| 2 | Prediabetes and cardiovascular complications study:Highlights on gestational diabetes, self-management and primary health care显示文摘International collaboration on the prediabetes and cardiovascular complications study started in 2013.In 2017,a reflection was reported.Incompleteness of documentation and screening of antenatal cases for gestational diabetes mellitus(GDM)was concerning.Hence,further observations have been made that warrant an update.The objective of this review is to highlight gaps between clinical knowledge and practice in GDM,diabetes self-management and primary health care(PHC)for rural dwellers.We followed a descriptive field notes method.Antenatal records of patients screened for GDM with incomplete documentation were examined to determine incompleteness of data in those that also met the criteria for GDM risk assessment.Experiences on development of a diabetes register and education and notes on behavioural change wheel were also reviewed.Other data included cross-sectional evaluation of activities of daily living at two private hospitals.Up to 29%had high GDM risk factors,which fulfilled selection criteria for laboratory screening.Demographic data was complete in all women;however,incomplete documentation was observed with as much as 98%of basic data.High levels of physical activity were found in the population,and health lectures proved effective in food choices.The workforce need for diabetes care seems underestimated,but this may be better understood with reactivation of PHC services.The observations highlight behavioural change wheel issues on GDM and PHC services that need concerted focus.Two proposals are to advance the use of a‘risk assessment and screening sheet’for GDM screening and enlightenment of stakeholders on the central hub role of PHC in diabetes management. | Ezekiel Uba Nwose Phillip Taderera Bwititi Otovwe Agofure Echinei Jacob Oshionwu Ekenechukwu Esther Young Eferhire Aganbi Solomon Ekwuweokwuenu Egwenu Helen Egoyibo Chime Fortunatus Darius Gbeinbo Alex Odufu John Nwakaego Okuzor Azuka Okuleye Kennedy Aninze Innocent Chuks Onyia Euzebus Chinonye Ezugwu Eunice Obiajuru Igumbor Ifeoma Isabel Ulasi | 2021 | World Journal of Meta-Analysis2021，9，6： | 1 |
| 3 | HPV prevalent types in a cohort of sexually active Nigerian women:implications for vaccination programmes显示文摘Background:The human papillomavirus virus(HPV)is very common with over 150 strains and at least 42 acquired by sexual contact.It is a public health concern among women the world over,with an estimated prevalence of 11.7%globally,and 24%in Sub-Saharan Africa.There are five common HPV types;HPV16,HPV18,HPV52,HPV31,and HPV58.Cervical cancer affects women globally,with estimated 570,000 new cases in 2018.Nearly 90%of the 311,000 deaths worldwide in that year occurred in low-and middle-income countries.Objective:To estimate the prevalence of HPV among sexually active women in Lagos,Nigeria;and to determine the most common HPV type among that category.Methods:A descriptive cross-sectional study design was implemented,with 198 women in total enrolled for the study.Sexually active women from various health facilities in Lagos were screened by obtaining cervical tissue,stirred into PCR cell media,and assayed for HPV genotypes using the Roche COBAS®4800 System.Results:Age of the women ranged from 18 to 65 years(mean 34.6±6.4),with the majority(56.4%)between 25-34 years;65%were married and 63%had a secondary education.Age at first penile-vaginal contact ranged from 9 to 38 years(mean 20.4±3.9).Sixty-five percent of women stated total lifetime sexual partners of between 2 and 4(mean 2.9±2.5).The prevalence of high-risk HPV was 40.4%(95%CI:40.1 to 40.7)and breakdown of types obtained were;HPV16,2.5%(95%CI:2.22 to 2.78);HPV18,3.5%(95%CI:3.22 to 3.78);other high risk(OHR)HPV,28.3%(95%CI:28 to 28.6);HPV16&OHR HPV,1.5%(95%CI:1.22 to 1.78);HPV18&OHR HPV,4.1%(95%CI:3.82 to 4.38);HPV16,18&OHR HPV,0.5%(95%CI:0.221 to 0.779).HPV negative and inconclusive results were 58.1%and 1.5%respectively.Conclusion:Prevalence of OHR HPV is high among Nigerian women.This informs the pattern of HPV existing in the African region,and may aid future efforts at eradicating the virus.The findings are further contributive evidence to the initiative to eliminate cervical cancer as a public health challenge in Nigeria. | Azuka Patrick Okwuraiwe Rosemary Ajuma Audu Titiola Abike Gbajabiamila Ifeoma Eugenia Idigbe Oliver Chukwujekwu Ezechi | 2021 | Precision Medicine Research2021，3，3： | 0 |
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