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| 1 | Cervical spine fractures in osteopetrosis:a case report and review of the literature显示文摘While management of appendicular fractures has been well described in the setting of osteopetrosis, there is limited information on managing fractures of the axial spine. Here we present an osteopetrotic patient with multiple traumatic multiple, comminuted, unstable cervical spinal fractures managed with non-operative stabilization, and provide a review of the pathophysiology, genetic characteristics, and special considerations that must be explored when determining operative versus non-operative management of spinal injury in osteopetrosis. A PubMed query was performed for English articles in the literature published up to June 2016, and used the following search terms alone and in combination: 'osteopetrosis', 'spine', 'fractures', 'osteoclasts', and 'operative management'. Within four months after initial injury, treatment with halo vest allowed for adequate healing. The patient was asymptomatic with cervical spine dynamic radiographs confirming stability at four months. On four-year follow up examination, the patient remained without neck pain, and CT scan demonstrated partially sclerotic fracture lines with appropriate anatomical alignment. In conclusion, external halo stabilization may be an effective option for treatment of multiple unstable acute traumatic cervical spine fractures in patients with osteopetrosis. Given the challenge of surgical stabilization in osteopetrosis, further research is necessary to elucidate the optimal form of treatment in this select patient population. | Arjang Ahmadpour Amir Goodarzi Darrin J.Lee Ripul R.Panchal Kee D.Kim | 2018 | The Journal of Biomedical Research2018，32，1： | 3 |
| 2 | Histopathological characteristics and causes of kidney graft failure in the current era of immunosuppression显示文摘BACKGROUND The histopathological findings on the failing kidney allograft in the modern era is not well studied. In this study, we present our experience working with kidney transplant recipients with graft failure within one year of the biopsy.AIM To report the histopathological characteristics of failed kidney allografts in the current era of immunosuppression based on the time after transplant, cause of the end-stage renal disease and induction immunosuppressive medications.METHODS In a single-center observational study, we characterized the histopathological findings of allograft biopsies in kidney transplant recipients with graft failure within one year after the biopsy.RESULTS We identified 329 patients with graft failure that met the selection criteria between January 1, 2006 and December 31, 2016. The three most common biopsy findings were interstitial fibrosis and tubular atrophy(IFTA, 53%), acute rejection (AR, 43%) and transplant glomerulopathy(TG, 33%). Similarly, the three most common causes of graft failure based on the primary diagnosis were AR(40%),TG(17%), and IFTA(13%). Most grafts failed within two years of post-transplant(36%). Subsequently, approximately 10%-15% of grafts failed every two years: >2-4 years(16%), > 4-6 years(13%), > 6-8 years(11%), > 8-10 years(9%) and > 10 years(16%). AR was the most common cause of graft failure in the first six years(48%), whereas TG was the most prevalent cause of graft failure after 6 years(32%) of transplant.CONCLUSION In the current era of immunosuppression, AR is still the most common cause of early graft failure, while TG is the most prevalent cause of late graft failure. | Sandesh Parajuli Fahad Aziz Neetika Garg Sarah E Panzer Emily Joachim Brenda Muth Maha Mohamed Justin Blazel Weixiong Zhong Brad C Astor Didier A Mandelbrot Arjang Djamali | 2019 | World Journal of Transplantation2019，9，6： | 2 |
| 3 | The impact of hepatitis C virus donor and recipient status on long‐term kidney transplant outcomes: University of Wisconsin experience显示文摘 | Neeraj Singh Nikole Neidlinger Arjang Djamali Glen Leverson Barbara Voss Hans W. Sollinger John D. Pirsch | 2012 | Clinical Transplantation2012，，5： | 1 |
| 4 | Anticoagulation for prosthetic heart valves during pregnancy:is low-molecalar heparin an alternative显示文摘 | Rainer GL Stefan F Arjang R | 2002 | Europ J Cardio Thoracic Surg2002，21，： | 1 |
| 5 | Modeling and simulation of luminescence detection platforms 显示文摘 | Khaled Salama Helmy Eltoukhy Arjang Hassibi etc | 2004 | biosensors and bioelectronics2004，，6： | 1 |
| 6 | Intra-vital Fluorescence Microscopy for Intra-myocardial Graft Detection Following Cell Transplantation显示文摘 | Arjang Ruhparwar Theo Kofidis Nicole Ruebesamen Matthias Karck Axel Haverich Ulrich Martin | 2005 | The International Journal of Cardiovascular Imaging2005，，5： | 1 |
| 7 | The role of complement in the patho-genesis of renal ischemia-reperfusion injury and fibrosis显示文摘 | Juan SD Arjang D Luis AF | 2014 | Fibro- genesis and Tissue Repair2014，7，： | 1 |
