ated with a poor prognosis. | Hai-Yun Wang Yih-Leong Chang Ka-Fai To Jacqueline S.G.Hwang Hai-Qiang Mai Yan-Fen Feng Ellen T.Chang Chen-Ping Wang Michael Koon Ming Kam Shie-Lee Cheah Ming Lee Li Gao Hui-Zhong Zhang Jie-Hua He Hao Jiang Pei-Qing Ma Xiao-Dong Zhu Liang Zeng Chun-Yan Chen Gang Chen Ma-Yan Huang Sha Fu Qiong Shao An-Jia Han Hai-Gang Li Chun-Kui Shao Pei-Yu Huang Chao-Nan Qian Tai-Xiang Lu Jin-Tian Li Weimin Ye Ingemar Ernberg Ho Keung Ng Joseph T.S.Wee Yi-Xin Zeng Hans-Olov Adami Anthony T.C.Chan Jian-Yong Shao | 2016 | Chinese Journal of Cancer2016，35，6： | 10 |
| 2 | Current developments in natural orifices transluminal endoscopic surgery:An evidence-based review显示文摘Tremendous advances have been made in recent years addressing the key obstacles to safe performance and introduction of human natural orifice transluminal endoscopic surgery (NOTES). Animal studies have focused on identifying optimal solutions to these obstacles, in particular methods of creating transluminal access,safe closure of the point of access, and development of a multitasking platform with dedicated instruments. Whether the performance data generated from these animal studies can be reproduced in humans has yet to be determined. Reports of human NOTES procedures are emerging, and the possibility of accomplishing human NOTES based on existing technology has been demonstrated. However, dedicated platforms and devices are still lacking to allow for pure NOTES procedures, and whether NOTES can deliver the postulated benef its of earlier recovery and improved cosmesis remains uncertain. | Anthony Yuen Bun Teoh Philip Wai Yan Chiu Enders Kwok Wai Ng | 2010 | World Journal of Gastroenterology2010，16，38： | 7 |
| 3 | Difficulties and outcomes in starting endoscopic submucosal dissection显示文摘 | Anthony Yuen Bun Teoh Philip Wai Yan Chiu Simon Kin Hung Wong Joseph Jao Yiu Sung James Yun Wong Lau Enders Kwok Wai Ng | 2010 | Surgical Endoscopy2010，，5： | 3 |
| 4 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 2 |
| 5 | Does board gender diversity improve the informativeness of stock prices?显示文摘 | Ferdinand A. Gul Bin Srinidhi Anthony C. Ng | 2011 | Journal of Accounting and Economics2011，，3： | 2 |
| 6 | A modified analytical solution of soil stress distribution for XCC pile foundations显示文摘 | Yaru Lv Hanlong Liu Charles W. W. Ng Anthony Gunawan Xuanming Ding | 2014 | Acta Geotechnica2014，，3： | 1 |
| 7 | Business Sustain- ability Performance and Cost of Equity Capital 显示文摘 | Anthony C Ng Zabihollah Rezaee | 2015 | Jour- nal of Corporate Finanee2015，34，： | 1 |
| 8 | Biliary Cystadenoma and Other Complicated Cystic Lesions of The Liver: Diagnostic and Therapeutic Challenges显示文摘 | Anthony Y.B. Teoh MBChB Simon S.M. Ng MBChB K.F. Lee MBBS Paul B.S. Lai MBChB MD | 2006 | World Journal of Surgery2006，，8： | 1 |
| 9 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 10 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng Ka Lau Leung Janet F. Y. Lee Raymond Y. C. Yiu Jimmy C. M. Li Anthony Y. B. Teoh Wing Wa Leung | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 11 | Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis显示文摘 | Pierre Blanchard Anne Lee Sophie Marguet Julie Leclercq Wai Tong Ng Jun Ma Anthony T C Chan Pei-Yu Huang Ellen Benhamou Guopei Zhu Daniel T T Chua Yong Chen Hai-Qiang Mai Dora L W Kwong Shie Lee Cheah James Moon Yuk Tung Kwan-Hwa Chi George Fountzilas Li | 2015 | The Lancet Oncology2015，，： | 1 |
| 12 | Endoscopic suturing is superior to endoclips for closure of gastrotomy after natural orifices translumenal endoscopic surgery (NOTES): an ex vivo study显示文摘 | Liu Liu Philip Wai Yan Chiu Anthony Yuen Bun Teoh Candice Chuen Hing Lam Enders Kwok Wai Ng James Yun Wong Lau | 2014 | Surgical Endoscopy2014，，4： | 1 |
| 13 | Laparoscopic Management of 4 Cases of Recurrent Cornual Ectopic Pregnancy and Review of Literature显示文摘 | Anthony Siow Selma Ng | 2011 | The Journal of Minimally Invasive Gynecology2011，，3： | 1 |
| 14 | Ex vivo comparative study using the Endolifter ? as a traction device for enhancing submucosal visualization during endoscopic submucosal dissection显示文摘 | Anthony Yuen Bun Teoh Philip Wai Yan Chiu So Fei Hon Tony Wing Chung Mak Enders Kwok Wai Ng James Yun Wong Lau | 2013 | Surgical Endoscopy2013，，4： | 1 |
| 15 | SJWD14072900000111显示文摘 | Jin Yao Teo Brian Kim Poh Goh Foong Koon Cheah John Carson Allen Richard Hoau Gong Lo David Chee Eng Ng Anthony Soon Whatt Goh Andrew Yu Keat Khor Hui Shan Sim Jia Jun Ng Pierce Kah‐Hoe Chow | 2014 | Journal of Digestive Diseases2014，，8： | 1 |
| 16 | Laparoscopic management of 53 cases of cornual ectopic pregnancy显示文摘 | Selma Ng Suttha Hamontri Irene Chua Bernard Chern Anthony Siow | 2009 | Fertility and Sterility2009，，2： | 1 |
| 17 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 18 | Difficulties and outcomes in starting endoscopic submucosal dissection显示文摘 | Anthony Yuen Bun Teoh Philip Wai Yan Chiu Simon Kin Hung Wong Joseph Jao Yiu Sung James Yun Wong Lau Enders Kwok Wai Ng | 2010 | Surgical Endoscopy2010，，5： | 1 |
| 19 | In-House Networks Using Multimode Polymer Optical Fiber for Broadband Wireless Services显示文摘 | Ton Koonen Anthony Ng’oma Peter Smulders Henrie van den Boom Idelfonso Tafur Monroy Giok-Djan Khoe | 2003 | Photonic Network Communications2003，，2： | 1 |
| 20 | A sian‐ C hinese patient perceptions of natural orifice transluminal endoscopic surgery cholecystectomy显示文摘 | Anthony Yuen Bun Teoh Enders Kwok Wai Ng Alana Chock Lee Swanstrom Shyam Varadarajulu Philip Wai Yan Chiu | 2014 | Digestive Endoscopy2014，，3： | 1 |
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