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| 1 | Diffusion-weighted MR imaging of normal and abnorma scrotum: preliminary results显示文摘阴囊的磁性的回声(先生) 成像在阴囊的疾病的评估代表一个重要补加的诊断工具。散开加权(DW ) 先生成像是一种发展中的技术,证明了改进织物描述。我们在阴囊的损害的察觉和描述评估了可行性和 DW 先生成像的诊断性能。我们回顾地在 26 个人评估了 31 阴囊的损害(23 intratesticular 和 8 extratesticular ) 。所有先生考试在一个 1.5-T 单位上被执行,用骨盆阶段的数组卷。DW 序列用单个射击被获得, multislice 旋转回响平面散开脉搏顺序和 0 和 900 的一个 b 因素; s 公里 −2 。DW 先生特征和明显的散开系数(模数转换器) 正常阴囊的内容和阴囊的疾病珍视被评估。在正常阴囊,良性的损害和阴囊的恶意的 ADC 价值之间的比较被执行。常规序列,独自一个的 DW 图象和 DW 成像的精确性在区分与常规图象结合了从恶意的阴囊的损害良性被计算。阴囊的恶意的模数转换器价值与正常睾丸和良性的 intratesticular 损害的那些不同,并且 ADC 正常 epididymis 从那些良性的 extratesticular 损害珍视(P< 0.05 ) 。常规成像,独自一个的 DW 成像和在 intratesticular 损害的描述与常规序列相结合的 DW 先生的全面精确性是 91 %, 87 %并且 100 %分别地。我们的调查结果建议 DW 先生成像和模数转换器价值可以在阴囊的疾病的诊断和描述提供珍贵信息。 | Athina C Tsili Maria I Argyropoulou Dimitrios Giannakis Stavros Tsampalas Nikolaos Sofikitis Konstantinos Tsampoulas | 2012 | Asian Journal of Andrology2012，14，4： | 18 |
| 2 | Advances of multidetector computed tomography in the characterization and staging of renal cell carcinoma显示文摘Renal cell carcinoma(RCC) accounts for approximately 90%-95% of kidney tumors. With the widespread use of cross-sectional imaging modalities, more than half of RCCs are detected incidentally, often diagnosed at an early stage. This may allow the planning of more conservative treatment strategies. Computed tomography(CT) is considered the examination of choice for thedetection and staging of RCC. Multidetector CT(MDCT) with the improvement of spatial resolution and the ability to obtain multiphase imaging, multiplanar and threedimensional reconstructions in any desired plane brought about further improvement in the evaluation of RCC. Differentiation of RCC from benign renal tumors based on MDCT features is improved. Tumor enhancement characteristics on MDCT have been found closely to correlate with the histologic subtype of RCC, the nuclear grade and the cytogenetic characteristics of clear cell RCC. Important information, including tumor size, localization, and organ involvement, presence and extent of venous thrombus, possible invasion of adjacent organs or lymph nodes, and presence of distant metastases are provided by MDCT examination. The preoperative evaluation of patients with RCC was improved by depicting the presence or absence of renal pseudocapsule and by assessing the possible neoplastic infiltration of the perirenal fat tissue and/or renal sinus fat compartment. | Athina C Tsili Maria I Argyropoulou | 2015 | World Journal of Radiology2015，7，6： | 16 |
| 3 | Apparent diffusion coefficient values of normal testis and variations with age显示文摘在阴囊的病理的评估的散开加权的磁性的回声成像(DWI ) 的实用性最近被报导了。当解释正常阴囊的解剖和病理时,阴囊的明显的散开系数(模数转换器) 珍视的正常和他们有年龄的变化的一本标准参考书是必要的。我们用 DWI 评估了 147 个正常睾丸,包括从 20-39 年(组 1 ) 的 53 个人的 71 个睾丸,从 40-69 年(组 2 ) 的 42 个人的 67 个睾丸和从比 70 年(组 3 ) 老的六个人的九个睾丸。DWI 沿着轴的飞机被执行,用单个射击, multislice 纺纱回响平面散开脉搏顺序和 0 和 900 s 公里 −2 的 b 值。正常阴囊的实质的模数转换器价值的平均数和标准差独立为每个年龄组被计算。柱子 hoc 分析(Dunnett T3 ) 跟随的变化(ANOVA ) 的分析被用于统计目的。模数转换器价值(×正常阴囊的织物的 10 −3 公里 2 s −1) 在年龄组之中是不同的(组 1:1.08 ±0.13;组 2:1.15 ±0.15 和组 3:1.31 ±0.22 ) 。ANOVA 在年龄组之中在吝啬的模数转换器揭示了差别(F = 11.391, P <0.001 ) 。波斯特 hoc 分析显示出组之间的差别 1 和 2 (P = 0.008 ) 并且在组之间 1 和 3 (P = 0.043 ) ,然而并非在组之间 2 和 3 (P = 0.197 ) 。我们的调查结果建议正常阴囊的织物的模数转换器价值与推进年龄增加。 | Athina C Tsili Dimitrios Giannakis Anastasios Sylakos Alexandra Ntorkou Loukas G Astrakas Nikolaos Sofikitis Maria I Argyropoulou | 2014 | Asian Journal of Andrology2014，16，3： | 8 |
| 4 | Albuminuria as a marker of arterial stiffness in chronic kidney disease patients显示文摘AIM:To access the association between albuminuria levels and arterial stiffness in non-diabetic patients with hypertension and chronic kidney disease(CKD) stages 1-2,treated with renin angiotensin blockade agents plus other hypertensive drugs when needed.METHODS:One hundred fifteen patients [median age 52 years(68% males)] were consequently enrolled in the study.For each patient,we recorded gender,age,body mass index(BMI),peripheral systolic blood pressure(p SBP),peripheral diastolic blood pressure,peripheral pulse pressure,central systolic blood pressure(c SBP),central diastolic blood pressure(c DBP),central pulse pressure(c PP),hematocrit,hemoglobin,hs