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| 1 | Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed. | Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost | 2019 | Stroke & Vascular Neurology2019，4，4： | 2 |
| 2 | Increased Risk of Both Ulcerative Colitis and Crohn’s Disease in a Population Suffering from COPD显示文摘 | Anders Ekbom Lena Brandt Fredrik Granath Claes-G?ran L?fdahl Arne Egesten | 2008 | Lung2008，，3： | 2 |
| 3 | Cost- effectiveness of linezolid versus vancomycin in mechanical ventilation-associated nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus显示文摘 | Machado A R L Arns C C Follador W | 2005 | Braz J lnfect Dis2005，9，3： | 1 |
| 4 | Organizing flexibility: the flexiblefirm in a new century显示文摘 | ARNE L KALLEBERG | 2001 | British Journal of Industrial Rela-tions2001，，12： | 1 |
| 5 | Three dimensional imaging of multiphase flow in porous media显示文摘 | Turner M L Knung L Arns C H | 2004 | Physica A2004，33，9： | 1 |
| 6 | Molecular characterizat-ion of Brazilian avian pneumovirus isolates using reverse transcription-polymerase chain reaction,restriction endonuclease analysis and sequencing of a G gene fragment显示文摘 | Dani M A C Arns C W Durigon E L | 1999 | Avian Pathol1999，28，： | 1 |
| 7 | Predictability of intraocular lens power calculation in the treatment of cataract in children显示文摘 | Lesueur L Arne JT Chapotot E | 1999 | J Fr Ophthalmol1999，22，2： | 1 |
| 8 | Intravenous immunoglobulin does not reduce left ventricular remodeling in patients with myocardial dysfunction during hospitalization after acute myocardial infarction显示文摘 | Lars Gullestad Stein ?rn Kenneth Dickstein Christian Eek Thor Edvardsen Svend Aakhus Erik T. Askevold Annika Michelsen Bj?rn Bendz Rita Sk?rdal Hans-J?rgen Smith Arne Yndestad Thor Ueland P?l Aukrust | 2012 | International Journal of Cardiology2012，，： | 1 |
| 9 | Heteroplasmy in the mtDNA control region of sturgeon(Acipenser,Huso and Scaphirhynchus) 显示文摘 | Arne L Bernie M Lutz D | 2000 | Genetics2000，156，： | 1 |
| 10 | Vanadia catalysts on anatase, rutile, and TiO2(B) for the ammoxidation of toluene: an ESR and high-resolution electron microscopy characterization显示文摘 | Mehri Sanati Reine L Wallenberg Arne Andersson Susan Jansen Yanping T | 1991 | Journal of Catalysis1991，132，1： | 1 |
| 11 | Glutathione S-Trans- ferase Omega 1 variation does not influence age at onset of Huntington's discase 显示文摘 | Arning L Jagiello P Wieezorek S | 2004 | BMCMedGenet2004，5，： | 1 |
| 12 | Three-dimensional imaging of multiphase flow in porous media显示文摘 | Turner M L Knüfing L Arns C H | 2004 | Physica A2004，339，12： | 1 |
| 13 | T he pharmacokinetics of continuous infusion pralidoxime in children with organophosphate poisoning显示文摘 | Sc hex nayder S James L P Ke arn s G L | 1998 | J Toxicol Clin Toxicol1998，36，6： | 1 |
| 14 | Preparation and assay of mammali- an thioredoxin and thioredoxin reductase 显示文摘 | Arne' r ES Zhong L Holmgren A | 1999 | Meth Enzymol1999，300，： | 1 |
| 15 | Development of the as-cast microstructure in magnesium-aluminium alloys 显示文摘 | ARNE K D YOUNG C L MARK D N | 2001 | Journal of Light Metals2001，，1： | 1 |
| 16 | Comparison of in-house PCR, rapid ELISA and NASBA technology for the detection of respiratory syncytial virus in clinical specimen显示文摘 | Ramona L T Arne S AndreasM | 2008 | J Clin Virol2008，41，2： | 1 |
| 17 | Acid deposition and its effects in China: an overview显示文摘 | Thorjφrn L Hans M S Arne S | 1999 | Environmental Science Policy1999，，2： | 1 |
| 18 | Acid deposition and its effects in China: An overview显示文摘 | Thorjorn L Hans M S Arne S | 1999 | Environmental Science and Policy1999，2，1： | 1 |
| 19 | A signaling network reciprocally regulates genes associated with acute infection and chronic persistence in Pseudomonas aeruginosa 显示文摘 | Andrew L G Bridget K Arne R | 2004 | Developmental Cell2004，7，： | 1 |
| 20 | Enzyme conversion immunoassay for determining total homocysteine in plasma or serum显示文摘 | Arne L F Ingrid A | 1998 | Clin Chem1998，44，2： | 1 |
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