|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | High prevalence of hepatic steatosis and vascular thrombosis in COVID-19:A systematic review and meta-analysis of autopsy data显示文摘BACKGROUND Coronavirus disease 2019(COVID-19)disease can frequently affect the liver.Data on hepatic histopathological findings in COVID-19 is scarce.AIM To characterize hepatic pathological findings in patients with COVID-19.METHODS We conducted a systematic review with meta-analysis registered on PROSPERO(CRD42020192813),following PRISMA guidelines.Eligible trials were those including patients of any age and COVID-19 diagnosis based on a molecular test.Histopathological reports from deceased COVID-19 patients undergoing autopsy or liver biopsy were reviewed.Articles including less than ten patients were excluded.Proportions were pooled using random-effects models.Q statistic and I2 were used to assess heterogeneity and levels of evidence,respectively.RESULTS We identified 18 studies from 7 countries;all were case reports and case series from autopsies.All the patients were over 15 years old,and 67.2%were male.We performed a meta-analysis of 5 studies,including 116 patients.Pooled prevalence estimates of liver histopathological findings were hepatic steatosis 55.1%[95%confidence interval(CI):46.2-63.8],congestion of hepatic sinuses 34.7%(95%CI:7.9-68.4),vascular thrombosis 29.4%(95%CI:0.4-87.2),fibrosis 20.5%(95%CI:0.6-57.9),Kupffer cell hyperplasia 13.5%(95%CI:0.6-54.3),portal inflammation 13.2%(95%CI:0.1-48.8),and lobular inflammation 11.6%(95%CI:0.3-35.7).We also identified the presence of venous outflow obstruction,phlebosclerosis of the portal vein,herniated portal vein,periportal abnormal vessels,hemophagocytosis,and necrosis.CONCLUSION We found a high prevalence of hepatic steatosis and vascular thrombosis as major histological liver features.Other frequent findings included portal and lobular inflammation and Kupffer cell hyperplasia or proliferation.Further studies are needed to establish the mechanisms and implications of these findings. | Luis Antonio Díaz Francisco Idalsoaga Macarena Cannistra Roberto Candia Daniel Cabrera Francisco Barrera Alejandro Soza Rondell Graham Arnoldo Riquelme Marco Arrese Michael D Leise Juan Pablo Arab | 2020 | World Journal of Gastroenterology2020，26，48： | 3 |
| 2 | Antioxidant sally a- nalysis re prevents gentamicin-induced oxidative Stress and re- nal damage显示文摘 | Maldonado P D Barrera D Riverd I | 2003 | Free Radic Biol Med2003，35，3： | 1 |
| 3 | Copolymerization and degradation of poly (lactic acid-co-lysine)显示文摘 | BARRERA D A ZYLSTRA E LANSBURY P T | 1997 | Macromolecules1997，25，8： | 1 |
| 4 | The degradation of optical properties in a sulfuric acid anodized aluminum coating system exposed to vacuum or vacuum-ultraviolet radiation显示文摘 | Sheng X Y Callahan D L Barrera E V | 1997 | Materials and Manufacturing Process1997，12，2： | 1 |
| 5 | GLP-1 and energy balance: an integrated model of short-term and long-term control显示文摘 | Barrera JG Sandoval DA D'Alessio DA | 2011 | Nat Rev Endocrinol2011，7，9： | 1 |
| 6 | Phase Ⅱ trial of nanoparticie albumin-bound paclitaxel,carboplatin,and bevacizumab in firstline patients with advanced nonsquamous non-small cell lung cancer 显示文摘 | Reynolds C Barrera D Jotte R | 2009 | J Thorac Oncol2009，4，12： | 1 |
| 7 | Phase II trial of nanoparticle albumin-bound paclitaxel, carboplatin, and bevacizumab in first-line patients with advanced non- squamous non-small cell lung cancer显示文摘 | Reynolds C Barrera D Jotte R | 2009 | J Thorac On- col2009，4，12： | 1 |
| 8 | S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentami- cin-induced oxidative and nitrosative stress and renal dam- age in vivo 显示文摘 | PEDRAZA-CHAVERR J BARRERA D MALDONADO P D | 2004 | BMC Pharmacology and Toxicology2004，4，1： | 1 |
| 9 | GLP-1 and energy balance:an integrated model of short-term and long-term control显示文摘 | Barrera JG Sandoval DA D'Alessio DA | 2011 | Nat Rev Endocrinol2011，7，9： | 1 |
| 10 | The chronic illness resources survey: cross -validation and sensitivity to intervention显示文摘 | Glasgow RE Toobert D J Barrera Jr M | 2005 | Health Educ Res2005，20，4： | 1 |
| 11 | Seasonal variation in insulin sensitivity in healthy elderly 9eople显示文摘 | Bunout D Barrera G delaMaza P | 2003 | Nutrition2003，19，4： | 1 |
| 12 | 4 -Hydroxyeoumarin disorganizes the actin cytoskeleton in B16- F10 melanoma cells but not in B82 fibroblasts, decrea- sing their adhesion to extracellular matrix proteins and motility 显示文摘 | Velasco - Velazquez M A Agramonte - Hevia J Barrera D | 2003 | Cancer Letter2003，198，2： | 1 |
| 13 | A marked difference in pathogenesis and immune response induced by different Mycobacterium tuberculosis genotypes显示文摘 | López B Aguilar D Orozco H Burger M Espitia C Ritacco V Barrera L Kremer K Hernandez-Pando R Huygen K van Soolingen D | 2003 | Clin Exp Immunol2003，133，1： | 1 |
| 14 | Recognition of bacteriophage Qβ plus strand RNA as a template by Qβ replicase:role of RNA interactions mediated by ribosomal proteins S1 and host factors显示文摘 | MIRANDA G SCHUPPLI D BARRERA I | 1997 | Journal of Molecular Biology1997，267，： | 1 |
| 15 | Statistical approach for congestion control in gateway routers显示文摘 | Barrera I D Arce G R Bohacek S | 2011 | Computer Networks2011，55，3： | 1 |
| 16 | Vesicular stomatitis显示文摘 | Letchworth G J Rodriguez L L Barrera J D C | 1999 | The Veterinary Journal1999，157，： | 1 |
| 17 | Synthesis and RGD peptide modification of a new biodegradable copolymer: poly(lactic acid-co-lysine)显示文摘 | Barrera D A Zylstra E Lansbury P T | 1993 | J Am Chem Soc1993，115，11： | 1 |
| 18 | Macrophage and T lymphocyte apoptosis during experimental pulmonary, tuberculosis: their relationship to mycobacterial virulence 显示文摘 | RIOS BARRERA VICTOR A CAMPOS PENA V AGUILAR LE- ON D | 2006 | Eur J Immunol2006，36，2： | 1 |
| 19 | Carotid ultrasound ex- amination as an aging and disability marker 显示文摘 | Barrera G Bunout D de la Maza MP | 2014 | Geriatr Gerontol Int2014，14，3： | 1 |
| 20 | Risk factors for drug - resistant bloodstream infections in patients with systemic lupus erythematosus显示文摘 | Barrera - Vargas A Gomez - Martin D Merayo - ChalicoJ | 2014 | J Rheumatol2014，41，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员