CRP,total cholesterol triglycerides,high-density lipoprotein-C,low-density lipoprotein-C,calcium,phosphorus,parathormone,and albumin,as well as 24 h urine albumin excretion.According to 24-h urine albumin collection,patients were then classified as those with moderately increased albuminuria(formerly called macroalbuminuria)(≤ 300 mg/d) and those with severely increased albuminuria(formerly called macroaluminuria(> 300 mg/d).We considered aortic stiffness(AS) indices [carotid femoral pulse wave velocity(PWVc-f) and augmentation index(AIx)] as primary outcomes ofthe study.We explored potential correlations between severely increased albuminuria and AS indices using a multiple linear regression model.RESULTS:Fifty-eight patients were included in the moderately increased albuminuria group and 57 in the severely increased albuminuria.Blood pressure measurements of the study population were 138 ± 14/82 ± 1.3 mm Hg(systolic/diastolic).There were no significant differences in age,sex,and BP measurements between the two groups.Patients with severely increased albuminuria had higher PWV and AIx than patients with moderately increased albuminuria(P < 0.02,P < 0.004,respectively).In addition these patients exhibited higher BMI(P < 0.03),hs CRP(P < 0.001),and fibrinogen levels(P < 0.02) compared to patients with moderately increased albuminuria.In multivariate linear regression analysis,severely increased albuminuria(β = 1.038,P < 0.010) p SBP(β = 0.028,P < 0.034) and Ht(β = 0.171,P = 0.001) remained independent determinants of the increased PWVc-f.Similarly,severely increased albuminuria(β = 4.385,P < 0.012),c SBP(β = 0.242,P < 0.001),c PP(β = 0.147,P < 0.01) and Ht levels(β = 0.591,P < 0.013) remained independent determinants of increased AIx.CONCLUSION:These findings demonstrate an independent association between AS indices and severely increased albuminuria in non-diabetic,hypertensive patients with CKD stages 1-2 treated with renin angiotensin aldosterone system blockers. | Rigas G Kalaitzidis Despina P Karasavvidou Athina Tatsioni Kosmas Pappas Giorgos Katatsis Angelos Liontos Moses S Elisaf | 2015 | World Journal of Nephrology2015，4，3： | 5 |
| 5 | Potential role of imaging in assessing harmful effects on spermatogenesis in adult testes with varicocele显示文摘Varicocele is characterized by an abnormal dilatation and retrograde blood flow in the spermatic veins. Varicocele is the leading correctable cause of male infertility. Although it is highly prevalent in infertile men, it is also observed in individuals with normal fertility. Determining which men are negatively affected by varicocele would enable clinicians to better select those men who will benefit from treatment. To assess the functional status of the testes in men with varicocele, color Doppler sonographic parameters were evaluated. Testicular arterial blood flow was significantly reduced in men with varicocele, reflecting an impairment of spermatogenesis. An improvement in the testicular blood supply was found after varicocelectomy on spectral Doppler analysis. Testicular contrast harmonic imaging and elastography might improve our knowledge about the influence of varicocele on intratesticular microcirculation and tissue stiffness, respectively, providing possible information on the early damage of testicular structure by varicocele. Magnetic resonance imaging(MRI), with measurement of apparent diffusion coefficient has been used to assess the degree of testicular dysfunction and to evaluate the effectiveness of varicocele repair. Large prospective studies are needed to validate the possible role of functional sonography and MRI in the assessment of early defects of spermatogenesis in testes with varicocele. | Athina C Tsili Olga N Xiropotamou Anastasios Sylakos Vasilios Maliakas Nikolaos Sofikitis Maria I Argyropoulou | 2017 | World Journal of Radiology2017，9，2： | 4 |
