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	题名	作者	年代	出处	被引量
1	Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response.	Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu	2016	World Journal of Gastrointestinal Oncology2016，8，9：	3
2	Increased serum IGF-I during pregnancy is associated with progression of diabetic retinopathy 显示文摘	Lauszus FF Klebe JG Bek T	2003	Diabetes2003，52，3：	1
3	Screening and prevention of diabetic blindness 显示文摘	Stefansson E Bek T Porta M	2000	Acta Ophthalmol Scand2000，78，：	1
4	Pathogenicity of Helicobacter pylori infection 显示文摘	Radosz-Komoniewska H Bek T Jozwiak J	2005	Clin Microbiol Infect2005，11，：	1
5	Immunohistochemical characterization of retinal glial cell changes in areas of vascular occlusion secondary to diabetic retinopathy显示文摘	Bek T	1997	Acta Ophthalmol Scand1997，75，4：	1
6	Visual prognosis after panretinal photocoagulation for proliferative diabetic retinopathy显示文摘	Bek T Erlandsen M	2006	Acta Ophthalmol Scand2006，84，1：	1
7	Prospective,multicentre,randomised evaluation of the safety and efficacy of five dosing regimens of viscosupplementation with hylan G-F20 in patients with symptomatic tibio-femoral osteoarthritis:a pilot study显示文摘	Conrozier T Jerosch J Beks P		Archives of Orthopaedic and Trauma Surgery0，，：	1
8	Transposition of the cephalic vein facil itated by an osseous subclavicular passage显示文摘	Burke GA Bek iroglu F Martin T J		0，，08：	1
9	Macular edema reflects generalized vascular hyperpermeability in type 2 diabetic patients with retinopathy显示文摘	Knudsen ST Bek T Poulsen PL	2002	Diabetes Care2002，25，5：	1
10	Identi- fication of independent risk factors for the development of diabetic retinopathy requiring treatment 显示文摘	MEHLSEN J ERLANDSEN M POULSEN PL BEK T	2011	Acta Ophthal- mol2011，89，6：	1
11	Lack of correlation between short-term dynamics of diabetic retinopathy lesions and the arterial blood pressure显示文摘	Bek T	2010	Graefes Arch Clin Exp Ophthalmol2010，3，：	1
12	Corneal versus scleral tunnel incison in cataract surgery: a randomized study显示文摘	Olsen T Dam-Johansen M Bek T	1997	J Cataract Refract Surg1997，23，3：	1
13	Low protein Z levels in children with nephrotic syndrome显示文摘	Ozkaya O Bek K Fisqin T	2006	Pediatr Nephrol2006，21，8：	1
14	Increased serum IGF-1 during pregnancy is associated with progression of diabetic retinopathy 显示文摘	Lauszus FF Klebe JG Bek T	2003	Diabetes2003，52，3：	1
15	24-h ambulatory blood pressure and retinopathy in normoalbumi-nuric IDDM patients显示文摘	Poulsen PL Bek T Ebbehej E	1998	Diabetologia1998，41，1：	1
16	Increased serum IGF - Ⅰ during pregnancy is associated with progression of diabetes显示文摘	Lauszus FF Klebe JG Bek T	2003	Diabetes2003，5，2：	1
17	Increased serum IGF-I during pregnancy is associated with progression of diabetic retinopathy显示文摘	Lauszus FF Klebe JG Bek T	2003	Diabetes2003，52，：	1
18	Corneal versus scleral tunnel incision in cataract surgery:a randomized study显示文摘	Olsen T Dam-Johansen M Bek T	1997	Cataract Refract Surg1997，25，3：	1
19	A retrospective drug utilization evaluation of vancomyein usage in paediatric patients显示文摘	HING W C BEK S J LIN R T	2004	J Clin Pharm Ther2004，29，4：	1
20	RAGE-mediated MAPK activation by food-derived AGE and non-AGE products显示文摘	Zill H Bek S Hofmann T	2003	Biochem Biophys Res Commun2003，300，2：	1

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