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9篇 您的检索式:作者名="Armin Blesch"
    题名 作者 年代 出处 被引量
1Targeted tissue engineering:hydrogels with linear capillary channels for axonal regeneration after spinal cord injury显示文摘Spinal cord injury(SCI)frequently results in the permanent loss of function below the level of injury due to the failure of axonal regeneration in the adult mammalian central nervous system(CNS).The limited intrinsic growth capacity of adult neurons,a lack of growth-promoting factors and the multifactorial inhibitory microenvironment around the lesion site contribute to the lack ofShengwen Liu Armin Blesch 2018Neural Regeneration Research2018,13,4:2
2A neurovascular niche for neurogenesis after stroke显示文摘John J Ohab Sheila Fleming Armin Blesch 2006J Neurosci2006,26,13:1
3Brain-Derived Neurotrophic Factor Gene Transfer With Adeno-Associated Viral and Lentiviral Vectors Prevents Rubrospinal Neuronal Atrophy and Stimulates Regeneration-Associated Gene Expression After Acute Cervical Spinal Cord Injury显示文摘Brian K. Kwon Jie Liu Clarrie Lam Ward Plunet Loren W. Oschipok William Hauswirth Adriana Di Polo Armin Blesch Wolfram Tetzlaff 2007Spine2007,,11:1
4Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer’s disease显示文摘Mark H. Tuszynski Armin Blesch 2004Progress in Brain Research2004,,:1
5Induction of bone marrow stromal cells to neurons:differentiation,transdifferentiation,or artifact?显示文摘Paul Lu Armin Blesch Mark H 2004J Neurosci Res2004,77,:1
6Neural stem cells for spinal cord repair显示文摘Beatrice Sandner Peter Prang Francisco J. Rivera Ludwig Aigner Armin Blesch Norbert Weidner 2012Cell and Tissue Research2012,,1:1
7Alginate hydrogel cross-linked by Ca^(2+)to promote spinal cord neural stem/progenitor cell differentiation and functional recovery after a spinal cord injuryhh显示文摘Alginate capillary hydrogels seeded with differentiated cells can fill the lesion cavity and promote axonal regeneration after grafting into the injured spinal cord.Neural stem/progenitor cells(NSPCs)can potentially repair the spinal cord;however,effects of alginate hydrogels(AHs)on NSPCs remain unknown.In this study,we fabricated AHs cross-linked by Ca^(2+)and seeded hydrogels with rat embryonic day 14 NSPCs.Immunocytochemistry and electron microscopy show that NSPCs survive,proliferate and differentiate into neurons in vitro within the capillaries.After transplantation into an acute T8 complete spinal cord transection site in adult rats,approximately one-third(38.3%)of grafted cells survive and differentiate into neurons(40.7%),astrocytes(26.6%)and oligodendrocytes(28.4%)at 8weeks post-grafting.NSPCs promote the growth of host axons within the capillaries in a time-dependent manner.Host axons make synapse-like contacts with NSPC-derived neurons within the hydrogel channels,and graft-derived axons extend into the host white and gray matter making putative synapses.This is paralleled by improved electrophysiological conductivity across the lesion and partial hindlimb locomotor recovery.Jun Zhou Yaqi Wu Zhijian Tang Kaipeng Zou Juan Chen Zuowei Lei Xueyan Wan Yanchao Liu Huaqiu Zhang Yu Wang Armin Blesch Ting Lei Shengwen Liu 2022Regenerative Biomaterials2022,9,1:1
8Motor Axonal Regeneration after Partial and Complete Spinal Cord Transection显示文摘Paul Lu Armin Blesch Lori Graham Yaozhi Wang Ramsey Samara Karla Banos Verena Haringer Leif Havton Nina Weishaupt David Bennett Karim Fouad Mark H. Tuszynski 2012Journal of Neuroscience2012,,24:1
9Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer显示文摘Armin Blesch 2003Methods2003,,2:1
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