| 6 | Metalloproteinase expression after desflurane preconditioning in hepatectomies:A randomized clinical trial显示文摘BACKGROUND Hepatectomy with inflow occlusion results in ischemia-reperfusion injury;however,pharmacological preconditioning can prevent such injury and optimize the postoperative recovery of hepatectomized patients.The normal inflammatory response after a hepatectomy involves increased expression of metalloproteinases,which may signal pathologic hepatic tissue reformation.AIM To investigate the effect of desflurane preconditioning on these inflammatory indices in patients with inflow occlusion undergoing hepatectomy.METHODS This is a single-center,prospective,randomized controlled trial conducted at the 4th Department of Surgery of the Medical School of Aristotle University of Thessaloniki,between August 2016 and December 2017.Forty-six patients were randomized to either the desflurane treatment group for pharmacological preconditioning(by replacement of propofol with desflurane,administered 30 min before induction of ischemia)or the control group for standard intravenous propofol.The primary endpoint of expression levels of matrix metalloproteinases and their inhibitors was determined preoperatively and at 30 min posthepatic reperfusion.The secondary endpoints of neutrophil infiltration,coagulation profile,activity of antithrombin III(AT III),protein C(PC),protein S and biochemical markers of liver function were determined for 5 d postoperatively and compared between the groups.RESULTS The desflurane treatment group showed significantly increased levels of tissue inhibitor of metalloproteinases 1 and 2,significantly decreased levels of matrix metalloproteinases 2 and 9,decreased neutrophil infiltration,and less profound changes in the coagulation profile.During the 5-d postoperative period,all patients showed significantly decreased activity of AT III,PC and protein S(vs baseline values,P<0.05).The activity of AT III and PC differed significantly between the two groups from postoperative day 1 to postoperative day 5(P<0.05),showing a moderate drop in activity of AT III and PC in the desflurane treatment group and a dramatic drop in the control group.Compared to the control group,the desflurane treatment group also had significantly lower international normalized ratio values on all postoperative days(P<0.005)and lower serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase values on postoperative days 2 and 3(P<0.05).Total length of stay was significantly less in the desflurane group(P=0.009).CONCLUSION Desflurane preconditioning can lessen the inflammatory response related to ischemia-reperfusion injury and may shorten length of hospitalization. | Eleni Koraki Ioannis Mantzoros Christos Chatzakis Anna Gkiouliava Angeliki Cheva Athina Lavrentieva Freideriki Sifaki Helena Argiriadou Isaak Kesisoglou Konstantinos Galanos-Demiris Stefanos Bitsianis Konstantinos Tsalis | 2020 | World Journal of Hepatology2020，12，11： | 4 |
| 7 | Transient micro-elastography:A novel non-invasive approach to measure liver stiffness in mice显示文摘AIM:To develop and validate a transient micro-elastography device to measure liver stiffness(LS) in mice.METHODS:A novel transient micro-elastography(TME) device,dedicated to LS measurements in mice with a range of measurement from 1-170 kPa,was developed using an optimized vibration frequency of 300 Hz and a 2 mm piston.The novel probe was validated in a classical fibrosis model(CCl4) and in a transgenic murine model of systemic amyloidosis.RESULTS:TME could be successfully performed in control mice below the xiphoid cartilage,with a mean LS of 4.4 ± 1.3 kPa,a mean success rate of 88%,and an excellent intra-observer agreement(0.98).Treatment with CCl4 over seven weeks drastically increased LS as compared to controls(18.2 ± 3.7 kPa vs 3.6 ± 1.2 kPa).Moreover,fibrosis stage was highly correlated with LS(Spearman coefficient = 0.88,P < 0.01).In the amyloidosis model,much higher LS values were obtained,reaching maximum values of > 150 kPa.LS significantly correlated with the amyloidosis index(0.93,P < 0.0001) and the plasma concentration of mutant hapoA-□(0.62,P < 0.005).CONCLUSION:Here,we have established the first non-invasive approach to measure LS in mice,and have successfully validated it in two murine models of high LS. | Cécile Bastard Matteo R Bosisio Michèle Chabert Athina D Kalopissis Meriem Mahrouf-Yorgov Hélène Gilgenkrantz Sebastian Mueller Laurent Sandrin | 2011 | World Journal of Gastroenterology2011，17，8： | 4 |
