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| 1 | Human papillomavirus in esophageal squamous cell carcinoma in Colombia and Chile显示文摘AIM: To examine the presence of human papillomavirus (HPV) in esophageal squamous cell carcinoma (ESCC) specimens collected from Colombia and Chile located in the northern and southern ends of the continent, respectively. METHODS: We examined 47 and 26 formalin-fixed and paraffin-embedded ESCC specimens from Colombia and Chile, respectively. HPV was detected using GP5+/GP6+ primer pair for PCR, and confirmed by Southern blot analysis. Sequencing analysis of L1 region fragment was used to identify HPV genotype. In addition, P16INK4A protein immunostaining of all the specimens was conducted. RESULTS: HPV was detected in 21 ESCC specimens (29%). Sequencing analysis of L1 region fragment identified HPV-16 genome in 6 Colombian cases(13%) and in 5 Chilean cases (19%). HPV-18 was detected in 10 cases (21%) in Colombia but not in any Chilean case. Since Chilean ESCC cases had a higher prevalence of HPV-16 (without statistical significance), but a significantly lower prevalence of HPV-18 than in Colombian cases (P = 0.011) even though the two countries have similar ESCC incidence rates, the frequency of HPV-related ESCC may not be strongly affected by risk factors affecting the incidence of ESCC. HPV-16 genome was more frequently detected in p16 positive carcinomas, although the difference was not statistically significant. HPV-18 detection rate did not show any association with p16 expression. Well-differentiated tumors tended to have either HPV-16 or HPV-18 but the association was not statistically significant. HPV genotypes other than HPV-16 or 18 were not detected in either country. CONCLUSION: HPV-16 and HPV-18 genotypes can be found in ESCC specimens collected from two South American countries. Further studies on the relationship between HPV-16 presence and p16 expression in ESCC would aid understanding of the mechanism underlying the presence of HPV in ESCC. | Andres Castillo Francisco Aguayo Chihaya Koriyama Miyerlandi Torres Edwin Carrascal Alejandro Corvalan Juan P Roblero Cecilia Naquira Mariana Palma Claudia Backhouse Jorge Argandona Tetsuhiko Itoh Karem Shuyama Yoshito Eizuru Suminori Akiba | 2006 | World Journal of Gastroenterology2006，12，38： | 11 |
| 2 | Effect of stripe rust on the yield response of wheat to nitrogen显示文摘Nitrogen(N) is the most important fertiliser element determining the productivity of wheat.N nutrition is known to affect the level of stripe rust infection, with higher N associated with increased disease severity. Stripe rust, caused by Puccinia striiformis f. sp. tritici, is a major yield-limiting disease of wheat in Australia. This paper describes experiments designed to investigate the agronomic response to the interaction of various levels of N application and stripe rust severity in wheat varieties differing in response. Experimental plots were established in crop seasons 2006 and 2007 on the Liverpool Plains of northern NSW, Australia.Yield, biomass, grain protein content(GPC) and harvest index(HI) data were recorded.Increased rates of N increased the severity of stripe rust during grain filling. N application also increased yield and GPC in all varieties in both years. Stripe rust reduced the yield of the rust-susceptible wheat varieties, and GPC and proportion of added N recovered in the grain were also reduced in one year but not the other. It was evident from our experiment that stripe rust caused yield loss accompanied by either no change or reduction in GPC, indicating that the total amount of N entering the grain was reduced by stripe rust. The effects of stripe rust on N yield are most likely associated with reduced uptake of N during grain filling. | Rakhesh Devadas Steven Simpfendorfer David Backhouse David W.Lamb | 2014 | The Crop Journal2014，2，4： | 3 |
