| 2 | Understanding diarrhoeal diseases in response to climate variability and drought in Cape Town, South Africa: a mixed methods approach显示文摘BackgroundThe climate of southern Africa is expected to become hotter and drier with more frequent severe droughts and the incidence of diarrhoea to increase. From 2015 to 2018, Cape Town, South Africa, experienced a severe drought which resulted in extreme water conservation efforts. We aimed to gain a more holistic understanding of the relationship between diarrhoea in young children and climate variability in a system stressed by water scarcity.MethodsUsing a mixed-methods approach, we explored diarrhoeal disease incidence in children under 5 years between 2010 to 2019 in Cape Town, primarily in the public health system through routinely collected diarrhoeal incidence and weather station data. We developed a negative binomial regression model to understand the relationship between temperature, precipitation, and relative humidity on incidence of diarrhoea with dehydration. We conducted in-depth interviews with stakeholders in the fields of health, environment, and human development on perceptions around diarrhoea and health-related interventions both prior to and over the drought, and analysed them through the framework method.ResultsFrom diarrhoeal incidence data, the diarrhoea with dehydration incidence decreased over the decade studied, e.g. reduction of 64.7% in 2019 [95% confidence interval (CI): 5.5–7.2%] compared to 2010, with no increase during the severe drought period. Over the hot dry diarrhoeal season (November to May), the monthly diarrhoea with dehydration incidence increased by 7.4% (95% CI: 4.5–10.3%) per 1 °C increase in temperature and 2.6% (95% CI: 1.7–3.5%) per 1% increase in relative humidity in the unlagged model. Stakeholder interviews found that extensive and sustained diarrhoeal interventions were perceived to be responsible for the overall reduction in diarrhoeal incidence and mortality over the prior decade. During the drought, as diarrhoeal interventions were maintained, the expected increase in incidence in the public health sector did not occur.ConclusionsWe found that that diarrhoeal incidence has decreased over the last decade and that incidence is strongly influenced by local temperature and humidity, particularly over the hot dry season. While climate change and extreme weather events especially stress systems supporting vulnerable populations such as young children, maintaining strong and consistent public health interventions helps to reduce negative health impacts. | Tristan Taylor Lee Mohamed Aqiel Dalvie Martin Röösli Sonja Merten Marek Kwiatkowski Hassan Mahomed Neville Sweijd Guéladio Cissé | 2023 | Infectious Diseases of Poverty2023，12，4： | 0 |
| 3 | Cladding Modified Fiber Bragg Grating for Copper Ions Detection显示文摘This paper reports a fiber Bragg grating(FBG)as a biosensor.The FBGs were etched using a chemical agent,namely,hydrofluoric acid(HF).This implies the removal of some part of the cladding layer.Consequently,the evanescent field propagating out of the core will be closer to the environment and become more sensitive to the change in the surrounding.The proposed FBG sensor was utilized to detect toxic heavy metal ions aqueous medium namely,copper ions(Cu^(2+)).Two FBG sensors were etched with 20 and 40μm diameters and fabricated.The sensors were studied towards Cu^(2+)with different concentrations using wavelength shift as a result of the interaction between the evanescent field and copper ions.The FBG sensors showed a good response in terms of significant wavelength shift in corresponding to varying Cu2+concentrations when immersed in aqueous mediums.The sensors exhibited excellent repeatability towards Cu ions.The results demonstrate that the smaller FBG etching diameter,the better optical response in terms of wavelength and linearity. | Husam Abduldaem Mohammed Aqiel Almamori Ali A.Alwahib | 2021 | Semiconductor Science and Information Devices2021，3，2： | 0 |
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