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| 1 | Systematic mechanism-orientated approach to chronic pancreatitis pain显示文摘Pain in chronic pancreatitis(CP) shows similarities with other visceral pain syndromes(i.e.,inflammatory bowel disease and esophagitis),which should thus be managed in a similar fashion.Typical causes of CP pain include increased intrapancreatic pressure,pancreatic inflammation and pancreatic/extrapancreatic complications.Unfortunately,CP pain continues to be a major clinical challenge.It is recognized that ongoing pain may induce altered central pain processing,e.g.,central sensitization or pro-nociceptive pain modulation.When this is present conventional pain treatment targeting the nociceptive focus,e.g.,opioid analgesia or surgical/endoscopic intervention,often fails even if technically successful.If central nervous system pain processing is altered,specific treatment targeting these changes should be instituted(e.g.,gabapentinoids,ketamine or tricyclic antidepressants).Suitable tools are now available to make altered central processing visible,including quantitative sensory testing,electroencephalograpy and(functional) magnetic resonance imaging.These techniques are potentially clinically useful diagnostic tools to analyze central pain processing and thus define optimum management approaches for pain in CP and other visceral pain syndromes.The present review proposes a systematic mechanism-orientated approach to pain management in CP based on a holistic view of the mechanisms involved.Future research should address the circumstances under which central nervous system pain processing changes in CP,and how this is influenced by ongoing nociceptive input and therapies.Thus we hope to predict which patients are at risk for developing chronic pain or not responding to therapy,leading to improved treatment of chronic pain in CP and other visceral pain disorders. | Stefan AW Bouwense Marjan de Vries Luuk TW Schreuder Soren S Olesen Jens B Frokjær Asbjorn M Drewes Harry van Goor Oliver HG Wilder-Smith | 2015 | World Journal of Gastroenterology2015，21，1： | 6 |
| 2 | Assessment of the cardiovascular and gastrointestinal autonomic complications of diabetes显示文摘The global prevalence of diabetes mellitus is increasing; arguably as a consequence of changes in diet, lifestyle and the trend towards urbanization. Unsurprisingly, the incidence of both micro and macrovascular complications of diabetes mirrors this increasing prevalence. Amongst the complications with the highest symptom burden, yet frequently under-diagnosed and sub-optimally treated, is diabetic autonomic neuropathy, itself potentially resulting in cardiovascular autonomic neuropathy and gastrointestinal(GI) tract dysmotility. The aims of this review are fourfold. Firstly to provide an overview of the pathophysiological processes that cause diabetic autonomic neuropathy. Secondly, to discuss both the established and emerging cardiometric methods for evaluating autonomic nervous system function in vivo. Thirdly, to examine the tools for assessing pan-GI and segmental motility and finally, we will provide the reader with a summary of putative non-invasive biomarkers that provide a pathophysiological link between lowgrade neuro inflammation and diabetes, which may allow earlier diagnosis and intervention, which in future may improve patient outcomes. | Christina Brock Birgitte Brock Anne Grave Pedersen Asbjorn Mohr Drewes Niels Jessen Adam D Farmer | 2016 | World Journal of Diabetes2016，7，16： | 5 |
| 3 | On modelling the interplay between microporosity formation and hot tearing in aluminium direct-chill casting 显示文摘 | Mohammed M'Hamadi Asbjorn Mo | 2005 | Materials Science and Engineering2005，，： | 1 |
| 4 | An integrated wastewater treatment system for land-based fish-farming显示文摘 | IVAR O KANG L ASBJORN B | 2000 | Aquacultural engineering2000，22，： | 1 |
| 5 | Liquidus temperatures for primary crystallization of cryolitein molten salt systems of interest for aluminum electrolysis 显示文摘 | Asbjorn Solheim Sverre Rolseth Egil Skybakmoen Lisbet Stoen Astound Sterten Trond Store | 1996 | Metallurgical and Materials Transactions B1996，27，： | 1 |
| 6 | Burden sharing and fairness principles in international climate policy显示文摘 | Lasse R Asbjorn T Arild U | 2002 | International Environmental Agreements:Politics Law and Economics2002，2，1： | 1 |
| 7 | Clinical trial of gingival retraction cords显示文摘 | Asbjorn Jokstad | 1999 | J Prosthet Dent1999，81，： | 1 |
| 8 | Strain rate imaging in normal and reduced diastolic function:comparison with pulsed Doppler tissue imaging of the mitral annulus显示文摘 | Asbjorn S Slordahl S Andreas H | 2001 | J Am Soc Echocardiography2001，14，3： | 1 |
| 9 | The political economy of technology support: making decisions about carbon capture and storage and low carbon energy technologies显示文摘 | Asbjorn Torvanger | 2011 | Global Environmental Change2011，，21： | 1 |
| 10 | Strain rate imaging in normal and reduced diastolic function: comparison with pulsed Doppler tissue imaging of the mitral annulus显示文摘 | Asbjorn S Slordahl S Andreas H | 2001 | J Am Soc Echocardiogr2001，14，3： | 1 |
| 11 | Biofuel, the environment, and food security: A global problem explored through a case study of Indonesia 显示文摘 | NICOLA COLBRAN & ASBJORN EIDE | 2008 | Sustainable Development Law & Policy2008，，9： | 1 |
| 12 | Water quality and partial mass budget in extensive shrimp ponds in Bangladesh 显示文摘 | ADDUL W M ASBJORN B | 2003 | Aquaculture2003，218，： | 1 |
| 13 | Air pollution policies in Europe:efficiency gains from integrating climate effects with damage costs to health and crops显示文摘 | PetterTollefsen KristinRypdal Asbjorn Torvanger | | 0，，12： | 1 |
| 14 | Solids management and removal for intensive land-based aquaculture production systems 显示文摘 | SIMON J C ASBJORN B | 2000 | Aquacullural Engineering2000，22，： | 1 |
| 15 | Combining the role of convenience and consideration set size inexplaining fish consumption in Norway显示文摘 | Asbjorn Warvik Rortveit Svein Ottar Olsen | 2009 | Appetite2009，52，2： | 1 |
| 16 | Health and environmental benefits from air pollution reductions in Hungary 显示文摘 | AUNAN K PATZAY G ASBJORN AAHEIM H | 1998 | Sci Total Environ1998，212，23： | 1 |
| 17 | No evidence supports differences in clinical perfbrmance of ceramic inlays and other posterior restorations 显示文摘 | Asbjorn J | 2003 | Evidence- Based Dentistry2003，4，2： | 1 |
| 18 | Kinetics and stoichiometry of sulfide oxida-tion by sewer biofilms显示文摘 | Asbjorn Haaning Nielsen Thorkild Hvitved-Jacobs-en Jes Vollertsen | | 0，，： | 1 |
| 19 | Solids management and removal for intensive land-based aquaculture production systems显示文摘 | Simon J Cripps Asbjorn Bergheim | 2000 | Aquacult Eng2000，22，1： | 1 |
| 20 | Coupled current distribution and convection simulator for electrolysis cells显示文摘 | Stein K B Johansen T Asbjorn S | 2001 | Light Metals2001，，： | 1 |
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