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4篇 您的检索式：作者名="Arum Han"

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		题名	作者	年代	出处	被引量
	1	Development and characterization of microfluidic devices and systems for magnetic bead-based biochemical detection显示文摘	Jin-Woo Choi Kwang W Oh Arum Han	2001	Biomedical Microdevices2001，3，：	1
	2	Multilayer plastic/glass microfluidic systems containing electrical and mechanical functionality 显示文摘	Han Arum Wang Olivia Graft Mason	2003	Lab on a Chip2003，3，：	1
	3	Microfluidic systems for axonal growth and regeneration research显示文摘Damage to the adult mammalian central nervous system(CNS)often results in persistent neurological deficits with limited recovery of functions.The past decade has seen increasing research efforts in neural regeneration research with the ultimate goal of achieving functional recovery.Many studies have focused on prevention of further neural damage and restoration of functional connections that are com-	Sunja Kim Jaewon Park Arum Han Jianrong Li	2014	Neural Regeneration Research2014，9，19：	0
	4	Development of single-cell-level microfluidic tech no logy for long-term growth visualization of living cultures of Mycobacterium smegmatis显示文摘Analysis of growth and death kinetics at single-cell resolution is a key step in understanding the complexity of the nonreplicating growth phenotype of the bacterial pathogen Mycobacterium tuberculosis.Here,we developed a single-cell-resolution microfluidic mycobacterial culture device that allows time-lapse microscopy-based Iong-term phenotypic visualization of the live replication dynamics of mycobacteria.This technology was successfully applied to monitor the real-time growth dynamics of the fast-growing model strain Mycobacterium smegmatis(M.smegmatis)while subjected to drug treatment regimens during continuous culture for 48 h inside the microfluidic device.A clear morphological change leading to significant swelling at the poles of the bacterial membrane was observed during drug treatment.In addition,a small subpopulation of cells surviving treatment by frontline antibiotics was observed to recover and achieve robust replicative growth once regular culture media was provided,suggesting the possibility of identifying and isolating nonreplicative mycobacteria.This device is a simple,easy-to-use,and low-cost solution for studying the single-cell phenotype and growth dynamics of mycobacteria,especially during drug treatment.	Han Wang Gloria M.Conover Song-I Han James C.Sacchettini Arum Han	2021	Microsystems & Nanoengineering2021，7，3：	0

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