| 8 | Detecting community structure using label propagation with consensus weight in complex network显示文摘Community detection is a fundamental work to analyse the structural and functional properties of complex networks.The label propagation algorithm(LPA) is a near linear time algorithm to find a good community structure. Despite various ubsequent advances, an important issue of this algorithm has not yet been properly addressed. Random update orders within the algorithm severely hamper the stability of the identified community structure. In this paper, we executed the asic label propagation algorithm on networks multiple times, to obtain a set of consensus partitions. Based on these onsensus partitions, we created a consensus weighted graph. In this consensus weighted graph, the weight value of the dge was the proportion value that the number of node pairs allocated in the same cluster was divided by the total number f partitions. Then, we introduced consensus weight to indicate the direction of label propagation. In label update steps,y computing the mixing value of consensus weight and label frequency, a node adopted the label which has the maximum mixing value instead of the most frequent one. For extending to different networks, we introduced a proportion parameter o adjust the proportion of consensus weight and label frequency in computing mixing value. Finally, we proposed an pproach named the label propagation algorithm with consensus weight(LPAcw), and the experimental results showed that he LPAcw could enhance considerably both the stability and the accuracy of community partitions. | 梁宗文 李建平 杨帆 Athina Petropulu | 2014 | Chinese Physics B2014，23，9： | 3 |
| 9 | Resources and capabilities as drivers of hotel environmental marketing strategy: Implications for competitive advantage and performance显示文摘 | Leonidas C. Leonidou Constantinos N. Leonidou Thomas A. Fotiadis Athina Zeriti | 2013 | Tourism Management2013，，： | 2 |
| 10 | Molecular characterization of circulating tumor cells in breast cancer: challenges and promises for individualized cancer treatment显示文摘 | Evi S. Lianidou Athina Markou Areti Strati | 2012 | Cancer and Metastasis Reviews2012，，3： | 2 |
| 11 | Helicobacter pylori infection as an environmental risk factor for migraine without aura显示文摘 | Konstantina G. Yiannopoulou Athina Efthymiou Kleanthis Karydakis Andreas Arhimandritis Nikolaos Bovaretos Mihalis Tzivras | 2007 | The Journal of Headache and Pain2007，，6： | 2 |
| 12 | Ectopic expression of clusterin/apolipoprotein J or Bcl-2 decreases the sensitivity of HaCaT cells to toxic effects of ropivacaine显示文摘Local anesthetics inhibit cell proliferation and induce apoptosis in various cell types. Ropivacaine, a unique, novel tertiary amine-type anesthetic, was shown to inhibit the proliferation of several cell types including keratinocytes. We found that Ropivacaine could inhibit the proliferation and induce apoptosis in an immortalized human keratinocyte line, HaCaT, in a dose- and time-dependent manner and with the deprivation of serum. The dose-dependent induction of apoptosis by ropivacaine was demonstrated by DNA fragmentation analysis and the proteolytic cleavage of a caspase-3 substrate — poly (ADP-ribose) polymerase (PARP). In addition, ropivacaine downregulated the expression of clusterin/ apoliporotein J, a protein with anti-apoptotic properties, in a dose-dependent manner, which well correlated with the induction of apoptosis of HaCaT cells. To investigate the role of clusterin/apoliporotein J in ropivacaine-induced apoptosis, HaCaT cells overexpressing clusterin/apoliporotein J were generated and compared to cells expressing the well estab- lished anti-apoptotic Bcl-2 protein. Ectopic overexpression of the secreted form of clusterin/apoliporotein J or Bcl-2 decreased the sensitivity of HaCaT cells to toxic effects of ropivacaine as demonstrated by DNA fragmentation, the proteolytic cleavage of PARP and by a reduction in procaspase-3 expression. Furthermore, the downregulation of endogenous clusterin/apolipoprotein J levels by ropivacaine suggested that this might be one mechanism by which ropivacaine induced cell death in HaCaT cells. In conclusion, the ability of ropivacaine to induce antiproliferative responses and to suppress the expression of the anti-apoptotic protein clusterin/apolipoprotein J, combined with previ- ously reported anti-inflammatory activity and analgesic property of the drug, suggests that ropivacaine may have poten- tial utility in the local treatment of tumors. | Evangelos KONTARGIRIS Evangelos KOLETTAS Athina VADALOUCA Ioannis P. TROUGAKOS Efstathios S. GONOS Vasiliki KALFAKAKOU | 2004 | Cell Research2004，14，5： | 2 |
