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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Urocortin,a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor显示文摘 | Vaughan J Donaldson C Bittencourt J | 1995 | Nature1995，378，6554： | 2 |
| 3 | Outcomes after coronary computed tomography angiography in the emergency department: a systematic review and meta- analysis of randomized, controlled trials 显示文摘 | Hulten E Pickett C Bittencourt MS | 2013 | J Am Coll Cardiol2013，61，8： | 1 |
| 4 | Assessing autonomic function in hypertrophic cardiomyopathy显示文摘 | Bittencourt MI Benchimol-Barbosa PR Drumond Neto C | 2005 | Arq Bras Cardiol2005，85，6： | 1 |
| 5 | WO3 films modified with functionalised multi-wall carbon nanotubes: Morphological, compositional and gas response studies显示文摘 | Bittencourt C Felten A Espinosa E H | 2006 | Sensors and Actuators B2006，115，1： | 1 |
| 6 | Compatibility of the fungus Metarhizium anisopliae and deltamethfin to control a resistant strain of Boophilus microplus tick显示文摘 | Bahiense T C Femandes E K Bittencourt V R | 2006 | Veterinary Parasitology2006，141，： | 1 |
| 7 | Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse显示文摘 | Van Pett K Viau V Bittencourt J C | 2000 | J Comp Neurol2000，428，2： | 1 |
| 8 | Replacement of Asymmetric Synaptic Profiles in the Molecular Layer of Dentate Gy- ms Following Cycloheximide in the Pilocarpine Model in Rats显示文摘 | Bittencourt S Covolan L Hamani C | 2015 | Front Psychiatry2015，17，6： | 1 |
| 9 | Infective dermatitis associated with HTLV-I mimics common eczemas in children and may be a prelude to severe systemic diseases 显示文摘 | Hlela C Bittencourt A | 2014 | Dermatol Clin2014，32，2： | 1 |
| 10 | Outcomes after coro- nary computed tomography angiography in the emergency depart-ment: a systematic review and meta - analysis of randomized, con- trolled triMs显示文摘 | Hulten E Pickett C Bittencourt MS | 2013 | J Am Coll Cardiol2013，61，8： | 1 |
| 11 | Urocortin, a mammalian neuropeptide related to fish urotensin I and to CRF 显示文摘 | Vaughan J Donaldson C Bittencourt J | 1995 | Nature1995，378，6554： | 1 |
| 12 | LC determination of enrofloxacin 显示文摘 | Souza M J Bittencourt C F Morsch L M | 2002 | J Pharma Biomed Anal2002，28，： | 1 |
| 13 | Microbiological assay for enrofloxacin injection 显示文摘 | Souza M J Bittencourt C F Paulo D A | 2004 | Int J Pharma2004，271，： | 1 |
| 14 | Diffusion-weighted magnetic resonance imaging in the upper abdomen: technical is- sues and clinical applications显示文摘 | Bittencourt L K Matos C Coutinho A C Jr | 2011 | Magn Reson Imaging Clin N Am2011，19，1： | 1 |
| 15 | Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor 显示文摘 | VAUGHAN J DONALDSON C BITTENCOURT J | 1995 | Nature1995，378，6554： | 1 |
| 16 | Compatibility of the fungus Metarhizium anisopliae and deltamethrin to control a resistant strain of Boophilus microplus tick显示文摘 | Bahiense T C Fernandes E K Bittencourt V R | 2006 | Veterinary Parasitology2006，141，34： | 1 |
| 17 | Association of classical risk factors and coronary artery disease in type 2diabetic patients submitted to coronary angiography显示文摘 | BITTENCOURT C PIVETA V M OLIVEIRA C S | 2014 | Diabetol Metab Syndr2014，6，： | 1 |
| 18 | Diffusion-weightedmagnetic resonance imaging in the upper abdomen : technical is-sues and clinical applications 显示文摘 | Bittencourt L K Matos C Coutinho AC Jr | 2011 | Magn Reson Imaging Clin NAm2011，19，1： | 1 |
| 19 | A novel approach for magnesia hydrationassessment in refractory castables显示文摘 | Salomao R Bittencourt L R M Pandolfelli V C | 2007 | Ceramics International2007，33，5： | 1 |
| 20 | Selection of binders for in-situ spinel refraetory castables显示文摘 | Braulio M A L Bittencourt I R M Pandolfelli V C | 2009 | Journal of the European Ceramic Society2009，29，： | 1 |
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