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| 1 | Optimum chemotherapy in the management of metastatic pancreatic cancer显示文摘Pancreatic cancer is one of the most devastating solid tumors,and it remains one of the most difficult to treat.The treatment of metastatic pancreatic cancer(MPC)is systemic,based on chemotherapy or best supportive care,depending on the performance status of the patient.Two chemotherapeutical regimens have produced substantial benefits in the treatment of MPC:gemcitabine in 1997;and FOLFIRIONOX in 2011.FOLFIRINOX improved the natural history of MPC,with overall survival(OS)of 11.1 mo.Nab-paclitaxel associated with gemcitabine is a newly approved regimen for MPC,with a median OS of 8.6 mo.Despite multiple trials,this targeted therapy was not efficient in the treatment of MPC.Many new molecules targeting the proliferation and survival pathways,immune response,oncofetal signaling and the epigenetic changes are currently undergoing phaseⅠandⅡtrials for the treatment of MPC,with many promising results. | Marwan Ghosn Hampig Raphael Kourie Fadi El Karak Colette Hanna Joelle Antoun Dolly Nasr | 2014 | World Journal of Gastroenterology2014，20，9： | 7 |
| 2 | Anal cancer treatment:Current status and future perspectives显示文摘Anal cancers(AC)are relatively rare tumors.Their incidence is increasing,particularly among men who have sex with other men due to widespread infection by human papilloma virus.The majority of anal cancers are squamous cell carcinomas,and they are treated according to stage.In local and locally advanced AC,concomitant chemoradiation therapy based on mitomycin C and 5-Fluorouracil(5-FU)is the current best treatment,while metastatic AC,chemotherapy with 5-FU and cisplatin remains the gold standard.There are no indications for induction or maintenance therapies in locally advanced tumors.Many novel strategies,such as targeted therapies,vaccination,immunotherapy and photodynamic therapy are in clinical trials for the treatment of AC,with promising results in some indications. | Marwan Ghosn Hampig Raphael Kourie Pamela Abdayem Joelle Antoun Dolly Nasr | 2015 | World Journal of Gastroenterology2015，21，8： | 4 |
| 3 | The contributions of lesion laterality and lesion volume to decision-making impairment follwing frontal lobe damage显示文摘 | Clark L Manes F Antoun N | 2003 | Neuropsychologia2003，41，11： | 1 |
| 4 | Growth promotion of maize and lettuce by phosphate-solubilizing Rhizobium leguminosarum biovar. phaseoli显示文摘 | Rock Chabot Hani Antoun Michel P. Cescas | 1996 | Plant and Soil1996，，2： | 1 |
| 5 | Pulmonary Complications After Elective Liver Transplantation—Incidence, Risk Factors, and Outcome显示文摘 | Eric Levesque Emir Hoti Daniel Azoulay Isabelle Honore Bruno Guignard Eric Vibert Philippe Ichai Fadi Antoun Faouzi Saliba Didier Samuel | 2012 | Transplantation Journal2012，，5： | 1 |
| 6 | Improved adhesion between nickel–titanium shape memory alloy and a polymer matrix via silane coupling agents显示文摘 | N.A. Smith G.G. Antoun A.B. Ellis W.C. Crone | 2004 | Composites Part A2004，，11： | 1 |
| 7 | Growth promo- tion of maize and lettuce by phosphate solubilizing rhizobium legume inorsarum biovar phaseoli 显示文摘 | Chabot R Antoun H Cescas M P | 1996 | Plant Soil1996，184，： | 1 |
| 8 | Letrozole efficacy in the treatment of ganulosa cell tumor of the ovary : A case report 显示文摘 | Kourie HR Kattan J Antoun J | 2013 | Onkologie2013，36，9： | 1 |
| 9 | Pilot study of mutant ras peptide-based vaccine as an adjuvant treatment in pancreatic and colorectal cancers显示文摘 | Antoun Toubaji Moujahed Achtar Maurizio Provenzano Vincent E. Herrin Robert Behrens Michael Hamilton Sarah Bernstein David Venzon Barry Gause Francesco Marincola Samir N. Khleif | 2008 | Cancer Immunology Immunotherapy2008，，9： | 1 |
| 10 | Stimulation de la croissance du maise et de la laitue romaine par desmicroorganismes dissolvant le phosphore inorganique显示文摘 | Chabot R Antoun H Cescas MP | 1993 | Can J Microbiol1993，39，： | 1 |
| 11 | The humanglutathione S- transferase P1 protein is phosphorylated and its metabolic function enhanced by the Ser/Thr protein kinases, cAMP-dependent protein kinase and protein kinase C, in glioblastoma cells 显示文摘 | Lo H W Antoun G R Ali-Osman F | 2004 | Cancer Res2004，64，24： | 1 |
| 12 | Impaired recognition and experience of disgust following brain injury显示文摘 | Calder A.J Keane J Manes F Antoun N & Young A.W | | 0，，： | 1 |
| 13 | Selection of modality of renal replacement therapy显示文摘 | ABI ANTOUN T PALEVSKY P M | 2009 | Semin Dial2009，22，2： | 1 |
| 14 | Extracellular Matrix Associated Protein CYR61 is Linked to Prostate Cancer Development显示文摘 | Katherine B. D’Antonio Antoun Toubaji Roula Albadine Alison M. Mondul Elizabeth A. Platz George J. Netto Robert H. Getzenberg | 2010 | The Journal of Urology2010，，4： | 1 |
| 15 | Hepatic TLR4signaling in obese NAFLD显示文摘 | Sharifnia T Antoun J Verriere TG | 2015 | Am J Physiol Gastrointest Liver Physiol2015，309，4： | 1 |
| 16 | Lithium diisopropylamide as initiator for the anionic polymerization of methacrylates 显示文摘 | Antoun S Teyssie P Jerome R | 1997 | Macromolecules1997，30，： | 1 |
| 17 | Unidirectional flushing : a powerful tool 显示文摘 | Antoun E N Dyksen J E Hiltebran D J | 1999 | AWWA1999，91，7： | 1 |
| 18 | Multifaceted beneficial effects of rhizosphere microorganisms on plant health and productivity显示文摘 | Tyler J. Avis Valérie Gravel Hani Antoun Russell J. Tweddell | 2008 | Soil Biology and Biochemistry2008，，7： | 1 |
| 19 | Self-aggregation of poly(methyl methacrylate)-block-poly(sulfonated glycidyl methacrylate) copolymers显示文摘 | GOHY J F ANTOUN S JEROME R | 2001 | Polymer2001，42，： | 1 |
| 20 | Control of greenhouse to- mato root rot in hydroponic systems, using plant- growth- promoting microorganisms 显示文摘 | GRAVEL V MARTINEZ C ANTOUN H | 2006 | Canadian Journal of Plant Patholo- gy2006，28，： | 1 |
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