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| 1 | Enteral nutrition in acute pancreatitis:A review of the current evidence显示文摘The use of enteral feeding as part of the management of acute pancreatitis dates back almost two decades.This review describes the indications for and limitations of enteral feeding for the treatment of acute pancreatitis using up-to-date evidence-based data.A systematic review was carried out to analyse current data on the use of enteral nutrition in the management of acute pancreatitis.Relevant literature was analysed from the viewpoints of enteral vs parenteral feeding,early vs delayed enteral nutrition,nasogastric vs nasojejunal feeding,and early oral diet and immunonutrition,particularly glutamine and probiotic supplementation.Finally,current applicable guidelines and the effects of these guidelines on clinical practice are discussed.The latest meta-analyses suggest that enteral nutrition significantly reduces the mortality rate of severe acute pancreatitis compared to parenteral feeding.To maintain gut barrier function and prevent early bacterial translocation,enteral feeding should be commenced within the first 24 h of hospital admission.Also,the safety of nasogastric feeding,which eases the administration of enteral nutrients in the clinical setting,is likely equal to nasojejunal feeding.Furthermore,an earlylow-fat oral diet is potentially beneficial in patients with mild pancreatitis.Despite the initial encouraging results,the current evidence does not support the use of immunoenhanced nutrients or probiotics in patients with acute pancreatitis. | Attila Oláh Laszlo Romics Jr | 2014 | World Journal of Gastroenterology2014，20，43： | 81 |
| 2 | Characterization of functional biliary pain and dyspeptic symptoms in patients with sphincter of Oddi dysfunction:Effect of papillotomy显示文摘AIM: To characterize functional biliary pain and other gastrointestinal (GI) symptoms in postcholecystectomy syndrome (PCS) patients with and without sphincter of Oddi dysfunction (SOD) proved by endoscopic sphincter of Oddi manometry (ESOM), and to assess the post- endoscopic sphincterotomy (EST) outcome. METHODS: We prospectively investigated 85 cholecystectomized patients referred for ERCP because of PCS and suspected SOD. On admission, all patients completed our questionnaire. Physical examination, laboratory tests, abdominal ultrasound, quantitative hepatobiliary scintigraphy (QHBS), and ERCP were performed in all patients. Based on clinical and ERCP findings 15 patients had unexpected bile duct stone disease and 15 patients had SOD biliary typeⅠ. ESOM demonstrated an elevated basal pressure in 25 patients with SOD biliary-type Ⅲ. In the remaining 30 cholecystectomized patients without SOD, the liver function tests, ERCP, QHBS and ESOM were all normal. As a control group, 30 ‘asymptomatic’ cholecystectomized volunteers (attended to our hospital for general cardiovascular screening) completed our questionnaire, which is consisted of 50 separate questions on GI symptoms and abdominal pain characteristics. Severity of the abdominal pain (frequency and intensity) was assessed with a visual analogue scale (VAS). In 40 of 80 patients having definite SOD (i.e. patients with SOD biliary typeⅠand those with elevated SO basal pressure on ESOM), an EST was performed just after ERCP. In these patients repeated questionnaires were filled at each follow-up visit (at 3 and 6 mo) and a second lookQHBS was performed 3 mo after the EST to assess the functional response to EST. RESULTS: The analysis of characteristics of the abdominal pain demonstrated that patients with common bile duct stone and definite SOD had a significantly higher score of symptomatic agreement with previously determined biliary-like pain features than patient groups of PCS without SOD and controls. In