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2篇 您的检索式:作者名="Assunta Marrocchi"
    题名 作者 年代 出处 被引量
1Ecotoxicology and Environmental Safety 显示文摘Paola Gramatica Ester Papa Assunta Marrocchi Lucio Minuti Aldo Taticchi 200766:1252007,66,:1
2Waste-minimized C(sp^(3))-H activation for the preparation of fused N-heterocycles显示文摘By exploiting the combined use of a heterogeneous recyclable palladium(II)-bis(N-heterocyclic carbene)catalyst and cyclopentyl methyl ether(CPME)as a convenient recoverable safer reaction medium,an effective wasteminimized approach has been developed for the intramolecular Pd-catalyzed C(sp3)-H activation of methyl pyrrole derivatives.This synthetic tools has allowed to access condensed N-heterocycles generally endowed with biological activities and representatively are the core motif of complex molecules such as Mitomycines and Tylophorines.The heterogeneous catalytic system could be recovered and reused up to representative five runs without any loss in efficiency.The target products(19 examples)have been obtained selectively and with excellent isolated yields up to 93%.The approach leads to the definition of a protocol with a very good E-factor(21)which is much lower(up to 98%)than those of comparable literature examples.Other green metrics have been calculated and the data collected demonstrate that our newly developed protocol is very promising in terms of its environmental impact profile.Nihad Salameh Francesco Minio Gabriele Rossini Assunta Marrocchi Luigi Vaccaro 2023Green Synthesis and Catalysis2023,4,3:0
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