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| 1 | Rubber band ligation for 750 cases of symptomatic hemorrhoids out of 2200 cases显示文摘AIM: To study the results for the treatment of symptomatic hemorrhoids using rubber band ligation (RBL) method. METHODS: A retrospective study for 750 patients who came to the colorectal unit from June, 1998 to September, 2006, data was retrieved from archived fi les. RBL was performed using the Mc Gown applicator on an outpatient basis. The patients were asked to return to out-patient clinic for follow up at 2 wk, 1 mo, 6 mo and through telephone call every 6 mo for 2 years). RESULTS: After RBL, 696 patients (92.8%) were cured with no difference in outcome for second or third degree hemorrhoids (P = 0.31). Symptomatic recurrence was detected in 11.04% after 2 years. A total of 52 patients (6.93%) had 77 complications from RBL which required no hospitalization. Complications were pain, rectal bleeding and vaso-vagal symptoms(4.13%, 4.13% and 1.33% of patients, respectively). At 1 mo there were a significant improvement in mean SF-36 scores over baseline in five items, while after 2 years there were improvement in all items over baseline, but not significant. No significant manometeric changes after band ligation. CONCLUSION: RBL is a simple, safe and effective method for treating symptomatic second and third degree hemorrhoids as an out patient procedure with signifi cant improvement in quality of life. RBL doesn't alter ano-rectal functions. | Ayman M El Nakeeb Amir A Fikry Waleed H Omar Elyamani M Fouda Tito A El Metwally Hosam E Ghazy Sabry A Badr Mohmed Y Abu Elkhar Salih M Elawady Hisham H Abd Elmoniam Waiel W Khafagy Mosaad M Morshed Ramadan E El Lithy Mohamed E Farid | 2008 | World Journal of Gastroenterology2008，14，42： | 24 |
| 2 | Hepatitis B genotypes: Relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia显示文摘AIM: To identify the most common hepatitis B virus (HBV) genotype in Saudi Arabia, and correlate the prevailing genotypes with the clinical outcome of patients. METHODS: Patients were consecutively recruited from the hepatology clinics of two tertiary care referral cen- ters. Patients were categorized into 4 different groups: group 1, patients with hepatitis B and normal liver en- zymes; group 2, patients with hepatitis B and abnormal liver enzymes but without cirrhosis; group 3, patients with hepatitis B and liver cirrhosis; group 4, patients with hepatitis B and hepatocellular carcinoma. All patients had a positive hepatitis B surface antigen (HBsAg). Ge- notyping of HBV was performed by nested PCR-mediated amplification of the target sequence and hybridization with sequence-specific oligonucleotides. RESULTS: Seventy patients were enrolled in this study. They were predominantly male (72.9%) in their mid- forty’s (mean age 47 years). Forty-nine (70%) patients were hepatitis B envelope antigen (HBeAg) negative. The majority of patients (64%) acquired HBV through unknown risk factors. Hepatitis B genotyping revealed that 57 patients (81.4%) were genotype D, 1 patient (1.4%) had genotype A, 1 patient (1.4%) had geno- type C, and 4 patients (5.7%) had genotype E, while 7 patients (10%) had mixed genotype (4 patients ADG, 1 patient DE, 1 patient DF, and 1 patient ADFG). Based on univariate analysis of genotype D patients, significant predictors of advanced liver disease were age, gender, aspartate transaminase, alanine transaminase, albumin,bilirubin, and alkaline phosphatase (all P < 0.001). In multivariate analysis decreased hemoglobin (r = -0.05; 95% CI: -0.08 to -0.03; P = 0.001) and albumin levels (r = -0.004; 95% CI: -0.007 to -0.001; P = 0.002) were highly significant predictors of advanced liver disease. In patients with HBV genotype D, HBeAg negativity was found to increase across advancing stages of liver dis- ease (P = 0.024). CONCLUSION: This study highlights that the vast ma- jority of Saudi patients with chronic hepatitis B have genotype D. No correlation could be observed between the different genotypes and epidemiological or clinical factors. The relationship between genotype D and HBeAg status in terms of disease severity needs to be further elucidated in larger longitudinal studies. | Ayman A Abdo Badr M Al-Jarallah Faisal M Sanai Ahmad S Hersi Khalid Al-Swat Nahla A Azzam Manal Al-Dukhayil Amira Al-Maarik Faleh Z Al-Faleh | 2006 | World Journal of Gastroenterology2006，12，43： | 7 |