contrary, no significant differences were found when the pain severity scores were compared in different groups of PCS patients. In patients with definite SOD, EST induced a significant acceleration of the transpapillary bile flow; and based on the comparison of VASs obtained from the pre- and post-EST questionnaires, the severity scores of abdominal pain were significantly improved, however, only 15 of 35 (43%) patients became completely pain free. Post-EST severity of abdominal pain by VASs was significantly higher in patients with predominant dyspepsia at initial presentation as compared to those without dyspeptic symptoms. CONCLUSION: Persistent GI symptoms and general patient dissatisfaction is a rather common finding after EST in patients with SOD, and correlated with the presence of predominant dyspeptic symptoms at the initial presentation, but does not depend on the technical and functional success of EST. | László Madácsy Roland Fejes Gábor Kurucsai Ildikó Joó András Székely Viktória Bertalan Attila Szepes János Lonovics | 2006 | World Journal of Gastroenterology2006，12，42： | 33 |
| 3 | Endoscopic submucosal dissection for premalignant lesions and noninvasive early gastrointestinal cancers显示文摘AIM: To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS: The medical records of 60 consecutive patients (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli University from 2006-2010 were examined. Patients selected for ESDhad premalignant lesions or non-invasive early cancers of the gastrointestinal tract and had endoscopic and histological diagnoses. Early cancers were considered to be confined to the submucosa, with no lymph node involvement by means of computed tomography and endosonography. RESULTS: Sixty ESD procedures were performed. The indications were epithelial lesions (n = 39) (33/39 adenoma with high grade dysplasia, 6/39 adenoma with low grade dysplasia), neuroendocrine tumor (n = 7), cancer (n = 7) (5/7 early colorectal cancer, 2/7 early gastric cancer), granular cell tumor (n = 3), gastrointestinal stromal tumor (n = 2), and leiomyoma (n = 2). En bloc and piecemeal resection rates were 91.6% (55/60) and 8.3% (5/60), respectively. Complete and incomplete resection rates were 96.6% (58/60) and 3.3% (2/60), respectively. Complications were major bleeding [n = 3 (5%)] and perforations [n = 5 (8.3%)] (4 colon, 1 stomach). Two patients with colonic perforations and two patients with submucosal lymphatic and microvasculature invasion (1 gastric carcinoid tumor, 1 colonic adenocarcinoma) were referred to surgery. During a mean follow-up of 12 mo, 1 patient with adenoma with high grade dysplasia underwent a second ESD procedure to resect a local recurrence. CONCLUSION: ESD is a feasible and safe method for treatment of premalignant lesions and early malignant gastrointestinal epithelial and subepithelial lesions. Successful en bloc and complete resection of lesions yield high cure rates with low recurrence. | Sadettin Hulagu Omer Senturk Cem Aygun Orhan Kocaman Altay Celebi Tolga Konduk Deniz Koc Goktug Sirin Ugur Korkmaz Ali Erkan Duman Neslihan Bozkurt Gokhan Dindar Tan Attila Yesim Gurbuz Orhan TarcinDivision of Gastroenterology Derince State Hospital Kocaeli 41900 Turkey Cem Kalayci | 2011 | World Journal of Gastroenterology2011，17，13： | 23 |
| 4 | 丛枝菌根真菌对番茄苗期生长及矿质营养吸收的作用显示文摘以烘干粉碎后的秸秆与灭菌后的土壤配制成栽培基质,接种5种丛枝菌根菌种接种剂进行番茄栽培试验。结果表明,各种丛枝菌根共生微生物接种后对番茄幼苗生长发育和矿质元素吸收有很好的改善和促进作用,特别是对P、K吸收作用显著,对番茄干质量有明显增加作用。通过对番茄菌根侵染情况分析发现根部丛枝菌根侵染率(F)以Glomusmosseae-1和G.mosseae-2最高,可达30%以上,而丛枝菌根形成率(a)则以G.mosseae-2最高,促进番茄生长效果最好的菌种亦为G.mosseae-2。 | 贺超兴 张志斌 王怀松 Tunde Takacs Attila AntonTun | 2006 | 中国蔬菜2006，，1： | 21 |
