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| 1 | Circular smooth muscle contributes to esophageal shortening during peristalsis显示文摘AIM:To study the angle between the circular smooth muscle(CSM) and longitudinal smooth muscle(LSM) fibers in the distal esophagus.METHODS:In order to identify possible mechanisms for greater shortening in the distal compared to proximal esophagus during peristalsis,the angles between the LSM and CSM layers were measured in 9 cadavers.The outer longitudinal layer of the muscularis propria was exposed after stripping the outer serosa.The inner circular layer of the muscularis propria was then revealed after dissection of the esophageal mucosa and the underlying muscularis mucosa.Photographs of each specimen were taken with half of the open esophagus folded back showing both the outer longitudinal and inner circular muscle layers.Angles were measured every one cm for 10 cm proximal to the squamocolumnar junction(SCJ) by two independent investigators.Two human esophagi were obtained from organ transplant donors and the angles between the circular and longitudinal smooth muscle layers were measured using micro-computed tomography(micro CT) and Image J software.RESULTS:All data are presented as mean ± SE.The CSM to LSM angle at the SCJ and 1 cm proximal to SCJ on the autopsy specimens was 69.3 ± 4.62 degrees vs 74.9 ± 3.09 degrees,P = 0.32.The CSM to LSM angle at SCJ were statistically significantly lower than at 2,3,4 and 5 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 82.58 ± 1.34 degrees,84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.013,P = 0.008,P = 0.004,P = 0.009 respectively.The CSM to LSM angle at SCJ was also statistically significantly lower than the angles at 6,7 and 8 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 80.18 ± 2.09 degrees,81.81 ± 1.75 degrees and 80.96 ± 2.04 degrees,P = 0.05,P = 0.02,P = 0.03 respectively.The CSM to LSM angle at 1 cm proximal to SCJ was statistically significantly lower than at 3,4 and 5 cm proximal to the SCJ,74.94 ± 3.09 degrees vs 84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.019,P = 0.008,P = 0.02 respectively.At 10 cm above SCJ the angle was 80.06 ± 2.13 degrees which is close to being perpendicular but less than 90 degrees.The CSM to LSM angles measured on virtual dissection of the esophagus and the stomach on micro CT at the SCJ and 1 cm proximal to the SCJ were 48.39 ± 0.72 degrees and 50.81 ± 1.59 degrees.Rather than the angle of the CSM and LSM being perpendicular in the esophagus we found an acute angulation between these two muscle groups throughout the lower 10 cm of the esophagus.CONCLUSION:The oblique angulation of the CSM may contribute to the significantly greater shortening of distal esophagus when compared to the mid and proximal esophagus during peristalsis. | Anil K Vegesna Keng-Yu Chuang Ramashesai Besetty Steven J Phillips Alan S Braverman Mary F Barbe Michael R Ruggieri Larry S Miller | 2012 | World Journal of Gastroenterology2012,18,32: | 7 |
| 2 | Leptin:A metabolic signal affecting centrtal regualation of reproduction in the pig显示文摘 | Hausman GJ Czaja K | 2005 | Domest Anim Endocrinol2005,29,1: | 1 |
| 3 | Predictive factors of outcome and hemorrhage after acute ischemic stroke treated by mechanical thrombectomy with a stent-retriever显示文摘 | Soize S Barbe C Kadziolka K | 2013 | Neuroradiology2013,55,8: | 1 |
| 4 | Cytokines and acute phase pro- teins associated with acute swine influenza infection in pigs 显示文摘 | Barbe F Atanasova K Van R | 2011 | Veteri- nary Journal2011,187,: | 1 |
| 5 | Prolonged cyclooxygenase-2 induction in neurons and glia following traumatic brain injury in the rat显示文摘 | Strauss K I Barbe M F Marshall R M | 2000 | J Neurotraama2000,17,8: | 1 |
| 6 | The HITRAN 2008 molecular spectroscopic database 显示文摘 | Rothman L S Gordon I E Barbe A ChrisBenner D Bernath P F Birk M Boudon V Brown L R Campargue A Champi-on J P Chance K Coudert L H Dana V Devi V M Fally S Flaud J M Gamache R R Goldman A Jacquemart D Klein er I Lacome N Lafferty W J Mandin J Y Massie S T Mikhailenko S N Miller C E Moazzen A N Naumenko 0 VNikitin A V Orphal J Perevalov V I Perrin A Predoi C A Rinsland C P Rotger M ime kovd M Smith M A H Sung K Tashkun S A Tennyson J Toth R A Vandaele A C Vander A J | 2009 | Journal of Quantitative Spectroscopy Radiative Transfer2009,110,: | 1 |
| 7 | Formation ofsilica nanoparticles in microemulsions显示文摘 | Finnie K S Bartlett J R Barbe CJA | 2007 | Langmuir2007,23,6: | 1 |
| 8 | nFrequency-Domain,Errors-in-Variables Estima-tion of Linear Dynamic Systems Using Data From Overlap-ping Subrecords,11 Instrumentation and Measurement显示文摘 | Barbe K | 2008 | IEEE Transactions on2008,,57: | 1 |
| 9 | Cognitive radios:discriminate analysis finds the free space显示文摘 | LEE G F BARBE K VANMOER W | 2013 | IEEE Transactionson Communication2013,32,4: | 1 |
| 10 | Prolonged cyclooxygenase-2 induction in neurons and glia following traumatic brain injury in the rat显示文摘 | STRAUSS K I BARBE M F MARSHALL R M | 2000 | J Neurotrauma2000,17,8: | 1 |
| 11 | Effect of cysteamine hydrochloride on secretion of growth hormone in male swine显示文摘 | MCELWAIN K V ESTIEMME M J BARB C R | 1999 | Life Sci1999,64,24: | 1 |
| 12 | Biology of leptin inthe pig显示文摘 | BARB C R HAUSMAN G J HOUSEKNECHT K L | 2001 | Domestic Animal Endocrinology2001,21,: | 1 |
| 13 | Polyunsaturated fatty acidsas antioxidants显示文摘 | Richard D Kefi K Barbe U | 2008 | Pharmacological Research2008,57,6: | 1 |
| 14 | Adaptations of skeletal muscle to exercise rapid increase in the transcriptional coactivator PGC-1α显示文摘 | BARB K ANDM R | 2002 | FASEB Dec2002,16,: | 1 |
| 15 | Silica particles:a novel drug-delivery system显示文摘 | Barbe C Bartlett J Linggen K | 2004 | Adv Mater2004,16,21: | 1 |
| 16 | Rapid immunoaffinity - based method for determination of zearalenane in corn by fluorometry and liquid chromatography显示文摘 | Scott CK Barb K Catherine SR | 1999 | J AOAC Int1999,82,: | 1 |
| 17 | Poly- unsaturated fatty acids as antioxidants显示文摘 | Richard D Kefi K Barbe U Bausero P Visioli F | 2008 | Pharmacol Res2008,57,: | 1 |
| 18 | Sol-gel matrices for controlled release: from macro to nano using emulsion polymerisation 显示文摘 | Barb C J Kong L Finnie K S | 2008 | Journal of SogGel Science Technology2008,46,: | 1 |
| 19 | Leptin:A metabolic signal affecting centrtal regualation of reproduction in the pig显示文摘 | Hausman G J Czaja K | 2005 | Domest Anim Endocrino12005,29,1: | 1 |
| 20 | Leptin:a metabolic signal affecting central regulation of reproduction in the pig显示文摘 | BARB C R HAUSMAN G J CZAJA K | 2005 | Domestic Animal Endocrinology2005,29,: | 1 |