| 8 | Role of novel biomarkers in kidney transplantation显示文摘Clinical application of biomarkers is an integral component of transplant care.Clinicians and scientists alike are in search of better biomarkers than the current serologic(serum creatinine,donor-specific antibodies),urine-derived(urinalysis,urine protein),and histologic ones we now use.The science behind recent biomarker discovery spans across multiple molecular biologic disciplines,including transcriptomics,proteomics,and metabolomics.Innovative methodology and integration of basic and clinical approaches have allowed researchers to unearth molecular phenomena preceding clinical disease.Biomarkers can be classified in several ways.In this review,we have classified them via their origin and outcome:Primarily immunologic,i.e.,representative of immune regulation and dysfunction and non-immunologic,pertaining to delayed graft function,cardiovascular events/mortality,infection,malignancy,posttransplant diabetes,graft,and patient survival.Novel biomarker uses to guide the diagnosis and management of transplant-related outcomes is a promising area of research.However,the use of biomarkers to predict outcomes after kidney transplantation is not well studied.In this review,we summarize the recent studies illustrating biomarker use and transplant outcomes. | Kurtis J Swanson Fahad Aziz Neetika Garg Maha Mohamed Didier Mandelbrot Arjang Djamali Sandesh Parajuli | 2020 | World Journal of Transplantation2020，10，9： | 1 |
| 9 | Pretransplant Donor-Specific Antibodies Detected by Single-Antigen Bead Flow Cytometry Are Associated With Inferior Kidney Transplant Outcomes显示文摘 | Neeraj Singh Arjang Djamali David Lorentzen John D. Pirsch Glen Leverson Nikole Neidlinger Barbara Voss Jose R. Torrealba R. Michael Hofmann Jon Odorico Luis A. Fernandez Hans W. Sollinger Milagros Samaniego | 2010 | Transplantation2010，，10： | 1 |
| 10 | Anticoagulationfor prosthetic heart valves during pregnancy ; is low- melecalar beparin an altermative Europ显示文摘 | Rainer GL Stefan F Arjang R | 2002 | J Canlio Tho- racic Surg2002，21，： | 1 |
| 11 | Effect of Tillage and Planting Methods on the Soil Properties, Grain Drill Performance, and Wheat Yield显示文摘 | Sadegh Afzalinia Ali Khosravani Arjang Javadi Dadgar Mohammadi Seyyed Mansour Alavimanesh | 2012 | Journal of Agricultural Science and Technology(A)2012，2，4： | 1 |
| 12 | Gastric tubes and airway management in patients at risk of aspiration: history, current concepts, and proposal of an algorithm 显示文摘 | M R SALEM ARJANG K SIAVOSH S | 2014 | AnesthAnalg2014，118，3： | 1 |
| 13 | Blood oxygen level-dependent and perfusion magnetic resonance imaging: detecting differences in oxygen bioavailability and blood flow in transplanted kidneys显示文摘 | Elizabeth A. Sadowski Arjang Djamali Andrew L. Wentland Rebecca Muehrer Bryan N. Becker Thomas M. Grist Sean B. Fain | 2010 | Magnetic Resonance Imaging2010，，1： | 1 |
| 14 | Interface gap size of manually and CAD/CAM-manufactured ceramic inlays/onlays in vitro显示文摘 | Simon Addi Arjang Hedayati-Khams Amin Poya | 2002 | Journal Dentistry2002，30，1： | 1 |
| 15 | Intrathymic injection of anti-Fas monoclonal antibody prolongs murine non-vascularized cardiac allograft survival显示文摘 | Arjang Djamali Kenneth R. Waller Jonathan McAnulty Debra Hullett Bryan N. Becker Jon S. Odorico | 2004 | Transplant International2004，，6： | 1 |
| 16 | Enrichment of cardiac pacemaker-like cells: neuregulin-1 and cyclic AMP increase I f -current density and connexin 40 mRNA levels in fetal cardiomyocytes显示文摘 | Arjang Ruhparwar Fikret Er Ulrich Martin Kristin Radke Ina Gruh Michael Niehaus Matthias Karck Axel Haverich Uta C. Hoppe | 2007 | Medical & Biological Engineering & Computing2007，，2： | 1 |
| 17 | Epithelial-to-mesenchymal transition and chronic allograft tubulointerstitial fibrosis显示文摘 | Surmeet Bedi Aparna Vidyasagar Arjang Djamali | 2008 | Transplantation Reviews2008，，1： | 1 |
| 18 | Portal Application of Human Unrestricted Somatic Stem Cells to Support Hepatic Regeneration after Portal Embolization and Tumor Surgery显示文摘 | Ali Ghodsizad Bridget N. Fahy Simon Waclawczyk Stefanie Liedtke Jose M. Gonzalez Berjon Roberto Barrios Arianeb Mehrabi Matthias Karck Arjang Ruhparwar Gesine K?gler | 2012 | ASAIO Journal2012，，3： | 1 |
| 19 | Predictive Risk Factors for Patients With Cirrhosis Undergoing Heart Surgery显示文摘 | Rawa Arif Philipp Seppelt Simon Schwill Dubravka Kojic Ali Ghodsizad Arjang Ruhparwar Matthias Karck Klaus Kallenbach | 2012 | The Annals of Thoracic Surgery2012，，6： | 1 |
| 20 | Epithelial-to- mesenchymal transition and chronic allograft tubulointerstitial fibrosis 显示文摘 | Surmeet B Aparna V I Arjang D | 2008 | Transplantation Reviews2008，22，1： | 1 |
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