| 5 | Epithelial-mesenchymal, mesenchymal-epithelial, and endothelial-mesenchymal transitions in malignant tumors: An update显示文摘Epithelial-to-mesenchymal transition(EMT) represents conversion of an epithelial cell in an elongated cell with mesenchymal phenotype, which can occur in physiologic and pathologic processes such as embryogenesis(type 1 EMT), wound healing and/or fibrosis(type 2 EMT) and malignant tumors(type 3 EMT). The proliferation rate, metastasizing and recurrence capacity, as also the individualized response at chemotherapics, in both epithelial and mesenchymal malignant tumors is known to be influenced by reversible switch between EMT and mesenchymal-to-epithelial transition(MET). Although much research work has already been done in these fields, the specific molecular pathways of EMT, relating to the tumor type and tumor localization, are yet to be elucidated. In this paper, based on the literature and personal experience of the authors, an update in the field of EMT vs MET in epithelial and mesenchymal tumors is presented. The authors tried to present the latest data about the particularities of these processes, and also of the so-called endothelialto-mesenchymal transition, based on tumor location. The EMT-angiogenesis link is discussed as a possible valuable parameter for clinical follow-up and targeted therapeutic oncologic management. The paper begins with presentation of the basic aspects of EMT, its classification and assessment possibilities, and concludes with prognostic and therapeutic perspectives. The particularities of EMT and MET in gastric and colorectal carcinomas, pancreatic cancer, hepatocellular and cholangiocarcinomas, and lung, breast and prostate cancers, respectively in sarcomas and gastrointestinal stromal tumors are presented in detail. | Simona Gurzu Sabin Turdean Attila Kovecsi Anca Otilia Contac Ioan Jung | 2015 | World Journal of Clinical Cases2015，3，5： | 20 |
| 6 | Interplay between nitric oxide and VIP in CCK-8-induced phasic contractile activity in the rabbit sphincter of Oddi显示文摘AIM: The sphincter of Oddi (SO) plays an important role in delivery of bile into the duodenum. To establish whether vasoactive intestinal polypeptide (VIP) and nitric oxide (NO) were involved in phasic contractile activity of the rabbit SO stimulated by cholecystokinin-octapeptide (CCK-8).METHODS: Isolated SO muscle rings were cleaned of fat and mounted horizontally on two small L-shaped hooksone of which was connected to a force transducer for the measurement of isometric tension. The experiments were carried out in a thermostatically controlled (37±0.2℃)organ bath (5 mL) containing Krebs solution. The organ fluid was gassed with 95% O2 and 50 mL/L CO2 to keep the pH at 7.40±0.05. Contractile responses to CCK-8 (1μmol/L) were evaluated in the presence and absence of N^G-nitro-L-arginine (LNNA), an inhibitor of NO synthase (100μmol/L), and (p-chloro-D-Phe^6-Leu^17)-VIP (VIPa,30μmol/L), a VIP receptor antagonist.RESULTS: CCK-8 stimulated the phasic activity of the SO.NO synthase inhibition increased the frequency and amplitude of contractions with a slight increase in developed tension.Pre-incubation with VIPa also attenuated this CCK-8 effect.The combined application of LNNA and VIPa abolished the phasic activity of the muscle rings with a marked increase in tension in response to CCK-8.CONCLUSION: VIP and NO together contribute to an increase in phasic activity of SO. | Attila Pálv(o|¨)lgyi Réka Sári József Németh Annamária Szabolcs István Nagy Péter Hegyi János Lonovics Zoltán Szilvássy | 2005 | World Journal of Gastroenterology2005，11，21： | 11 |