| 3 | Temperature effectson the relative abundance of Fusariumspecies in a model plant-soil ecosystem显示文摘 | Saremi H Burgess L W Backhouse D | 1999 | Soil Biology and Biochemistry1999，31，7： | 1 |
| 4 | Postponement: a review and an inte- grated framework显示文摘 | Yang B Burns N D Backhouse C J | 2004 | International Journal of Operations and Production Management2004，24，5： | 1 |
| 5 | Carbon-fibre non-crimp fabric laminates for cost-effective damage-tolerant structures显示文摘 | G.A Bibo P.J Hogg R Backhouse A Mills | 1998 | Composites Science and Technology1998，，1： | 1 |
| 6 | Gender differences in VLDL1 and VLDL2 triglyceride kinetics and fatty acid kinetics in obese postmenopausal women and obese men显示文摘 | Sarac I Backhouse K Shojaee-Moradie F | 2012 | J Clin Endocrinol Metab2012，97，7： | 1 |
| 7 | Effects of the glycemic index of breakfast on metabolic responses to brisk walking in females显示文摘 | Backhouse SH Williams C Stevenson E | 2007 | Eur J Clin Nutr2007，61，5： | 1 |
| 8 | Surface soil moisture and stubble management practice effects on the progress of infection of wheat by Fusarium pseudograminearum 显示文摘 | Swan L J Backhouse D Burgess L W | 2000 | Australian Journal of Experimental Agriculture2000，40，： | 1 |
| 9 | An empirical investigationinto the barriers to postponement 显示文摘 | Yang B Burns N D Backhouse C J | 2005 | Intemational Journal ofProduction Research2005，43，5： | 1 |
| 10 | Flexible induction dose regimen for warfarin and prediction of maintance dose显示文摘 | Dolben J Thomas P Backhouse G Bentley DP Campbell IA | 1984 | Br Med J1984，288，2： | 1 |
| 11 | Treponema pallidum western blot: comparison with the FTA-ABS test as a confirmatory test for syphilis显示文摘 | Backhouse JL Nesteroff SI | 2001 | Diagn Microbiol Infect Dis2001，39，1： | 1 |
| 12 | Development and structure of infection cushions of Botrytis cinerea 显示文摘 | Backhouse D Willetts H J | 1987 | Transactions of British Mycological Society1987，89，1： | 1 |
| 13 | Management of uncertaintythrough postponement 显示文摘 | Yang B Bums N D Backhouse C J | 2004 | Intemational Journal of ProductionResearch2004，42，6： | 1 |
| 14 | U-238 decay chain:Resolution of observed anomalies in the measured secular equilibrium between Th-234 and daughter Pa-234m显示文摘 | ADSLEY I BACKHOUSE J S NICHOLS A L | 1998 | Applied Radiation and Isotopes1998，49，911： | 1 |
| 15 | Anti-inflammatory and antipyretic effects of boldine 显示文摘 | Backhouse N Delporte C Givernau M | 1994 | Agents Actions1994，42，： | 1 |
| 16 | Management of uncertainty through postponement 显示文摘 | Yang B Burns N D Backhouse C J | 2004 | International Journal of Production Research2004，42，6： | 1 |
| 17 | Sur- vey of Fusarium species associated with crown rot of wheat and barley in eastern Australia显示文摘 | Backhouse D Abubakar A A Burgess L W | 2004 | Australasian Plant Pathology2004，33，2： | 1 |
| 18 | Influence of periodic vs continuous daily bright light exposure on development of experimental myopia in the chick显示文摘 | Backhouse S Collins AV Phillips JR | 2013 | Ophthalmic Physiol 0pt2013，33，5： | 1 |
| 19 | Effect of retinal image defocus on the thickness of the human choroid 显示文摘 | Chiang ST Phillips JR Backhouse S | 2015 | Ophthalmic Physiol Opt2015，35，4： | 1 |
| 20 | Ro- bust Visual Object Tracking Using Multi-Mode Anisotropic Mean Shift and Particle Filters显示文摘 | Khan Zulfiqar Hasan Gu Irene Yu-Hua Backhouse A G | 2011 | IEEE Transactions on Cir- cuits and Systems for Video Ttechnology2011，21，1： | 1 |
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