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| 1 | FDG-PET/CT response evaluation during EGFR-TKI treatment in patients with NSCLC显示文摘Over recent years,[18F]-fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography(FDG-PET/CT)has proven its role as a staging modality in patients with non-small cell lung cancer(NSCLC).The purpose of this review was to present the evidence to use FDG-PET/CT for response evaluation in patients with NSCLC,treated with epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKI).All published articles from 1November 2003 to 1 November 2013 reporting on 18FFDG-PET response evaluation during EGFR-TKI treatment in patients with NSCLC were collected.In total 7studies,including data of 210 patients were eligible for analyses.Our report shows that FDG-PET/CT responseduring EGFR-TKI therapy has potential in targeted treatment for NSCLC.FDG-PET/CT response is associated with clinical and radiologic response and with survival.Furthermore FDG-PET/CT response monitoring can be performed as early as 1-2 wk after initiation of EGFR-TKI treatment.Patients with substantial decrease of metabolic activity during EGFR-TKI treatment will probably benefit from continued treatment.If metabolic response does not occur within the first weeks of EGFR-TKI treatment,patients may be spared(further)unnecessary toxicity of ineffective treatment.Refining FDG-PET response criteria may help the clinician to decide on continuation or discontinuation of targeted treatment. | Matthijs H van Gool Tjeerd S Aukema Koen J Hartemink Renato A Valdés Olmos Houke M Klomp Harm van Tinteren | 2014 | World Journal of Radiology2014，6，7： | 8 |
| 2 | A comparison of tools for modeling freshwater ecosystem services显示文摘 | Vigerstol K L Aukema J E | 2011 | Journal of Environmental Management2011，92，10： | 1 |
| 3 | Predicting early chemotherapy response with technetium-99m methoxyisobutylisonitrile SPECT/CT in advanced non-small cell lung cancer显示文摘 | Yang T J Aukema T S van-Tinteren H | 2010 | Mol Imaging Biol2010，12，2： | 1 |
| 4 | Treatment of nasal polyposis and chronic rhinosinusitis with fluticasone propionate nasal drops reduces need for sinus surgery显示文摘 | AUKEMA A A MULDER P G FOKKENS W J | 2005 | J Allergy Clin Immunol2005，115，： | 1 |
| 5 | Variation in mistletoe seed deposition: effects of intra- and interspecific host characteristics 显示文摘 | Aukema J Martinez del Rio C 2002 | 2002 | Ecography2002，25，： | 1 |
| 6 | Vectors, viscin, and Viscaeae: Mistletoes as parasites, mutualists, and resources 显示文摘 | Aukema J 2003 | 2003 | Frontiers in Ecology and the Environment2003，1，： | 1 |
| 7 | Distribution and dispersal of desert mis- tletoe is scale - dependent, hierarchically nested 显示文摘 | AUKEMA J E | 2004 | Ecography2004，27，2： | 1 |
| 8 | Variation in mistletoe seed deposition:effects of intra - and interspecific host characteristics 显示文摘 | AUKEMA J E MARTINEZ C | 2002 | Ecography2002，25，2： | 1 |
| 9 | First clinical experience with a dedicated PET for hanging breast molecular imaging显示文摘 | Koolen B Aukema T S González Martínez A J Vogel W V Caballero Ontanaya L Vrancken Peeters M-JTFD Vroonland C J J Rutgers E J TH Benlloch Baviera JM Valdés Olmos R A | 2013 | The Quarterly Journal of Nuclear Medicine and Molecular Imaging2013，，1： | 1 |
| 10 | Alterations in renal cytosolic phospholipase A2 and cyclooxygenase-2 in polycystic kidney disease显示文摘 | Aukema HM Adolphe J Sishra S | 2003 | FASEB J2003，17，： | 1 |
| 11 | Economic im- pacts of invasive species in forests: past, present and future显示文摘 | HOLMES T P AUKEMA J E ~on HOLLE B at al | 2009 | New York Academy of Sciences2009，1162，： | 1 |
| 12 | 18F-FDG PET/CT as a staging procedure in primary stage II and III breast cancer: comparison with conventional imaging techniques显示文摘 | KOOLEN B B VRANCKEN PEETERS M J AUKEMA T S | 2012 | Breast Cancer Res Treat2012，131，1： | 1 |
| 13 | Treat- ment of nasal polyposis and chronic rhinosinusitis with fluticasone propionate nasal drops reduces need for sinus surgery显示文摘 | AUKEMA A A MULDER P G FOKKENS W J | 2005 | J Allergy Clin Immunol2005，115，5： | 1 |
| 14 | The PCBP1gene encoding Poly(rC)binding protein 1is recurrently mutated in burkitt lymphoma显示文摘 | Wagener R Aukema S M Schlesner M Haake A Burkhardt B Claviez A Drexler H G Hummel M Kreuz M Loeffler M Rosolowski M López C Mller P Richter J Rohde M Betts M J Russell R B Bernhart S H Hoffmann S Rosenstiel P Schilhabel M Szczepanowski M Trümper L Klapper W Siebert R | 2015 | Genes Chromosomes Cancer2015，54，9： | 1 |
| 15 | Chronic rhinosinusitis:management for optimal outcomes显示文摘 | AUKEMA A A FOKKENS W J | 2004 | Treat Respir Med2004，3，： | 1 |
| 16 | Chronic rhinosinusitis: management for optimal outcomes显示文摘 | Aukema A A Fokkens W J Bhattaeharyya N | 2004 | Treat Respir Med2004，3，2： | 1 |
| 17 | White matter frac- tional anisotropy correlates with speed of processing and motor speed in young childhood cancer survivors 显示文摘 | Aukema E J Caan MW Oudhuis N | 2009 | Int J Radiat On- col Biol Phys2009，74，3： | 1 |
| 18 | Distinctive effects of plant protein sources on renal disease progression and associated cardi- ac hypertrophy in experimental kidney disease 显示文摘 | Aukema HM Ganthier J Roy M | 2011 | MolNutr Food Res2011，55，7： | 1 |
| 19 | Economic Impacts of Invasive species in forests:past,present and future显示文摘 | Holmes T P Aukema J E Holle B V | 2009 | New York Academy of Sciences2009，1162，： | 1 |
| 20 | Predicting early chemotherapy response with technetium- 99m methox~isobutylisonitrile SPECT/CT in advanced non-small cell lung cancer 显示文摘 | YANG T J AUKEMA T S VAN TINTEREN H | 2010 | Mol Imaging Biol2010，12，2： | 1 |
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