| 7 | Selection criteria for preoperative endoscopic retrograde cholangiopancreatography before laparoscopic cholecystectomy and endoscopic treatment of bile duct stones:Results of a retrospective,single center study between 1996-2002显示文摘AIM: The optimal treatment for bile duct stones (in terms of cost, complications and accuracy) is unclear. The aim of our study was to determine the predictive factors for preoperative endoscopic retrograde cholangiopancreatography (ERCP).METHODS: Patients undergoing preoperative ERCP (≤90 d before laparoscopic cholecystectomy) were evaluated in this retrospective study from the 1^st of January 1996 to the 31^st of December 2002. The indications for ERCP were elevated serum bilirubin, elevated liver function tests (LFT), dilated bile duct (≥8 mm) and/or stone at US examination, coexisting acute pancreatitis and/or acute pancreatitis or jaundice in patient's history. Suspected prognostic factors and the combination of factors were compared to the result of ERCRRESULTS: Two hundred and six preoperative ERCPs were performed during the observed period. The rate of successful cannulation for ERC was (97.1%). Bile duct stones were detected in 81 patients (39.3%), and successfully removed in 79 (97.5%). The number of prognostic factors correlated with the presence of bile duct stones. The positive predictive value for one prognostic factor was 1.2%, for two 43%,for three 72.5%, for four or more 91.4%.CONCLUSION: Based on our data preoperative ERCP is highly recommended in patients with three or more positive factors (high risk patients). In contrast, ERCP is not indicated in patients with zero or one factor (low risk patients).Preoperative ERCP should be offered to patients with two positive factors (moderate risk patients), however the practice should also be based on the local conditions (e.g.skill of the endoscopist, other diagnostic tools). | Laszlo Lakatos Gabor Mester Gyorgy Reti Attila Nagy Peter Laszlo Lakatos | 2004 | World Journal of Gastroenterology2004，10，23： | 10 |
| 8 | 在有从 Valsalva 的正确湾穴产生的一根单个冠的动脉的一个病人的急性冠的症候群显示文摘 Coronary artery anomalies are usually encountered as coincidental findings during coronary angiography or at autopsy.Life threatening symptoms,such as arrhythmias,syncope,myocardial infarction,or sudden death,can occur in up to 20% of patients.However,the majority of anomalies(80%) are benign and asymptomatic.A single coronary artery(SCA) is one of the most rarely seen coronary anomalies with an incidence of 0.05%.We report the case of a 55-year old male patient who presented with symptoms of chest pain associated with an acute myocardial infarction.Coronary angiography revealed an anomalous left main coronary artery(LMCA) originating from the right coronary ostium,and an occluded distal right coronary artery.The occluded distal right coronary artery was successfully treated by thrombosuction and stenting.In order to confirm the origin and course of the SCA,multi-slice computed tomography(MSCT) of the heart was performed after coronary angiography.MSCT showed that the anomalous LMCA originated from the right coronary artery ostium and then passed the interventricular septum,instead of being intra arterial,and under the right ventricular infundibulum.The anomalous LMCA was classified as R-Ⅱ S subtype according to Lipton’s classification. | Crista Liesting Jasper Jan Brugts Marcellinus Johannes Maria Kofflard Attila Dirkali | 2012 | World Journal of Cardiology2012，4，8： | 7 |
| 9 | 中国甘肃和青海省叶蜂类六新种记述(膜翅目:叶蜂科)(英文)显示文摘记述了叶蜂科采自甘肃的 3个新种:Tenthredo (Tenthredo) sinotemula sp. nov., Tenthredo (Tenthredella) labrangensis sp. nov.和 Tenthredo (Tenthredella) sinosimplex sp. nov.;采自青海的 3 个新种:Tenthredo (Tenthredella) rolleri sp. nov., Tenthredo (Tenthredella) qinghaiensis sp. nov.和 Tenthredo (Tenthredella) yunningsiensis sp. nov. | Attila Haris | 2009 | Zoological Research2009，30，3： | 6 |
