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| 1 | Impact of machine perfusion of the liver on post-transplant biliary complications: A systematic review显示文摘AIM To review the clinical impact of machine perfusion(MP) of the liver on biliary complications post-transplantation, particularly ischaemic-type biliary lesions(ITBL). METHODS This systematic review was performed in accordance with the Preferred Reporting Systematic Reviews and MetaAnalysis(PRISMA) protocol. The following databases were searched: PubMed, MEDLINE and Scopus. The keyword 'liver transplantation' was used in combination with the free term 'machine perfusion'. Clinical studies reporting results of transplantation of donor human livers following ex situ or in situ MP were analysed. Details relating to donor characteristics, recipients, technique of MP performed and post-operative biliary complications(ITBL, bile leak and anastomotic strictures) were critically analysed.RESULTS Fifteen articles were considered to fit the criteria for this review. Ex situ normothermic MP was used in 6 studies, ex situ hypothermic MP in 5 studies and the other 4 studies investigated in situ normothermic regional perfusion(NRP) and controlled oxygenated rewarming. MP techniques which have per se the potential to alleviate ischaemia-reperfusion injury: Such as hypothermic MP and NRP, have also reported lower rates of ITBL. Other biliary complications, such as biliary leak and anastomotic biliary strictures, are reported with similar incidences with all MP techniques. There is currently less clinical evidence available to support normothermic MP as a mitigator of biliary complications following liver transplantation. On the other hand, restoration of organ to full metabolism during normothermic MP allows assessment of hepatobiliary function before transplantation, although universally accepted criteria have yet to be validated.CONCLUSION MP of the liver has the potential to have a positive impact on post-transplant biliary complications, specifically ITBL, and expand extended criteria donor livers utilisation. | Yuri L Boteon Amanda PCS Boteon Joseph Attard Lorraine Wallace Ricky H Bhogal Simon C Afford | 2018 | World Journal of Transplantation2018，8，6： | 2 |
| 2 | 查看详情显示文摘 | Attard G S Glyde C Goltner C G | | 0，，： | 1 |
| 3 | Phase I trialinvolving the pharmacodynamic ( PD) study of circulatingtumour cells, of CP - 7 5 1 8 7 1 , a monoclonal antibody againstthe insulin - like growth factor 1 receptor ( IGF -1R ),with docetaxel ( D) in patients with advanced cancer显示文摘 | ATTARD G FONG P C MOLIFE R | | JC lin Oncol0，22，9： | 1 |
| 4 | Liquid-crystalline phases as templated for the synthesis of mesoporous silica显示文摘 | Attard G S Glyde J C G61tner C G | 1995 | Nature1995，378，： | 1 |
| 5 | Liquid-crystalline phases as templates for the synthesis of mesoporous silica显示文摘 | Attard G S Glyde J C G ltner C G | 1995 | Nature1995，378，： | 1 |
| 6 | Liquid - crystalline phases as templates for the synthesis of mesoporous 显示文摘 | ATTARD G S GLYDE J C GOLTNER C G | 1995 | Nature1995，378，： | 1 |
| 7 | Liquid crystal templates for nanostructured metals显示文摘 | ATTARD G S GLYDE J C GOLTNER C G | 1997 | Angew Chem Int Ed Engl1997，36，： | 1 |
| 8 | Develop- mental hemostasis: age-specific differences in the levels of hemostatic proteins 显示文摘 | Attard C van der Straaten T Karlaftis V | 2013 | J Thromb Haemost2013，11，10： | 1 |
| 9 | 显示文摘 | Attard G S Glyde J C Goltner C G | 1995 | Nature1995，378，： | 1 |
| 10 | Prostate cancer显示文摘 | Attard G Parker C Eeles R A | 2015 | Lancet2015，387，10013： | 1 |
| 11 | Developmental haemostasis : age-specific differences in the quantity of haemostatie proteins显示文摘 | Attard C Karlaftis V Igujatovic V et O1 | 2013 | J Thromb Haemost2013，11，10： | 1 |
| 12 | Tunable gold catalysts for selective hydrocarbon oxidation under mild conditions 显示文摘 | Hughes M D Xu Y J Jenkins P Mcmorn P Landon P Enache D I Carley A F Attard G A Hutchings G J King F Stitt E H Johnston P Griffin K Kiely C J | 2005 | Nature2005，437，7062： | 1 |
| 13 | Age influences TSH serum levels after withdrawal of 1-thyroxlne or rhTSH stimulation in patients affected by differentiated thyroid cancer 显示文摘 | Montesano T Durante C Attard M | 2007 | Biomed Pharmacother2007，61，8： | 1 |
| 14 | Long-term surveil- lance of papillary thyroid cancer patients who do not undergo postoperative radioiodine remnant ablation: is there a role for serum thyroglobulin measurement? 显示文摘 | Durantc C Montcsano T Attard M | 2012 | J ClinEndocrinol Metab2012，97，8： | 1 |
| 15 | M, Specimen size and shape effect in split Hopkinson pressure bar testing 显示文摘 | Pankow M Attard C Waas A | 2009 | The Journal of Strain analysis for Engineering Design2009，，： | 1 |
| 16 | Identification and optimal postsurgical follow-up of patients with very low-risk papillary thyroid microcarcinomas显示文摘 | Durante C Attard M Torlontano M | 2010 | J Clin Endocrinol Metab2010，95，11： | 1 |
| 17 | Developmental hemostasis:age-specific differences in the levels of hemostatic proteins显示文摘 | Attard C van der Straaten T Karlaftis V | 2013 | J Thromb Haemost2013，11，10： | 1 |
| 18 | Tunable gold catalysts for selective hydrocarbon oxidation under mild conditions 显示文摘 | HUGHES M D XU Y J JENKINS P MCMORN P LANDON P ENACHE D I CARLEY A F ATTARD G A HUTCHINGS G J KING F STITT E H JOHNSTON P GRIFFIN K KIELY C J | 2005 | Nature2005，437，7062： | 1 |
| 19 | Shifts between Nitrospira- and Nitrobacter-like nitrite oxidizers underlie the response of soil potential nitrite oxidation to changes in tillage practices显示文摘 | Attard E Poly F Commeaux C etal | 2010 | Environmental Microbiology2010，12，2： | 1 |
| 20 | Liquid-crystalline phasesas templates for the synthesis of mesoporous silica显示文摘 | Attard G S Glyde J C Gltner C G | 1995 | Nature1995，378，： | 1 |
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