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21篇 您的检索式:作者名="Arjamaa"
    题名 作者 年代 出处 被引量
1Physiology of natriuretic peptides: The volume overload hypothesis revisited显示文摘The discovery of the natriuretic peptide system in the early 1980s aroused great interest among clinical cardiologists. The heart was not a mechanical pump alone, but also an endocrine organ that had powerful effects on blood circulation. Natriuretic peptides caused both natriuresis and diuresis, and they responded to a volume overload which caused either stretch or pressure on the heart. As a result, the findings led to the conclusion that the human body had a hormone with effects similar to those of a drug which treats high blood pressure. Later, it became evident that the volume contraction was fortified by extrarenal plasma shift. Here, a hypothesis is presented in which the role of natriuretic peptides is to regulate oxygen transport as the volume contraction leads to hemoconcentration with an increased oxygen-carrying capacity. Wall stress, either chemical or mechanical, changes the oxygen gradient of the myocardium and affects the diffusion of oxygen within a myocyte. In support of this hypothesis, hypoxia-response elements have been found in both the atrial natriuretic peptide and the brain natriuretic peptide genes.Olli Arjamaa 2014World Journal of Cardiology2014,6,1:8
2Oxygen-dependent diseases in the reti- na: role of hypoxia-inducible factors 显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Res2006,83,3:1
3Oxygen and natriuretic peptide secretion from the heart显示文摘Olli Arjamaa Mikko Nikinmaa 2012International Journal of Cardiology2012,,:1
4Oxygen-dependent diseases in the retina:Role of hypoxia-inducible factors显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Res2006,83,3:1
5Localization of Salmon Cardiac Peptide (sCP) in the Heart of Salmon ( Salmo salar L.)显示文摘Olli Arjamaa Raija Sormunen Veli-Pekka Lehto Olli Vuolteenaho 2000General and Comparative Endocrinology2000,,3:1
6Oxygen-dependent diseases in the retina: Role of hypoxia-inducible factors显示文摘Olli Arjamaa Mikko Nikinmaa 2006Experimental Eye Research2006,,3:1
7Oxygen-dependent diseases in the retina:role of hypoxia-inducible factors 显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Res2006,83,3:1
8Oxygen-dependent diseases in the retina:Role of hypoxia inducible factors显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Res2006,83,3:1
9Atrial natfiuretic peptide (ANP) in rat gastrointestinal tract 显示文摘Vuoheenaho O Arjamaa O Vakkuri O 1988FEBS Letters1988,233,1:1
10Atrial nutriuretic peptide (ANP)in rat gastrointestinal tract 显示文摘Vuolteenaho O Arjamaa O Vakkuri O 1988J FEBS Lett1988,233,:1
11Atrial natriuretic peptide(ANP)in rat gastrointestinal tract显示文摘 ARJAMAA O VAKKURI O 1988FEBS Lett1988,233,:1
12Hypoxia regulates the natriuretic peptide system 显示文摘Arjamaa O Nikinmaa M 2011Int J Physiol Pathophysiol Pharmacol2011,3,3:1
13Oxygen-dependent diseases in the reti- na: role of hypoxia-inducible factors 显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Res2006,83,3:1
14Oxygen-depandent diseases in the retina:role of hypoxia-inducible factors显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Bes2006,83,3:1
15Oxygen-dependent diseases in the retina : role of hypoxia-indueible factors 显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Res2006,83,3:1
16Oxygen-dependent diseases in the retina: role of hypoxia-inducible factors 显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Res2006,83,3:1
17Regulatory role of HIF-1 alpha in the pathogenesis of age-related macular degeneration (AMD) 显示文摘Arjamaa O Nildnmaa M Salminen A Kaarniranta K 2009Ageing Res Rev2009,8,4:1
18Oxygendependent diseases in the retina: Role of hypoxiainducible factors 显示文摘Arjamaa O Nikinmaa M 2006Exp Eye Res2006,83,3:1
19Increased IL- 6 levels are not related to NF - κB or HIF - 1 a transcription factors activity in the vitreous of proliferative diabetic retinopathy 显示文摘Arjamaa O Ptill~ nen M Kinnunen K 2011J Diabetes Com- plicat2011,25,6:1
20Oxygen-dependent diseases in the retina:role of hypoxia-inducible factors显示文摘Arjamaa O Nikinmaa M 0,,03:1
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