| 10 | Effects of Carbon Content and Solidification Rate on the Thermal Conductivity of Grey Cast Iron显示文摘The thermal conductivity/diffusivity of pearlitic grey irons with various carbon contents was investi- gated by the laser flash method. The materials were cast in controlled thermal environments producing three dissimilar cooling rates. The cooling rates together with the carbon content largely influence the thermal conductivity of grey iron. Linear relationships exist between the thermal conductivity and the carbon content, the carbon equivalent, and the fraction of the former primary solidified austenite transformed into pearlite. The results show that the optimal thermal transport properties are obtained at medium cooling rates. Equa- tions are given for the thermal conductivity of pearlite, solidified as pre-eutectic austenite, and the eutectic of grey iron. The thermal conductivity of pearlitic grey iron is modelled at both room temperature and elevated temperatures with good accuracy. | Daniel Holmgren Attila Diószegi Ingvar L. Svensson | 2008 | Tsinghua Science and Technology2008，13，2： | 5 |
| 11 | 锂离子液流电池电极悬浮液研究进展显示文摘锂离子液流电池将锂离子电池的工作原理与传统液流电池的结构特点相结合,是一种正处于基础技术开发阶段的新型电化学储能电池技术,具有输出功率和储能容量彼此独立、成本较低等特点,适用于未来电网储能领域。电极悬浮液作为实现锂离子液流电池充放电功能的主体材料,其导电性能和流动性能是影响锂离子液流电池倍率特性和能量密度的重要因素。论文结合实验数据对该方向面临的主要技术问题及研究重点进行了分析,认为电极悬浮液的研究需要从导电机理、质量比容量、流变性能等方面进一步深入研究,并建立标准评价体系。 | 冯彩梅 陈永翀 韩立 巩宇 Cserháti Csaba Csik Attila | 2015 | 储能科学与技术2015，4，3： | 5 |
| 12 | Effects of carbon content and solidification rate on thermal conductivity of grey cast iron显示文摘The thermal conductivity or diffusivity of pearlitic grey irons with various carbon contents is investigated by the laser flash method. The materials are cast in controlled thermal environments and produced in three dissimilar cooling rates. The cooling rate together with the carbon content largely influence the thermal conductivity of grey iron. Linear relationships exist between the thermal conductivity and the carbon content,the carbon equivalent and the fraction of former primary solidified austenite transformed into pearlite. The work shows that optimal thermal transport properties are obtained at medium cooling rates. Equations describing the thermal conductivity of pearlite,solidified as pre-eutectic austenite,and the eutectic of grey iron are derived. The thermal conductivity of pearlitic grey iron is modeled at both room temperature and elevated temperature with good accuracy. | Daniel Holmgren Attila Diószegi Ingvar L.Svensson | 2007 | China Foundry2007，4，3： | 5 |
| 13 | Finding a fairy in the forest: ELF4, a novel and critica element of type I interferon responses显示文摘 | Attila Szabo Eva Rajnavolgyi | 2014 | Cellular & Molecular Immunology2014，11，3： | 5 |
| 14 | Patents and innovation counts as measures of regional production of new knowledge显示文摘 | Zoltan J Acs Luc Anselin Attila Varga | 2002 | Research Policy2002，，7： | 4 |
| 15 | 双任务中内隐运动技能学习对提高保持成绩的作用(英文)显示文摘本实验研究的目的是,调查在双任务条件下一个运动系列能否被不觉察地掌握,内隐学习是否比外显学习更有效地增加保持。36名实验对象被随机分为内隐学习组或外显学习组。要求所有被试通过敲击一个键盘上的F和J键,来移动计算机屏幕上的横杆,去接住一个下落的小球。一个固定的5种小球下落曲线的系列被安插在每组15次练习的中段。同时,实验参加者需要数每组练习中的所听到的嘟嘟声的数目,以作为第二项任务。在掌握该技能后的24小时进行3次保持测验。ANOVA分析发现固定小球下落曲线段的接球成绩随着练习的增加而提高,但是练习对随机段没有作用。尽管两种练习条件下,运动技能学习成绩没有差异,但内隐学习组比外显学习组在模拟接球的保持测试和第二项任务中表现较准确。这些结果显示内隐学习是一个改善运动技能长期记忆的有效手段,并且与外显学习相比,它在练习中占用较少的认知资源。 | 赖勤 Ronald J.Benedict Xiaofen D.Keating Attila J.Kovacs | 2009 | 天津体育学院学报2009，24，2： | 4 |
| 16 | Treatment of Common Bile Duct Injuries during Laparoscopic Cholecystectomy: Endoscopic and Surgical Management显示文摘 | Attila Csendes Claudio Navarrete Patricio Burdiles Julio Yarmuch | 2001 | World Journal of Surgery2001，，10： | 4 |
