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| 1 | Validation of a new scoring system: Rapid assessment faecal incontinence score显示文摘AIM: To implement a quick and simple test- rapid assessment faecal incontinence score(RAFIS) and show its reliability and validity.METHODS: From March 2008 through March 2010, we evaluated a total of 261 consecutive patients, including 53 patients with faecal incontinence. Demographic and comorbidity information was collected. In a single visit, patients were administered the RAFIS. The results obtained with the new score were compared with those of both Wexner score and faecal incontinence quality of life scale(FIQL) questionnaire. The patient withoutinfluence of the surgeon completed the test. The role of surgeon was explaining the meaning of each section and how he had to fill. Reliability of the RAFIS score was measured using intra-observer agreement and Cronbach's alpha(internal consistency) coefficient. Multivariate analysis of the main components within the different scores was performed in order to determine whether all the scores measured the same factor and to conclude whether the information could be encompassed in a single factor. A sample size of 50 patients with faecal incontinence was estimated to be enough to detect a correlation of 0.55 or better at 5% level of significance with 80% power.RESULTS: We analysed the results obtained by 53 consecutive patients with faecal incontinence(median age 61.55 ± 12.49 years) in the three scoring systems. A total of 208 healthy volunteers(median age 58.41 ± 18.41 years) without faecal incontinence were included in the study as negative controls. Pearson's correlation coefficient between 'state' and 'leaks' was excellent(r = 0.92, P < 0.005). Internal consistency in the comparison of 'state' and 'leaks' yielded also excellent correlation(Cronbach's α = 0.93). Results in each score were compared using regression analysis and a correlation value of r = 0.98 was obtained with Wexner score. As regards FIQL questionnaire, the values of 'r ' for the different subscales of the questionnaire were: 'lifestyle' r =-0.87, 'coping/behaviour' r =-0.91, 'depression' r =-0.36 and 'embarrassment' r =-0.90,(P < 0.01). A multivariate analysis showed that all the scoring systems measured the same factor. A single factor may explain 80.84% of the variability of FI, so all the scoring systems measure the same factor. Patient's continence improves when RAFIS and Jorge-Wexner scores show low values and when the values obtained in the FIQL questionnaire are high.CONCLUSION: RAFIS is a valid and reliable tool to assess Faecal Incontinence. | Fernando de la Portilla Arantxa Calero-Lillo Rosa M Jiménez-Rodríguez Maria L Reyes Manuela Segovia-González María Victoria Maestre Ana M García-Cabrera | 2015 | World Journal of Gastrointestinal Surgery2015，7，9： | 5 |
| 2 | The effect of ultraviolet light on microbial inactivating and quality attributes of apple juice 显示文摘 | Irene M Camiti Izabela Palgan Arantxa Mufioz | 2012 | Food Bioproeess Technology2012，5，2： | 1 |
| 3 | Modeling and control of a wind turbine driven doubly fed induction generator显示文摘 | Arantxa Tapia Gerardo Tapia | 2003 | IEEE Transactions on Energy Conversion2003，18，2： | 1 |
| 4 | Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke 显示文摘 | Anna R Arantxa OA Jose AS | 2006 | Stroke2006，37，6： | 1 |
| 5 | Refractory hepatic encephalopathy in a patient with hypothyroidism: Another element in ammonia metabolism显示文摘Hepatic encephalopathy(HE) remains a diagnosis of exclusion due to the lack of specific signs and symptoms. Refractory HE is an uncommon but serious condition that requires the search of hidden precipitating events(i.e.,portosystemic shunt) and alternative diagnosis. Hypothyroidism shares clinical manifestations with HE and is usually considered within the differential diagnosis of HE. Here,we describe a patient with refractory HE who presented a large portosystemic shunt and post-ablative hypothyroidism. Her cognitive impairment,hyperammonaemia,electroencephalograph