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2篇 您的检索式：作者名="Aydin Rustemoglu"

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		题名	作者	年代	出处	被引量
	1	Effects of interleukin (IL)-6 gene poly- morphisms on recurrent aphthous stomatitis显示文摘	Nevin Karakus Serbulent Yigit Aydin Rustemoglu Goknur Kalkan Nihan Bozkurt	2014	Archives of Derma- tological Research2014，2，：	1
	2	Significance of IL-1Ra and IL-6 gene variants in Turkish patients with Crimean-Congo hemorrhagic fever显示文摘Objective: To investigate the association between IL-1 Ra variable number of tandem repeat(rs2234663), IL-6-597 GA(rs1800797), IL-6-572 GC(rs1800796) and the risk of CrimeanCongo hemorrhagic fever(CCHF) in the Turkish patients. Methods: This study included 50 patients infected with CCHF and 50 healthy controls. These variants were genotyped using polymerase chain reaction and/or restriction fragment length polymorphism method. Results: The distribution of the IL-6-572 GC genotypes and alleles varied significantly between the patients and the controls. The subjects carrying IL-6-572 GC GG genotype and G allele had increased risk of developing CCHF compared to the control group(P=0.006, P=0.014, respectively). IL-6-572 GC GC genotype was higher in the controls than the patients(P=0.006). For the triple genotype combinations, the 1/2-GC-GG genotype combination was detected more frequently in the control group than CCHF patients(P=0.016). IL-6(-572/-597) GG-GG genotype was significantly higher in the patient group(P=0.015), while the GC-GG genotype was significantly lower in the patient group(P=0.005). Additionally, the G-G haplotype was significantly higher in the patient group(P=0.042), whereas C-G was found to be significantly lower in the patients than the control group(P=0.037). Conclusions: The results of this study suggest the IL-6-572 GC variant might be genetic markers of sensitivity to CCHF in the Turkish population and may facilitate greater protection against the disease.	Umut Safiye Say Coskun Ayse Feyda Nursal Ferdi Gunes Aydin Rustemoglu Abdullah Yayli Nevin Karakus Huseyin Sener Barut Serbulent Yigit	2019	Asian Pacific Journal of Tropical Biomedicine2019，9，2：	0

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