| 17 | The potential application of red mud and soil mixture as additive to the surface layer of a landfill cover system显示文摘Red mud, the by-product of aluminum production, has been regarded as a problematic residue all over the world. Its storage involves risks as evidenced by the Ajka red mud spill,an accident in Hungary where the slurry broke free, flooding the surrounding areas. As an immediate remediation measure more than 5 cm thick red mud layer was removed from the flooded soil surface. The removed red mud and soil mixture(RMSM) was transferred into the reservoirs for storage. In this paper the application of RMSM is evaluated in a field study aiming at re-utilizing waste, decreasing cost of waste disposal and providing a value-added product. The purpose was to investigate the applicability of RMSM as surface layer component of landfill cover systems. The field study was carried out in two steps: in lysimeters and in field plots. The RMSM was mixed at ratios ranging between 0 and 50% w/w with low quality subsoil(LQS) originally used as surface layer of an interim landfill cover. The characteristics of the LQS + RMSM mixtures compared to the subsoil(LQS) and the RMSM were determined by physical–chemical, biological and ecotoxicological methods. The addition of RMSM to the subsoil(LQS) at up to 20% did not result any ecotoxic effect, but it increased the water holding capacity. In addition, the microbial substrate utilization became about triple of subsoil(LQS) after 10 months. According to our results the RMSM mixed into subsoil(LQS) at20% w/w dose may be applied as surface layer of landfill cover systems. | Eva Ujaczki Viktória Feigl Mónika Molnár Emese Vaszita Nikolett Uzinger Attila Erdélyi Katalin Gruiz | 2016 | Journal of Environmental Sciences2016，28，6： | 3 |
| 18 | Autoimmune pancreatitis: Functional and morphological recovery after steroid therapy显示文摘自体免疫的胰腺炎,慢性胰炎的一种最近公认的类型,不在其它地方在它的日本,而是报告是稀罕的是相对不平常的。我们在匈牙利报导自体免疫的胰腺炎的第一个外科手术前地诊断的案例,它对类固醇处理作出回应很好并且提供了这改进的 X 光线照相术、功能的证据。与周期性的腹上部的疼痛和 5-kg 重量损失的 4 月的历史介绍的 62 岁的女性。口头的葡萄糖耐量测试(OGTT ) 显示糖尿病和烘便的弹性硬蛋白酶测试的结果是反常的。Ultrasonography (美国) 和 CT 扫描表明了广泛地扩大的胰,并且内视镜后退 cholangiopancreatography (ERCP ) 有在头和尾巴的长苛评的不规则的主要的胰腺的管。自体免疫的胰腺炎被诊断。病人每天在 32 mg 氢化尼松上被开始。在 4 wk 以后, OGTT 和排泄物的弹性硬蛋白酶测试结果使正常化。重复美国和 CT 扫描揭示了 diffuse 的显著改进胰腺,在重复 ERCP 上胀大,变窄的主要的胰腺的管被看见被改善。因为 AIP 能临床上类似于 pancreatobiliary 恶意,或长期或尖锐的胰腺炎,知道这疾病和它的诊断是重要的。然而在有慢性胰炎的对比,它的症状并且词法并且实验室改变被口头的类固醇治疗完全颠倒。 | László Czakó (E|')va Hegyk(o|¨)zi Attila Pálinkás János Lonovics | 2006 | World Journal of Gastroenterology2006，12，11： | 3 |
| 19 | Renal cell carcinoma metastatic to the pancreas: Results of surgical management显示文摘 | Taylor A. Sohn M.D. Charles J. Yeo M.D. John L. Cameron M.D. Attila Nakeeb M.D. Keith D. Lillemoe M.D | 2001 | Journal of Gastrointestinal Surgery2001，，4： | 3 |
| 20 | Light Triggers the miRNA-Biogenetic Inconsistency for De-etiolated Seedling Survivability in Arabidopsis thaliana显示文摘The shift of dark-grown seedlings into light causes enormous transcriptome changes followed by a dramatic developmental transition.Here,we show that microRNA(miRNA)biogenesis also undergoes regulatory changes during de-etiolation.Etiolated seedlings maintain low levels of primary miRNAs(pri-miRNAs)and miRNA processing core proteins,such as Dicer-like 1,SERRATE,and HYPONASTIC LEAVES 1,whereas during de-etiolation both pri-miRNAs and the processing components accumulate to high levels.However,the levels of most miRNAs do not notably increase in response to light.To reconcile this inconsistency,we demonstrated that an unknown suppressor decreases miRNA-processing activity and light-induced SMALL RNA DEGRADING NUCLEASE 1 shortens the half-life of several miRNAs in de-etiolated seedlings.Taken together,these data suggest a novel mechanism,miRNA-biogenetic inconsistency,which accounts for the intricacy of miRNA biogenesis during de-etiolation.This mechanism is essential for the survival of de-etiolated seedlings after long-term skotomorphogenesis and their optimal adaptation to ever-changing light conditions. | Suk Won Choi Moon Young Ryu Andras Viczian Hyun Ju Jung Gu Min Kim Agustin LArce Natalia PAchkar Pablo Manavella Ulla Dolde Stephan Wenke Attila Molnar Ferenc Nagy Seok Keun Cho Seong Wook Yang | 2020 | Molecular Plant2020，13，3： | 3 |
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