alterations,impaired neuropsychological performance,and magnetic resonance imaging and spectroscopy disturbances were highly suggestive of HE,paralleled the course of hypothyroidism and normalized after thyroid hormone replacement. There was no need for intervention over the portosystemic shunt. The case findings support that hypothyroidism may precipitate HE in cirrhotic patients by inducing hyperammonaemia and/or enhancing ammonia brain toxicity. This case led us to consider hypothyroidism not only in the differential diagnosis but also as a precipitating factor of HE. | Fernando Díaz-Fontenla Marta Castillo-Pradillo Arantxa Díaz-Gómez Luis Ibanez-Samaniego Pilar Gancedo Juan Adan Guzmán-de-Villoria Pilar Fernández-García Rafael Banares-Canizares Rita García-Martínez | 2017 | World Journal of Gastroenterology2017，23，28： | 1 |
| 6 | HIV-1 resistance to the gp41-dependent fusion inhibitor C-34显示文摘 | MERCEDES A U ARANTXA G | 2003 | Antiviral Research2003，59，： | 1 |
| 7 | Medina ATP-sensitive potassium channel regulates astrocytic gap junction permeability by a Ca^2+ independent mechanis 显示文摘 | ANA V ARANTXA T BEGONA G | 2000 | J Neurochem2000，27，： | 1 |
| 8 | Enhancing water repellence and mechanical properties of gelatin films by tannin addition显示文摘 | Cristina Pe(n)a Koro de la Caba Arantxa Eceiza | 2010 | Bioresource Technology2010，101，： | 1 |
| 9 | Bioche- mical markers of myocardial remodeling in hypertensive heart disease 显示文摘 | Arantxa Gonza'lez Begon-a Lo'pez Susana Ravassa | 2009 | Cardiovascular Research2009，81，： | 1 |
| 10 | Impact of selected combinations of non-thermal processing technologies on the quality of an apple and cranberry juice blend显示文摘 | Irene M. Caminiti Francesco Noci Arantxa Mu?oz Paul Whyte Desmond J. Morgan Denis A. Cronin James G. Lyng | 2010 | Food Chemistry2010，，4： | 1 |
| 11 | Severe respiratory disease concurrent with the circulation of H1N1 influenza显示文摘 | Gerardo Chowell Stefano M Bertozzi M Arantxa Colchero | 2009 | N Engl J Med2009，361，： | 1 |
| 12 | Gastric volvulus after sleeve gastrectomy for morbid obesity显示文摘 | Daniel Del Castillo Déjardin Fàtima Sabench Pereferrer Mercè Hernàndez Gonzàlez Santiago Blanco Blasco Arantxa Cabrera Vilanova | 2012 | Surgery2012，，： | 1 |
| 13 | Recovery of the hypothalamic-pituitaryadrenal response to stress 显示文摘 | ARANTXA G OCTAVI M | 2000 | Neuroendocrinology2000，72，1： | 1 |
| 14 | Models for Gaze Tracking Systems 显示文摘 | Arantxa Villanueva Rafael Cabeza | 2007 | EURASIP Journal on Image and Video Processing (S1687-5176)2007，2007，4： | 1 |
| 15 | CEO compensation:Trends, market changes, and regulation显示文摘 | Jarque Arantxa | 2008 | Economic Quarterly2008，94，2： | 1 |
| 16 | Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke显示文摘 | Anna R Arantxa OA Jose AS | 2006 | Stroke2006，37，： | 1 |
| 17 | A randomized phase 2b study of peginterferon lambda-1a for the treatment of chronic HCV infection显示文摘 | Andrew J. Muir Sanjeev Arora Gregory Everson Robert Flisiak Jacob George Reem Ghalib Stuart C. Gordon Todd Gray Susan Greenbloom Tarek Hassanein Jan Hillson Maria Arantxa Horga Ira M. Jacobson Lennox Jeffers Kris V. Kowdley Eric Lawitz Stefan Lueth Maribe | 2014 | Journal of Hepatology2014，，： | 1 |
| 18 | Increased Brain Expression of Matrix Metalloproteinase-9 After Ischemic and Hemorrhagic Human Stroke显示文摘 | Anna Rosell Arantxa Ortega-Aznar José Alvarez-Sab′n Israel Fernández-Cadenas Marc Ribó Carlos A. Molina Eng H. Lo Joan Montaner | 2006 | Stroke2006，，： | 1 |
| 19 | In Vitro and In VivoActivation of Astrocytes by Amyloid-β is Potentiated by Pro-Oxidant Agents显示文摘 | Silvia Garcí a-Matas Nú ria de Vera Arantxa Ortega Aznar Josep M. Marimon Albert Adell Anna M. Planas Rosa Cristò fol Coral Sanfeliu | 2009 | Journal of Alzheimer’s Disease2009，，： | 1 |
| 20 | Impact of selected combinations of non-thermal processingtechnologies on the quality of an apple and cranberry juice blend显示文摘 | Irene M Caminiti Francesco Noci Arantxa Mufioz | 2011 | Food Chemistry2011，124，： | 1 |
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