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| 1 | Prediction of median survival time in sepsis patients by the SOFA score combined with different predictors显示文摘Background:Sepsis is the leading cause of intensive care unit(ICU)admission.The purpose of this study was to explore the prognostic value of the Sequential Organ Failure Assessment(SOFA)score,the Acute Physiological and Chronic Health Evaluation Ⅱ(APACHE Ⅱ)score,and procalcitonin(PCT),albumin(ALB),and lactate(LAC)levels in patients with sepsis.Methods:Consecutive adult patients with suspected or documented sepsis at ICU admission were recruited.Their basic vital signs and related auxiliary examinations to determine their PCT and ALB levels and APACHE Ⅱ score were recorded at ICU admission,and their LAC levels and SOFA scores were recorded for one week after admission.The influence of these variables on hospital mortality was evaluated.Logistic regression was used to derive the Sepsis Hospital Mortality Score(SHMS),a prediction equation describing the relationship between predictors and hospital mortality.The median survival time was calculated by the Kaplan–Meier method.In the validation group,the kappa value was calculated to evaluate the stability of the derived formula.Results:This study included 894 sepsis patients admitted to 18 ICUs in 16 tertiary hospitals.Patients were randomly assigned to an experimental group(626 cases)and validation group(258 cases).In addition,a nonsurvival group(248 patients)of the experimental group was established according to the outcome at the time of discharge.The hospital mortality rate in the experimental group was 39.6%(248/626).Univariate and multivariate regression analyses revealed that the APACHE Ⅱ score(odds ratio[OR]=1.178),△SOFA(OR=1.186),△LAC(OR=1.157),and SOFA mean score(OR=1.086)were independently associated with hospital mortality.The SHMS was calculated as logit(p)=4.715–(0.164×APACHE Ⅱ)–(0.171×△SOFA)–(0.145×△LAC)–(0.082×SOFA mean).A receiver operating characteristic curve was constructed to further investigate the accuracy of the SHMS,with an area under the curve of 0.851(95%confidence interval[CI]0.821–0.882;p<0.001)for hospital mortality.In the low-risk group and high-risk groups,the corresponding median survival times were 15 days and 11 days,respectively.Conclusion:The APACHE Ⅱ score,△SOFA,△LAC and SOFA mean score were independently associated with hospital mortality in sepsis patients and accurately predicted the hospital mortality rate and median survival time.Data on the median survival time in sepsis patients could be provided to clinicians to assist in the rational use of limited medical resources by facilitating prudent resource allocation.Trial registration:ChiCTR-ECH-13003934,retrospectively registered on August 03,2013. | Wen Li Meiping Wang Bo Zhu Yibing Zhu Xiuming Xi | 2020 | Burns & Trauma2020，8，1： | 7 |
| 2 | An investigation ofthe thermal degradation of melamine phosphonite by XPS and thermalanalysis techniques显示文摘 | FENG Daming ZHOU Zhengmao BO Meiping | 1995 | Polymer Degradation and Stability1995，50，1： | 1 |
| 3 | Monomeric C-reactive protein alters fibrin clot properties on endothelial cells显示文摘 | Rong Li Meiping Ren Mao Luo Ni Chen Zhuo Zhang Bo Luo Jianbo Wu | 2012 | Thrombosis Research2012，，5： | 1 |
| 4 | Removing nitrogen and phosphorus from simulated wastewater using algal biofilm technique显示文摘Algal biofilmtechnology is a new and advanced wastewater treatment method.Experimental study on removing nitrogen and phosphorus from simulated wastewater using algal biofilm under the continuous light of 3500 Lux in the batch and continuous systems was carried out in this paper to assess the performance of algal biofilm in removing nutrients.The results showed that the effect of removing nitrogen and phosphorus by algal biofilm was remarkable in the batch system.The removal efficiencies of total phosphorus(TP),total nitrogen(TN),ammonianitrogen(NH_(3)-N),and chemical oxygen demand(COD)reached 98.17%,86.58%,91.88%,and 97.11%,respectively.In the continuous system,hydraulic retention time(HRT)of 4 days was adopted;the effects of removing TP,TN,NH_(3)-N,and COD by algal biofilm were very stable.During a run of 24 days,the removal efficiencies of TP,TN,NH_(3)-N,and COD reached 95.38%,83.93%,82.38%,and 92.31%,respectively.This study demonstrates the feasibility of removing nitrogen and phosphorus from simulated wastewater using algal biofilm. | Qun WEI Zhiquan HU Genbao LI Bo XIAO Hao SUN Meiping TAO | 2008 | Frontiers of Environmental Science & Engineering2008，2，4： | 0 |
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