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| 1 | 拉米夫定/干扰素-α联合治疗围生期感染乙肝的免疫耐受患儿:一项初步研究显示文摘Objective:To investigate whether combining the antiviral effect of lamivudine with the immune-boosting action of interferon-alpha(IFN-α)is effective in treating hepatitis B virus(HBV)“immunotolerant”children.Study design:Twen tythree children(8 boys;mean age,10 years)infected during the first year of life(17 Asian,21 with normal aminotransferase levels,15 with HBV-DNA > 1000 pg/mL by hybridization and all with mild histologic changes)were treated with l amivudine(3 mg/kg)for 8 weeks alone and then lamivudine(3 mg/kg)-and IFN-α(5 MU/m2,3 times weekly)in combination for 10 months.Results:Seventy-eight percent became HBV-DNA negative at the end of treatment,5(22%)seroconverted to anti-HBe,4(17%)of whom achieved complete viral control,becoming persis tently HBsAg negative and anti-HBs positive.None had YMDD mutations.The viral status of the patients has not changed after a median follow-up of 40 months(range,36 to 48).Conclusions:This pilot study suggests that lamivudine pretrea tment followed by a combination of lamivudine and IFN-αcan induce complete vir al control in HBV immunotolerant children,hitherto considered poor responders. | D'Antiga L. Aw M. Atkins M. G.Mieli-Vergani 王一飞 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，2，8： | 4 |
| 2 | Immune and viral profile from tolerance to hepatitis B surface antigen clearance: a longitudinal study of vertically hepatitis B virus-infected children on combined therapy显示文摘 | Carey I D'Antiga L Bansal S | 2011 | J Virol2011，85，5： | 1 |
| 3 | Automatic generation of glomerular capillary topological organization 显示文摘 | Antiga L Ene-Lordache B Remuzzi G | 2001 | Microvasc Res2001，62，3： | 1 |
| 4 | Simultaneous HPLC determination with light-scattering detection of lactulose and mannitol in studies of intestinal permeability in pediatrics显示文摘 | Marsilio R D'Antiga L Zancan L | 1998 | Clin Chem1998，44，8： | 1 |
| 5 | Combined lamivudine/in- terferon-alpha treatment in 'immunotolerant' children perina- tally infected with hepatitis B: a pilot study 显示文摘 | D' Antiga L Aw M Atkins M | 2006 | J Pediatr2006，148，： | 1 |
| 6 | Intracranial aneurysm neck size overestimation with 3D rotational angiography: the impact on intra- aneurysmal hemodynamics simulated with computational fluid dynamics 显示文摘 | SCHNEIDERS JJ MARQUERING HA ANTIGA L | 2013 | AJNR Am J Neuroradiol2013，34，1： | 1 |
| 7 | Serum Levels of IL-17 and IL-22 Are Reduced by Etanercept, but not by Acitretin, in Patients with Psoriasis: a Randomized-Controlled Trial显示文摘 | M. Caproni E. Antiga L. Melani W. Volpi E. Del Bianco P. Fabbri | 2009 | Journal of Clinical Immunology2009，，2： | 1 |
| 8 | Serum levels of IL-17 and IL-22 are reduced by etanercept, but not by acitretin, in patients with psoriasis : a randomized-controlled trial 显示文摘 | Caproni M Antiga E Mclani L | 2009 | J Clin Immunol2009，29，2： | 1 |
| 9 | Variation in the carotid bi furcation geometry of young versus older adults: Implications for geometric risk of at heroselerosis 显示文摘 | Thomas JB Antiga L Che SL | 2005 | Stroke2005，36，： | 1 |
| 10 | The comparative effects of tacrolimus and hydrocortisone in adult atopie dermatitis:an im- munohistochemical study 显示文摘 | Caproni M Torchia D Antiga E | 2007 | Br J Dermatol2007，156，2： | 1 |
| 11 | Regulatory T cells in the skin lesions and blood of patients with systemic sclerosis and mor- phoea显示文摘 | Antiga E Quaglino P Bellandi S | 2010 | BrJDermatol2010，162，5： | 1 |
| 12 | Oral curcumin ( Me- riva) is effective as an adjuvant treatment and is able to re- duce IL-22 serum levels in patients with psoriasis vulgaris 显示文摘 | Antiga E Bonciolini V Volpi W | 2015 | Biomed Res Int2015，2015，28： | 1 |
| 13 | Factors affecting formation and rupture of intracranial saccular aneurysms 显示文摘 | Bacigaluppi S Piccinelli M Antiga L | 2014 | Neurosurg Rev2014，37，1： | 1 |
| 14 | The comparative effects of tacrolimus and hydrocortisone in adult atopic dermatitis:an immunohistochemical study显示文摘 | Caproni M Torchia D Antiga E | 2007 | Br J Dermatol2007，156，2： | 1 |
| 15 | Bayes pulmonary embolism assisted diagnosis:a new expert system for clinical use显示文摘 | Cavuto S Antiga L | 2007 | Emerg Med J2007，24，3： | 1 |
| 16 | Immune and viralprofile from tolerance to hepatitis B surface antigen clear-ance: a longitudinal study of vertically hepatitis B virus - in-fected children on combined therapy显示文摘 | CAREY I D'ANTIGA L BANSAL S | 2011 | J Virol2011，85，5： | 1 |
| 17 | Features predicting unresectability in hepatoblastoma 显示文摘 | D'Antiga L Vallortigara F Cillo U Talenti E Rugge M Zanean L | 2007 | Cancer2007，110，5： | 1 |
| 18 | FoxP3-expre-ssing T regulatory cells in atopic dermatitis lesions显示文摘 | Caproni M Antiga E Torchia D | 2007 | Allergy Asthma Proc2007，28，5： | 1 |
| 19 | The spectrum of surgical jaundice in infancy显示文摘 | Davenport M Betalli P D’Antiga L et a1 | 2003 | J Pediatr Surg2003，38，10： | 1 |
| 20 | Serum levels of the regulatory cytokines transforming growth factor-b and interleukin-10 are reduced in patients with discoid lupus erythematosus显示文摘 | E Antiga E Del Bianco EM Difonzo | 2011 | Lupus2011，20，6： | 1 |
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