|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Relationship between T-lymphocyte cytokine levels and sero-response to hepatitis B vaccines显示文摘AIM: To investigate the cellular defects by analyzing the (Th1/Th2) cytokine levels in vaccine responders and non-responders. METHODS: Peripheral blood mononuclear cell (PBMC) from responders and non-responders were stimulated with or with out recombinant HBsAg or PHA. Broad spectrum of cytokines viz (Th1) IFN-γ, IL-2, TNF-α, IL-12 and (Th2) IL-10, IL-4 were measured after in vitro stimulation with recombinant HBsAg and were compared with respective antibody titers. RESULTS: A significant decrease (P = 0.001) in Th1 and Th2 cytokines namely, IL-2, INF-γ, TNF-α and IL-10in non-responders was observed. The level of IL-4 was not significant between the three groups. Furthermore, despite a strong Th1 and Th2 cytokine response, the level of IL-12 was elevated in high-responders compared to other groups (P = 0.001) and demonstrated a positive correlation with anti-HBs titers and Th1 cytokine response. CONCLUSION: Our findings suggest that unrespon-siveness to recombinant hepatitis B vaccines (rHB) is multifactorial, including specific failure of antigen presentation or the lack of both T helper Th1 and Th2 response. | Vijayakumar Velu Shanmugam Saravanan Subhadra Nandakumar Esaki Muthu Shankar Appasamy Vengatesan Suresh Sakharam Jadhav Prasad Suryakant Kulkarni Sadras Panchatcharam Thyagarajan | 2008 | World Journal of Gastroenterology2008，14，22： | 22 |
| 2 | Relationship between male reproductive hormones, sperm DNA damage and markers of oxidative stress in infertility显示文摘 | Appasamy M Muttukrishna S Pizzey A R | 2007 | Reprod Biorned Online2007，14，2： | 1 |
| 3 | Hepatocyte growth factor, blood clearance, orgam uptake, and biliary excre- tion in normal and partially hepatectomized rats显示文摘 | APPASAMY R TANABE M MURASE N | 1993 | Lab Invest1993，68，： | 1 |
| 4 | Evaluation of the relationship between follicular fluid oxidative stress, ovarianhormones, and response to gonadotropin stimulation 显示文摘 | APPASAMY M JAUNIAUX E SERHAL P | 2008 | Fertility and Sterility2008，89，4： | 1 |
| 5 | Evaluation of the relationship between follicular fluid oxidative stress,ovarian hormones,and response to gonadotropin stimulation显示文摘 | Appasamy M Jauniaux E Serhal P | 2008 | Fertil Steril2008，89，4： | 1 |
| 6 | Water supply and waste disposal strategies for Madras 显示文摘 | Appasamy P | 1993 | Ambio1993，，22： | 1 |
| 7 | Relationship between male reproductive hormones, sperm DNA damage and markers of oxidative stress in infertility显示文摘 | Appasamy M Muttukrishna S Pizzey AR | 2007 | Reprod Biomed Online2007，14，2： | 1 |
| 8 | Relation- ship between male reproductive hormones, sperm DNA damage and markers of oxidative stress in infertility显示文摘 | Appasamy M Muttukrishna S Pizzey AR | 2007 | Reprod Biomed Online2007，14，2： | 1 |
| 9 | Relationship between male reproductive hormones, sperm DNA damage and markers of oxidative stress infertility 显示文摘 | Appasamy M MuttUkrishaa S Pizzey AR | 2007 | Reprod Biomed On- line2007，14，2： | 1 |
| 10 | Hepatic enzymes have a role in the diagnosis of hepatic injury after blunt abdominal trauma显示文摘 | Ker-Kan Tan Shieh-Ling Bang Appasamy Vijayan Ming-Terk Chiu | 2009 | Injury2009，，9： | 1 |
| 11 | Urbanization and integer oral competition for water显示文摘 | Ruth Meinzen Paul P Appasamy | 2001 | Urbanization and Water2001，2，： | 1 |
| 12 | Evaluation of the relationship between follicular fluid oxidative stress, ovarian hormones, and response to gonadotropin stimulation 显示文摘 | Appasamy M Jauniaux E Serhal P | 2008 | Fertil Steril2008，89，： | 1 |
| 13 | Regulation of interleukin 2-driven T-lymphocyte proliferation by prolactin 显示文摘 | Clevenger C V Russell D H Appasamy P M | 1990 | Proc Natl Acad Sci USA1990，87，： | 1 |
| 14 | Urbanization and intersectoral competition for water显示文摘 | Meinzen-Dick R Appasamy P P | 2001 | Urbanization and Water2001，，： | 1 |
| 15 | Structural,electrical and magnetic studies on Y-Fe-O system显示文摘The compounds of iron substituted yttrium oxide systems have been prepared for the importance in the field of magneto electric materials.The polycrystalline samples of Y2-xFexO3-y(x=0.1,0.2) were prepared by solid-state reaction method.The single-phase formation of these compounds was confirmed by X-ray diffraction studies.It was found that the samples crystallized in tetragonal phase and the lattice parameters were calculated as a=1.0559(7) nm,c=1.0832(9) nm for Y1.9Fe0.1O3-y and a=1.0545(6) nm,c=1.0841(8) nm for Y1.8Fe0.2O3-y.The lattice constant changed with the variation of Fe concentration,which indicated the incorporation of Fe3+ into the hosting Y2O3.The semi conducting nature of the prepared compounds was observed with the energy gap calculation from diffused reflectance spectroscopy(DRS) studies.The ferromagnetic nature of the prepared compounds was identified with vibrating sample magnetometer studies.This information were corroborated by the observation of the well broadened EPR lines in the electron paramagnetic resonance(EPR) spectra of the samples with a low Fe concentration,which manifested the onset of Fe-Fe exchange interaction in the prepared samples. | Anbarasu Venugopalan Manigandan Appasamy Sathiyakumar Saravanan Kaliyaperumal Kothandaraman Jayabalan Kothandaraman | 2009 | Journal of Rare Earths2009，27，6： | 1 |
| 16 | Sodium bicarbonate therapy for preven|ion of contrast-induced nephropathy:a systematic review and meta -analysis 显示文摘 | Navaneethan SD Singh S Appasamy S | 2009 | Am J Kidney Dis2009，53，4： | 1 |
| 17 | Sodiumbicarbonate therapy for prevention of contrast-inducednephropathy ? a systematic review and meta-analysis 显示文摘 | Navaneethan S D Singh S Appasamy S | 2009 | Am JKidney Dis2009，53，4： | 1 |
| 18 | Treatment strategies for genu recurvatum in adult patients with hemiparesis: a case series显示文摘 | Appasamy M De Witt ME Patel N | 2015 | PM R2015，7，2： | 1 |
| 19 | 2001, Urbanization and intersectoral competition for water 显示文摘 | RUTH M D APPASAMY P P | 2001 | Urbanization and Water2001，，9： | 1 |
| 20 | Sodium bicarbonate therapy for prevention of contrast-induced nephropathy:a systematic review and meta-analysis显示文摘 | Navaneethan SD Singh S Appasamy S | 2009 | Am J Kidney Dis2009，53，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员