| 13 | Protective effect of amifostine during fractionated radiotherapy in patients with pelvic carcinomas: Results of a randomized trial显示文摘 | Helen Athanassiou Dosia Antonadou Nikos Coliarakis Athina Kouveli Maria Synodinou Michalakis Paraskevaidis George Sarris Gregory R Georgakopoulos Katerina Panousaki Pantelis Karageorgis Nicolas Throuvalas | 2003 | International Journal of Radiation Oncology, Biology, Physics2003，，4： | 2 |
| 14 | Association of breastfeeding with tidal breathing analysis in infants with bronchiolitis显示文摘BACKGROUND Tidal breathing flow-volume(TBFV)analysis provides important information about lung mechanics in infants.AIM To assess the effects of breastfeeding on the TBFV measurements of infants who recover from acute bronchiolitis.METHODS In this cross-sectional study,TBFV analysis was performed in infants with bronchiolitis prior to hospital discharge.The ratio of time to peak expiratory flow to total expiratory time(tPEF/tE)at baseline and after the administration of 400 mcg salbutamol was evaluated.RESULTS A total of 56 infants(35 boys),aged 7.4±2.8 mo,were included.Of them,12.5%were exposed to tobacco smoke and 41.1%were breastfed less than 2 mo.There were no differences in baseline TBFV measurements between the breastfeeding groups;however,those who breastfed longer than 2 mo had a greater change in tPEF/tE after bronchodilation(12%±10.4%vs 0.9%±7.1%;P<0.001).Moreover,there was a clear dose-response relationship between tPEF/tE reversibility and duration of breastfeeding(P<0.001).In multivariate regression analysis,infants who breastfed less(regression coefficient-0.335,P=0.010)or were exposed to cigarette smoke(regression coefficient 0.353,P=0.007)showed a greater change in tPEF/tE after bronchodilation,independent of sex,prematurity,and family history of asthma or atopy.CONCLUSION Infants who recover from bronchiolitis and have a shorter duration of breastfeeding or are exposed to cigarette smoke,have TBFV measurements indicative of obstructive lung disease. | Evanthia Perikleous Sotirios Fouzas Athina Karageorgiou Paschalis Steiropoulos Evangelia Nena Athanasios Chatzimichael Aggelos Tsalkidis Emmanouil Paraskakis | 2021 | World Journal of Clinical Pediatrics2021，10，6： | 2 |
| 15 | Intravitreal Adalimumab for Refractory Uveitis-Related Macular Edema显示文摘 | Sofia Androudi Evangelia Tsironi Christos Kalogeropoulos Athina Theodoridou Periklis Brazitikos | 2010 | Ophthalmology2010，，8： | 1 |
| 16 | Matrix completion in collocated MIMO radar: recoverability, bounds & theoretical guarantees显示文摘 | Dionysios S K and Athina P P | 2014 | IEEE Transactions on Signal Processing2014，62，2： | 1 |
| 17 | Spectroscopic studies on the interaction between erlotinib hydrochloride and bovine serum albumin 显示文摘 | ATHINA P REBECCA JG RICHARD AF | 2005 | J Agric Food Chem2005，53，1： | 1 |
| 18 | Serum soluble urokinase plasminogen activator receptor as a screening test for the early diagnosis of hepatocellular carcinoma显示文摘 | Athina Chounta Christofer Ellinas Vassiliki Tzanetakou Fani Pliarhopoulou Virginia Mplani Angelos Oikonomou Kostantinos Leventogiannis Evangelos J. Giamarellos‐Bourboulis | 2015 | Liver Int2015，，2： | 1 |
| 19 | Proximal Tubular Epithelial Cell Integrins Respond to High Glucose by Altered Cell-Matrix Interactions and Differentially Regulate Matrixin Expression显示文摘 | Panagiotis M Karamessinis Athina K | 2002 | Laboratory Investigation2002，82，： | 1 |
| 20 | Proximal tubular epithelial cell integrins respond to high glucose by ahered cell matrix interactions and differentially regulate matrixin expression 显示文摘 | Panagiotis M Karamessinis PM Athina K | 2002 | Laboratory Investigation2002，82，8： | 1 |
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