| 3 | Role of relevant immune-modulators and cytokines in hepatocellular carcinoma and premalignant hepatic lesions显示文摘AIM To assess the levels of different immune modulators in patients with hepatocellular carcinoma(HCC),in relation to other hepatic diseases.METHODS Eighty-eight patients were included in the current study and represented patients with HCC(20),liver cirrhosis(28) and chronic hepatitis(CH;25),and normal controls(NC;15).Peripheral blood was isolated for immunophenotyping of active myeloid dendritic cells(m DCs;CD1 c and CD40),mature inactive myeloid cells(CD1 c and HLA),active plasmacytoid cells(p DCs;CD303 and CD40),mature inactive p DCs(CD30 and HLA),active natural killer(NK) cells(CD56 and CD161),active NK cells(CD56 and CD314) and inactive NK cells(CD56 and CD158) was done by flow cytometry.Serum levels of interleukin(IL)-2,IL-10,IL-12,IL-1β,interferon(IFN)-α,IFN-γ and tumor necrosis factor(TNF)-αR2 were assessed by ELISA.RESULTS Active m DCs(CD1 C+/CD40+) and inactive m DCs(CD1 c+/HLA+) were significantly decreased in HCC patients in relation to NC(P < 0.001).CD40+ expression on active p DCs was decreased in HCC patients(P < 0.001),and its level was not significantly changed among other groups.Inactive p DCs(CD303+/HLA+),inactive NKs(CD56+/CD158+) and active NKs(CD56+/CD161+) were not statistically changed among the four groups studied;however,the latter was increased in CH(P < 0.05).NKG2 D was statistically decreased in HCC,CH and cirrhosis(P < 0.001),and it was not expressed in 63%(12/20) of HCC patients.There was significant decrease of IL-2,IFN-α and IFN-γ(P < 0.001),and a significant increase in IL-10,IL-1β,and TNF-αR2(P <0.01,P < 0.001 and P < 0.001;respectively) in HCC patients.There was inverted correlation between IL-12 and IL-1β in HCC(r =-0.565,P < 0.01),with a strong correlation between p DCs(CD303+/CD40+) and NKs(CD56+/CD161+;r = 0.512,P < 0.05) as well as inactive m DCs(CD1 c+/HLA+) and inactive NK cells(CD56+/CD158+;r = 0.945,P < 0.001).CONCLUSION NKG2 D,CD40,IL-2 and IL-10 are important modulators in the development and progression of HCC. | Abdel-Rahman N Zekri Somaya El Deeb Abeer A Bahnassy Abeer M Badr Mona S Abdellateif Gamal Esmat Hosny Salama Marwa Mohanad Ahmed Esam El-dien Shimaa Rabah Assmaa Abd Elkader | 2018 | World Journal of Gastroenterology2018，24，11： | 6 |
| 4 | Endoscopic management of Dieulafoy's lesion using Isoamyl-2-cyanoacrylate显示文摘Dieulafoy's lesion (DL) is a rare but important cause of obscure gastrointestinal bleeding that may be over-looked during diagnostic endoscopy. Mortality rates are similar to those of other causes for gastrointestinal bleeding. Diagnosis by upper endoscopy is the modal-ity of choice during acute bleeding. In the absence of active bleeding, the lesion resembles a raised nipple or visible vessel. There are no guidelines regarding effective selective therapy for DL, when diagnosed, en-doscopist experience is the major determinant of the treatment strategy. Following our strategy, an expert endoscopist with a skilled assistant should have a high rate of successful DL diagnosis when an obscured gas-trointestinal lesion is suspected. Cyanoacryltes com-pounds have been used successfully in management of Gastric varices and DLs. To our knowledge, there have been no previous reports regarding use of isoamyl-2-cyanoacrylate (AMCRYLATE ; Concord Drugs Ltd.,Hyderabad, India) as an effective therapy for gastric DL without serious complications. In our case study, Isoamyl-2-cyanoacrylate (AMCRYLATE) was effective and safe for treating DL. Surgical wedge resection of the lesion should be considered as a therapeutic option if endoscopic therapy fails. | Abd Elrazek M Aly Abd Elrazek Nakamura Yoko Moriguchi Hiroki Mohamed Afify Mohamed Asar Badr Ismael Magdy Salah | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，8： | 3 |
