| 1 | Isolation and in vivo hep-atoprotective activity of Melothria heterophylla(Lour.) Cogn.against chemically induced liver injuries in rats显示文摘Objective:To investigate hepatoprotective activity of ethanol extract of Melothria heterophyila Lour Cogn.(EEMH) against CCl4-induced hepatic damage in rats.Methods:β-sitosterol was isolated by column chromatography and characterized spectroscopically.Two different doses(200 and 400 mg/kg bw) of EEMH were administered orally in alternate days.The hepatoprotective activity was studied in liver by measuring biochemical parameters such as serum aspartate amino transferase(AST),alanine amino transferase(ALT),alkaline phosphatase(ALP),total protein and total bilirubin.Lipid peroxidation product and different antioxidant enzyme activities were assessed in liver homogenate.Results:EEMH reduced all biochemical parameters and lipid peroxidation,as well as it increased the antioxidant enzyme activities in comparison with silymarin.The protective effect of the extract on CCl4 induced damage was confirmed by histopathological examination of the liver.Conclusions:This result strongly supports the protective effect of EEMH against acute liver injury,and may be attributed to its antioxidative activity. | Arijit Mondal Tapan Kumar Maity Dilipkumar Pal Santanu Sannigrahi Jagadish Singh | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，8： | 2 |
| 3 | Transformation and risk assessment of the East Kolkata Wetlands (India)using fuzzy MCDM method and geospatial technology显示文摘The East Kolkata Wetlands (EKW) is located on the eastern periphery of the city of Kolkata and extends up to theBidyadhari-Matla River confluence. It is a Ramsar Site and acts as an absorber basin for a large number of con-taminants drained from Kolkata. Agricultural lands, sewage-fed fisheries, garbage dumping fields, horticulture,and built-up areas are included in this protected area, that covers approximately 125 km2. It reveals that climatechange reduces the variety of wetland ecosystem services and increases socio-economic vulnerability and eco-nomic stress. The human encroachment, reclamation of land for agriculture, aquaculture, and urban expansion inand around Kolkata has recently adversely threatened the EKW. The remotely sensed data, socio-economic data,and responses of inhabitants have been used to analyse the EKW’s risk and vulnerability. We employed geospatialanalysis by using the Multi-Criteria Decision Making (MCDM) method using nine risk factors. An in-depth analysisof the EKW using geospatial techniques and the Fuzzy Analytic Hierarchy Process (FAHP) helped to understandthe EKW transformations through vulnerability and risk analysis. The results show that the transformation of thewetland to aquaculture, eutrophication and pollution, road proximity, waste dumping, population density, andgrowth are the main factors for the deteriorating health, quality, and environment of the EKW. It also reveals thatquantitative and qualitative evaluations of ecosystem services, wetland degradation, transformation, and cause-effect rapport should be periodically assessed using scientific methods like FAHP, RS, GIS to formulate resilient,integrated plans and strategy for the sustainable management of the EKW. | Biraj Kanti Mondal Suchitra Kumari Arijit Ghosh Prabuddh Kumar Mishra | 2022 | Geography and Sustainability2022，3，3： | 0 |
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