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| 1 | Crohn's disease with gastroduodenal involvement: Diagnostic approach显示文摘Crohn's disease(CD) is a chronic idiopathic inflammatory disease of gastrointestinal tract characterizedby segmental and transmural involvement of gastrointestinal tract. Ileocolonic and colonic/anorectal is a most common and account for 40% of cases and involvement of small intestine is about 30%. Isolated involvement of stomach is an extremely unusual presentation of the disease accounting for less than 0.07% of all gastrointestinal CD. To date there are only a few documented case reports of adults with isolated gastric CD and no reports in the pediatric population. The diagnosis is difficult to establish in such cases with atypical presentation. In the absence of any other source of disease and in the presence of nonspecific upper gastrointestinal endoscopy and histological findings, serological testing can play a vital role in the diagnosis of atypical CD. Recent studies have suggested that perinuclear anti-neutrophil cytoplasmic antibody and anti-Saccharomycescervisia antibody may be used as additional diagnostic tools. The effectiveness of infliximab in isolated gastric CD is limited to only a few case reports of adult patients and the long-term outcome is unknown. | Sachin B Ingle Baban D Adgaonkar Nawab P Jamadar Saleha Siddiqui Chitra R Hinge | 2015 | World Journal of Clinical Cases2015,3,6: | 5 |
| 2 | Microscopic colitis: Common cause of unexplained nonbloody diarrhea显示文摘Microscopic colitis(MC) is characterized by chronic, watery, secretory diarrhea, with a normal or near normal gross appearance of the colonic mucosa. Biopsy is diagnostic and usually reveals either lymphocytic colitis or collagenous colitis. The symptoms of collagenous colitis appear most commonly in the sixth decade. Patients report watery, nonbloody diarrhea of a chronic, intermittent or chronic recurrent course. With collagenous colitis, the major microscopic characteristic is a thickened collagen layer beneath the colonic mucosa, and with lymphocytic colitis, an increased number of intraepithelial lymphocytes. Histological workup can confirm a diagnosis of MC and distinguish the two distinct histological forms, namely, collagenous and lymphocytic colitis. Presently, both forms are diagnosed and treated in the same way; thus, the description of the two forms is not of clinical value although this may change in the future. Since microscopic colitis was first described in 1976 and only recently recognized as a common cause of diarrhea, many practicing physicians may not be aware of this entity. In this review, we outline the epidemiology, risk factors associated with MC, its etiopathogenesis, the approach to diagnosis and the management of these individuals. | Sachin B Ingle Baban D Adgaonkar Chitra R Hinge(Ingle) | 2014 | World Journal of Gastrointestinal Pathophysiology2014,5,1: | 2 |
| 3 | Plasmacytoid dendriticcells from mouse tumor-draining lymph nodes directly activate matureTregs via indoleamine 2,3-dioxygenase显示文摘 | Sharma MD Baban B Chandler P | 2007 | J Clin Invest2007,117,9: | 1 |
| 4 | IDO activates regulatory T cells and blocks their conversion into Thl7-1ike T cells 显示文摘 | Baban B Chandler PR Sharma MD | 2009 | J Immunol2009,183,4: | 1 |
| 5 | GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2, 3--dioxygenase显示文摘 | Munn DH Sharma MD Baban B | 2005 | Immunity2005,225,: | 1 |
| 6 | Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase显示文摘 | Mellor AL Chandler P Baban B | 2004 | Int Immunol2004,16,10: | 1 |
| 7 | Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire poment indoleamine 2,3 - dioxygenase - de- pendent T cell regulatory functions via IFN Type 1 signa- ling显示文摘 | Mellor AL Baban B Chandler PR | 2005 | J Immunol2005,175,9: | 1 |
| 8 | GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3 -dioxygenase 显示文摘 | Munn DH Sharma MD Baban B | 2005 | Immunity2005,22,5: | 1 |
| 9 | Cutting edge:CpG oligonucleotides induce splenic CDl9+dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling显示文摘 | MELLOR AL BABAN B CHANDLER PR | 2005 | J Immunol2005,175,9: | 1 |
| 10 | Possible improved survival of patients with stage Ⅳ AJCC melanoma receiving SRL 172 immunotherapy: correlation with induction of increased levels of intracellular interleukin-2 in peripheral blood lymphocytes 显示文摘 | Maraveyas A Baban B Kennard D | 1999 | Ann Oncol1999,10,7: | 1 |
| 11 | A minor population of splenic dendritic cells expressing CD 19 mediates IDOdependent T cell suppression Ilia type I IFN signaling following B7Iigation显示文摘 | Baban B Hansen AM Chandler PR | 2005 | Int Immunol2005,17,7: | 1 |
| 12 | GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase 显示文摘 | Munn DH Sharma MD Baban B | 2005 | Immunity2005,22,5: | 1 |
| 13 | GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase 显示文摘 | Munn DH Sharma MD Baban B | 2005 | Immunity2005,22,5: | 1 |
| 14 | Cutting edge : induced indoleamine 2, 3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion显示文摘 | Mellor AL Baban B Chandler P | 2003 | J Immunol2003,171,4: | 1 |
| 15 | Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase 显示文摘 | Mellor AL Chandler P Baban B | 2004 | Int Immunol2004,16,10: | 1 |
| 16 | Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase 显示文摘 | Sharma MD Baban B Chandler P | 2007 | J Clin Invest2007,117,9: | 1 |
| 17 | GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenaae显示文摘 | Munn DH Sharma MD Baban B | 2005 | Immunity2005,22,5: | 1 |
| 18 | Female spontaneously hyper- tensive rats have a compensatory increase in renal regulatory T cells in response to elevations in blood pressure显示文摘 | Tipton AJ Baban B Sullivan JC | 2014 | Hyperten sion2014,64,3: | 1 |
| 19 | Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase显示文摘 | Mellor AL Chandler P Baban B | 2004 | Int Immunol2004,16,10: | 1 |
| 20 | Endoplasmic reticulum stress response and inflammatory cytokines in type 2 diabetic nephropathy : role of indoleamine 2, 3-dioxygenase and programmed death-l显示文摘 | Baban B Liu JY Mozaffari MS | 2013 | Exp Mol Pathol2013,94,: | 1 |