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| 1 | Reduction of ischemia reperfusion injury after liver resection and hepatic inflow occlusion by α-lipoic acid in humans显示文摘AIM: To evaluate the protective effects of precondition- ing by α-lipoic acid (LA) in patients undergoing hepatic resection under inflow occlusion of the liver. METHODS: Twenty-four patients undergoing liver re- section for various reasons either received 600 mg LA or NaCl 15 min before transection performed under inflow occlusion of the liver. Blood samples and liver wedge bi- opsy samples were obtained after opening of the abdo- men immediately after inflow occlusion of the liver, and 30 min after the end of inflow occlusion of the liver. RESULTS: Serum levels of aspartate transferase and alanine transferase were reduced at all time points in patients who received LA in comparison to those who received NaCL. This was accompanied by reduced histo- morphological features of oncosis. We observed TUNEL- positive hepatocytes in the livers of the untreated patients, especially after 30 min of ischemia. LA attenu- ated this increase of TUNEL-positive hepatocytes. Under preconditioning with LA, ATP content was significantly enhanced after 30 min of ischemia and after 30 min of reperfusion. CONCLUSION: This is the first report on the poten- tial for LA reducing ischemia/reperfusion injury (IRI) of the liver in humans who were undergoing liver surgery. Beside its simple and rapid application, side effects did not occur. LA might therefore represent a new strategy against hepatic IRI in humans. | Fritz Dünschede Kirsten Erbes Achim Kircher Stefanie Westermann Joachim Seifert Arno Schad Kempski Oliver Alexandra K Kiemer Junginger Theodor | 2006 | World Journal of Gastroenterology2006，12，42： | 6 |
| 2 | Analysis of PSLQ, an integer relation finding algorithm显示文摘 | Ferguson H R P Bailey D H Arno S | 1999 | Math Comput1999，68，225： | 1 |
| 3 | A practical, efficient, and atom economic alternative to the Witting and Horner- Wadsworth-Emmons reactions for the synthesis of (E)-α,β-unsaturated esters from aldehydes显示文摘 | Benjamin L Arno D Maria T | 2006 | Tetrahedron2006，，： | 1 |
| 4 | Heart displacement during offpump CABG:how well is it tolerated显示文摘 | Arno PN Jan D Erik WLJ | 2000 | Ann Thorac Surg2000，70，： | 1 |
| 5 | Non-destructive detection of hollow heart in potatoes using hyperspectral imaging显示文摘 | Angel D N Arno F Pilar C | 2011 | Image Analysis and Processing2011，6855，1： | 1 |
| 6 | Does universal newborn hearing screening identify all children with GJB2 (Connexin 26) deafness? Pene trance of GJB2 deafness 显示文摘 | NORRIS V W ARNOS K S HANKS W D | 2006 | Ear Hear2006，27，： | 1 |
| 7 | Rural-urban differences in Austrian suicides显示文摘 | Nestor D Kapusta Arno Z | 2008 | Social Psychiatry and Psychiatric Epidemiology2008，43，： | 1 |
| 8 | Does universal newborn hearing screening identify all childern with GJB2(Connexin 26)deafness Penetrance of GJB2deafness显示文摘 | NORRIS V W ARNOS K S HANKS W D | 2006 | Ear Ear Hear2006，27，： | 1 |
| 9 | Rare diseases, drug development, and AIDS: the impact of the Orphan Drug Act显示文摘 | Arno P S Karen B Michael D | 1995 | The Milbank Quarterly1995，，： | 1 |
| 10 | Mass spectrometric contributions to the practice of phosphorylation site mapping through 2003 : a literature review 显示文摘 | LOYET K M STULTS J T ARNO' | 2005 | Mol Ceil Proteomics2005，4，： | 1 |
| 11 | Retrospective analysis of total knee arthroplasty cases for visual,histological,and clinical eligibility of unicompartmental knee arthroplasties显示文摘 | Arno S Maffei D Walker PS | | 0，，： | 1 |
| 12 | Detection of antigens recognized by a novel monoclonal antibody in tissue and serum from patients with breast cancer 显示文摘 | Iacobelli S Arno E D'Orazio-A | 1986 | Cancer Res1986，46，6： | 1 |
| 13 | Biological control of Bemisia tabaci using predators and parasitoids显示文摘 | Gerling D Alomar O Arno J | 2001 | Crop Protection2001，20，9： | 1 |
| 14 | Does universal newborn hearing screening identify all children with GJB2(Connexin 26)deafness?Penetrance of GJB2deafness显示文摘 | NORRIS V W ARNOS K S HANKS W D | 2006 | Ear Hear2006，27，： | 1 |
| 15 | Non destructive detection of hollow heart in potatoes using hyperspectral imaging显示文摘 | Angel D N Arno F Pilaf C | 2011 | Image A nalysis and Processing2011，6855，18： | 1 |
| 16 | Biological control of Bemisia tabaci using predators and parasitoids显示文摘 | GERLING D ALOMAR O ARNO J | 2001 | Crop Protection2001，20，： | 1 |
| 17 | A practical,efficient,and atom economic alternative to the Wittig and Horner-Wadsworth-Emmons reactions for the synthesis of (E)-α,β-unsaturated esters from aldehydes显示文摘 | BENJAMIN L ARNO D MARIA T | | 0，，2： | 1 |
| 18 | Microenvironment produced by acute myeloid leukemia cells prevents T cell activation and proliferation by inhibition of NF-kappaB, c-Myc, andp Rb pathwaysl显示文摘 | Buggins AG Milojkovic D Arno MJ | 2001 | Journal of Immunology2001，167，10： | 1 |
| 19 | Microenvironment produced by acute myeloid leukemia cells prevents T cell activation and proliferation by inhibition of NF-B,c-Myc,and pRb pathways显示文摘 | BUGGINS A G MILOJKOVIC D ARNO M J | 2001 | J Immunol2001，167，10： | 1 |
| 20 | A practical efficient, and atom economic al- ternative to the Wittig and Horner-Wadsworth-Emmons reactions for the synthesis of(E)-a, fl-unsaturated esters from aldehydes 显示文摘 | Benjamin L Arno D | 2006 | Tetrahedron2006，62，3： | 1 |
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