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| 1 | A single subcutaneous dose of tramadol for mild to moderate musculoskeletal trauma in the emergency department显示文摘BACKGROUND: Mild to moderate musculoskeletal trauma is a common cause for an emergency room visit, and frequent pain is one of the cardinal symptoms of consultation. The objective of this study is to assess the perception of a single subcutaneous dose of 50 mg tramadol for pain management in patients with mild to moderate musculoskeletal trauma, likewise to appraise the perception of pain by subcutaneous injection.METHODS: A total of 77 patients, who met inclusion criteria, received a single subcutaneous dose of tramadol. Pain control was evaluated based on the verbal numerical pain scale(0–10) at baseline, 20 and 60 minutes; similarly, pain perception was evaluated secondary to subcutaneous injection of the analgesic.RESULTS: On admission, the average pain perceived by patients was 8; twenty minutes later, 89% of the patients reported fi ve or less, and after sixty minutes, 94% had three or less on the verbal numerical pain scale. Of the patients, 88% reported pain perception by verbal numeric scale of 3 or less by injection of the drug, and 6.5% required a second analgesic for pain control. Two events with drug administration(soft tissue infection and mild abdominal rectus injection) were reported.CONCLUSION: We conclude that a single subcutaneous dose of tramadol is a safe and effective option for the management of patients with mild to moderate pain and musculoskeletal disease in the emergency department. | Alejandro Cardozo Carlos Silva Luis Dominguez Beatriz Botero Paulo Zambrano Jose Bare?o | 2014 | World Journal of Emergency Medicine2014，5，4： | 2 |
| 2 | Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1 alpha 显示文摘 | Gerhart-Hines Z Rodgers JT Bare O | 2007 | EMBO J2007，26，7： | 1 |
| 3 | Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha显示文摘 | Gerhart-Hines Z Rodgers J T Bare O | | 0，，07： | 1 |
| 4 | Metabolic control of muscle mitoehondrial function and fatty acid oxidation through SIRT1/PGC-lalpha显示文摘 | Gerhart-Hines Z Rodgers JT Bare O | 2007 | EMBO J2007，26，7： | 1 |
| 5 | Metabolic control of muscle mitochondrial function and fatty acid oxida-tion through SIRT1/PGC-1alpha显示文摘 | Gerhart-Hines Z Rodgers JT Bare O | 2007 | EMBO J2007，26，7： | 1 |
| 6 | Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study 显示文摘 | Shiffman D O' Meara ES Bare LA | 2008 | Arterioscler Thromb Vasc Biol2008，28，1： | 1 |
| 7 | Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study显示文摘 | Shiffman D O'Meara ES Bare LA et ai | 2008 | Arterioscler Thromb Vase Biol2008，28，1： | 1 |
| 8 | Persistent organochlorine compounds in soils and sediments of European high altitude mountain lakes 显示文摘 | O JOAN GRIMALT L BARE D V DROOGE | 2004 | Chemosphere 542004，，： | 1 |
| 9 | Identification of the accessory nerve by its relationship to the great auricular nerve 显示文摘 | Baring DE Johnston A O'Reilly BF | 2007 | J Laryngol Otol2007，121，9： | 1 |
| 10 | Tuberculosis drug-resist- ance and treatment outcomes under DOTS settings in large city in the Philippines显示文摘 | Ohkado A Aguiman L Adlawan S Baring E Quirante O Su- chi M Endo S Fujiki A Mori T | 2006 | Int J Tuberc Lung Dis2006，10，： | 1 |
| 11 | Metabolic control of muscle mitoehondrial function and fatty acid oxidation through sirT1/PGC-1α显示文摘 | GERHART-HINES Z RODGERS J T BARE O | 2007 | The EMBO Journal2007，26，7： | 1 |
| 12 | Metabolic control of muscle mitochondrial function and fatty acid oxidation throughSIRT1/PGC-1α显示文摘 | Gerhart-Hines Z Rodgers JT Bare O | 2007 | EMBO J2007，26，7： | 1 |
| 13 | Fluorescent-activated droplet sorting(FADS) : efficient microfluidic cell sorting based on enzymatic activity显示文摘 | Bare J C Miller O J Taly V | 2009 | Lab Chip2009，9，13： | 1 |
| 14 | Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study显示文摘 | Shiffman D O'Meara ES Bare LA | 2008 | Arterioscler Thromb Vasc Biol2008，28，： | 1 |
| 15 | Metabolic control of muscle mitochondrial function and fatty acid oxidation through S1RTI/PGC-lalpha显示文摘 | Gerhart-Hines Z Rodgers JT Bare O | 2007 | EMBO J2007，26，7： | 1 |
| 16 | Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/ PGC-lalpha显示文摘 | Gerhart-Hines Z Rodgers JT Bare O | 2007 | EMBO J2007，26，7： | 1 |
| 17 | Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-lalpha显示文摘 | Gerhart-Hines Z Rodgers JT Bare O | 2007 | EMBO J2007，26，7： | 1 |
| 18 | Metabolic control of muscle mitoehondrial function and fatty acid oxidation through SIRT1/PGC-lalpba显示文摘 | Gerhart-Hines Z Rodgers JT Bare O | 2007 | EMBO2007，26，7： | 1 |
| 19 | Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study显示文摘 | Shiffman D OMeara ES Bare LA | 2008 | Arterioscler Thromb Vasc Biol2008，28，1： | 1 |
| 20 | Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study显示文摘 | Shiffman D O'Meara ES Bare LA | | 0，，01： | 1 |
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