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27篇 您的检索式:作者名="Aweya"
    题名 作者 年代 出处 被引量
1Understanding the interaction of hepatitis C virus with host DEAD-box RNA helicases显示文摘The current therapeutic regimen to combat chronic hepatitis C is not optimal due to substantial side effects and the failure of a significant proportion of patients to achieve a sustained virological response.Recently developed direct-acting antivirals targeting hepatitis C virus(HCV)enzymes reportedly increase the virologic response to therapy but may lead to a selection of drug-resistant variants.Besides directacting antivirals,another promising class of HCV drugs in development include host targeting agents that are responsible for interfering with the host factors crucia for the viral life cycle.A family of host proteins known as DEAD-box RNA helicases,characterized by nine conserved motifs,is known to play an important role in RNA metabolism.Several members of this family such as DDX3,DDX5 and DDX6 have been shown to play a role in HCV replication and this review will summarize our current knowledge on their interaction with HCV.As chronic hepatitis C is one of the leading causes of hepatocellular carcinoma,the involvement of DEADbox RNA helicases in the development of HCC will also be highlighted.Continuing research on the interaction of host DEAD-box proteins with HCV and the contribution to viral replication and pathogenesis could be the panacea for the development of novel therapeutics against HCV.Megha Haridas Upadya Jude Juventus Aweya Yee-Joo Tan 2014World Journal of Gastroenterology2014,20,11:6
2IP router architectures: an overview显示文摘Aweya J 2001International Journal of Communication Systems2001,14,5:1
3A control theoretic approach to active queue management显示文摘AWEYA J OUELLETTE M MONTUNO D Y 2001Computer Networks2001,36,23:1
4A comparison of active queue management algorithms using the OPNET modeler显示文摘ZHU C YANG O AWEYA J 2002IEEE Commun Mag2002,40,6:1
5Multi-level active queue management with dynamic thresholds显示文摘Aweya J 2002Computer Communications Journal (Elsevier Science)2002,25,8:1
6Circuit emulation services over Ethernet-part 1:clock synchronization using timestamps显示文摘AWEYA J OUELLETTE M MONTUNO D Y 2004International Journal of Network Management2004,14,1:1
7An adaptive load balancing scheme for Web servers 显示文摘AWEYA J OUELETTE M MONTUNO D Y 2002International Journal of Network Management2002,12,1:1
8IP Router Architectures: An Overview显示文摘Aweya J 1999Journal of Systems Architecture1999,46,2000:1
9A control theoretic approach to active queue management 显示文摘AWEYA J OUELLETTE M MONTUNO D Y 2001Computer Network2001,36,2:1
10On the design of IP routers,part 1:router architectures显示文摘AWEYA J 2000Journal of Systems Architecture2000,46,6:1
11Proportional loss rate differentiation in a FIFO queue显示文摘AWEYA J OUELLETTE M MONTUNO O Y 2004Computer Communications2004,27,18:1
12Weighted proportio-nal loss rate differentiation of TCP traffic显示文摘AWEYA J OUELLETTE M MONTUNO O Y 2004International Journal of Network Management2004,14,4:1
13Relative loss rate differentiation:performance of short-lived TCP flows显示文摘AWEYA J OUELLETTE M MONTUNO O Y 2005International Journal of Communication Systems2005,18,1:1
14A adaptive load balancing schemefor web servers显示文摘James Aweya Michel Ouellette Delfin Y M-ontuno 2002Network Mgmt2002,,2:1
15A Control Theoretic Approach to Active Queue Management显示文摘AWEYA J OUELLETTE M MONTUNO D Y 0,,2:1
16Technique for differential timing transfer over packet networks显示文摘Aweya J 0,,1:1
17Comparison of Active Queue Management Algorithms Using the OPNET Modeler显示文摘ZHU C Y AWEYA J OUELLETTE M 2002IEEE Communications Magazine2002,40,6:1
18DRED:a random early detection algorithm for TCP/IP networks显示文摘Aweya J Ouellette M Montuno D Y 2002International Journal of Communication Systems2002,15,4:1
19Circuit emulation services over Ethernet-Part 1 : Clock synchronization using timestamps 显示文摘James Aweya Michel Ouetlette Delfin Y Montuno and Kent Felske 2004Internal Journal of Network Management2004,,14:1
20IP Router architectures:an overview显示文摘Aweya J 2000Journal of System Architecture2000,,46:1
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