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26篇 您的检索式:作者名="Aranaz"
    题名 作者 年代 出处 被引量
1Assesment of genetic markers for species differentiation within the Mycobacterium tuberculosis complex显示文摘Liebana E Aranaz A Francis B 1996J Clin Micro1996,34,:1
2Encapsulation of an Agrobacteri- um radiobacter extract containing d-hydantoinase and d-car- bamoylase activities into alginate-chitosan polyelectrolyte com-plexes preparation of the bioeatalyst 显示文摘Aranaz I Acosta N Heras A 2009J Mol Catalysis B Enzym2009,58,:1
3In vivo testing of mucus-permeating nanoparticles for oral insulin delivery using Caenorhabditis elegans as a model under hyperglycemic conditions显示文摘The aim was to evaluate the potential of mucus-permeating nanoparticles for the oral administration of insulin.These nanocarriers,based on the coating of zein nanoparticles with a polymer conjugate containing PEG,displayed a size of 260 nm with a negative surface charge and an insulin payload of 77 mg/mg.In intestinal pig mucus,the diffusivity of these nanoparticles(PPA-NPs)was found to be 20-fold higher than bare nanoparticles(NPs).These results were in line with the biodistribution study in rats,in which NPs remained trapped in the mucus,whereas PPA-NPs were able to cross this layer and reach the epithelium surface.The therapeutic effcacy was evaluated in Caenorhabditis elegans grown under high glucose conditions.In this model,worms treated with insulin-loaded in PPA-NPs displayed a longer lifespan than those treated with insulin free or nanoencapsulated in NPs.This finding was associated with a signifcant reduction in the formation of reactive oxygen species(ROS)as well as an important decrease in the glucose and fat content in worms.These effects would be related with the mucus-permeating ability of PPA-NPs that would facilitate the passage through the intestinal peritrophic-like dense layer of worms(similar to mucus)and,thus,the absorption of insulin.Ana LMartínez-López Carlos JGonzález-Navarro Paula Aranaz JoséLVizmanos Juan MIrache 2021Acta Pharmaceutica Sinica B2021,11,4:1
4Assessment of genetic markers for species differentiation within the Mycobacterium tuberculosis complex 显示文摘Liebam E Aranaz A Francis B 1996J Clin Microbiol1996,34,4:1
5Chitosan amphiphilic derivatives, chemistry and applications显示文摘Aranaz I 2010Curt Org Chem2010,14,3:1
6Functional characterization of chitin and chitosan显示文摘Jlnmaculada Aranaz Marian Mengibar l&uth Harris 2009CurrentChemical Bfology2009,3,20:1
7Functional characterization of chitin and chitosan显示文摘Aranaz l Meng bar M Harris R 0,,02:1
8Synthesis of p-hydroxyphenylglicine by cell extract from Agrobacterium radiobacter encapsulated in alginate capsules显示文摘Aranaz I Acosta N Heras A 2006Enzyme and Microbial Technology2006,39,:1
9Rapid identification and differentiation of mycobacterium avium subspecies paratuberculosis types by use of real-time PCR and high-resolution melt analysis of the MAP1506 locus显示文摘Castellanos E Aranaz A Buck JD 2010J Clin Microbiol2010,48,4:1
10Func- tional characterization of chitin and chitosan 显示文摘ARANAZ I MENGIBAR M HARRIS R 2009Cur- rent Chemical Biology2009,3,2:1
11Functional characterization of chitin and chitosan显示文摘Aranaz I Mengibar M Harris R 2009Current Chemical Biology2009,3,2:1
12Incidence of adverse events related to health carein Spain : results of the Spanish National Study of AdverseEvents 显示文摘Aranaz - Andr s J M Aibar - Rem n C Vitaller - MurilloJ 2008Journal of Epidemiology and CommunityHealth2008,62,12:1
13Functional characterization of chitin and chitosan 显示文摘ARANAZ I MENGIBAR M RUTH H 2009Current Chemical Biology2009,3,:1
14Incidence of adverse events related to health care in Spain : results of the Spanish National Study of Adverse Events 显示文摘Aranaz Andres J M Aibar Remon C Vitaller Murillo J 2008Journal of Epidemiology & Community Health2008,62,12:1
15Assessment of genetic markers for species differentiation within the Mycobacterium tuberculosis complex显示文摘Liehana E Aranaz A Francis B 1996J Clin Mierobiol1996,34,93:1
16Mycobacterium tuberculosis subsp caprae subsp nov: a taxonomic study of a new member of the Mycobacterium tuberculosis complex isolated from goats in Spain 显示文摘Aranaz A Li6bana E G6mez-Mampaso E 1999Int J Syst Bacteriol1999,493,:1
17Spacer oligonucleotide typing of Mycobacterium boris strains from cattle and other ani- mals: a tool for studying epidemiology of tuberculosis显示文摘Aranaz A Liebana E Mateos A 1996J Clin Mierobiol1996,34,11:1
18Genomic deletions suggest a phylogeny for the Mycobacterium tuberculosis complex显示文摘Mostowy S Cousins D Brinkman J Aranaz A Behr MA 2002J Infect Dis2002,186,1:1
19Assesment of genetic markers for species differentiation within the Mycobacterium tuberculosis complex 显示文摘Liebana E Aranaz A Francis B 1996J Clin Micro1996,34,:1
20Single nucleotide polymorphi- sms in the IS900 sequence of Mycobacterium avium subspparatuber- culosis are strain type specific 显示文摘Castellanos E Aranaz A Juan L 2009Joumal of Clinical MicrohMogy2009,47,:1
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