| 5 | Plasma D-dimer level in early and late-onset neonatal sepsis显示文摘BACKGROUND Neonatal sepsis is a life-threatening disease.Early diagnosis is essential,but no single marker of infection has been identified.Sepsis activates a coagulation cascade with simultaneous production of the D-dimers due to lysis of fibrin.Ddimer test reflects the activation of the coagulation system.AIM To assess the D-dimer plasma level,elaborating its clinicopathological value in neonates with early-onset and late-onset neonatal sepsis.METHODS The study was a prospective cross-sectional study that included ninety neonates;divided into three groups:Group I:Early-onset sepsis(EOS);Group II:Late-onset sepsis(LOS);and GroupⅢ:Control group.We diagnosed neonatal sepsis according to our protocol.C-reactive protein(CRP)and D-dimer assays were compared between EOS and LOS and correlated to the causative microbiological agents.RESULTS D-dimer was significantly higher in septic groups with a considerably higher number of cases with positive D-dimer.Neonates with LOS had substantially higher levels of D-dimer than EOS,with no significant differences in CRP.Neonates with LOS had a significantly longer hospitalization duration and higher gram-negative bacteriemia and mortality rates than EOS(P<0.01).Gramnegative bacteria have the highest D-dimer levels(Acinetobacter,Klebsiella,and Pseudomonas)and CRP(Serratia,Klebsiella,and Pseudomonas);while gram-positive sepsis was associated with relatively lower levels.D-dimer had a significant negative correlation with hemoglobin level and platelet count;and a significant positive correlation with CRP,hospitalization duration,and mortality rates.The best-suggested cut-off point for D-dimer in neonatal sepsis was 0.75 mg/L,giving a sensitivity of 72.7%and specificity of 86.7%.The D-dimer assay has specificity and sensitivity comparable to CRP in the current study.CONCLUSION The current study revealed a significant diagnostic value for D-dimer in neonatal sepsis.D-dimer can be used as an adjunct to other sepsis markers to increase the sensitivity and specificity of diagnosing neonatal sepsis. | Mohammed Al-Biltagi Ehab M Hantash Mohammed Ramadan El-Shanshory Enayat Aly Badr Mohamed Zahra Manar Hany Anwar | 2022 | World Journal of Critical Care Medicine2022，11，3： | 2 |
| 6 | A comparative study on the starting methods of three phase wound- rotor induction motor-Part I显示文摘 | Hamouda R M Alolah A I Badr M A | 1999 | IEEE Trans on Energy Conversion1999，14，4： | 1 |
| 7 | Characterisitcs of flow field and water concentration in a horizontal dedleg 显示文摘 | Habib M A Badr H M Said S A M | 2005 | Heal Mass Transfer2005，41，： | 1 |
| 8 | CW Nd:YAG laser cutting of ultra low carbon steel thin sheets using 02 assist gas 显示文摘 | H G Salem M S Mansour Y Badr | 2008 | Journal of Materials Processing Technology2008，196，1： | 1 |
| 9 | Continuous acetone-ethanol-butanol fermentation by immobilized cells of Clostridium acetobutylicum 显示文摘 | Badr H R Toledo R Hamdy M K | 2001 | Biomass and Bioenergy2001，20，2： | 1 |
| 10 | Endoscopically assisted minimally invasive microvascular decompression of hemifacial spasm 显示文摘 | Badr E1 Dine M El Garem H F Talaat A M | 2002 | Otol Neurotol2002，23，2： | 1 |
| 11 | Effect of geometry on flow fiehl and oil/water separation in vertical deadlegs 显示文摘 | Habib M A Said S A M Badr H M | 2005 | International Journal for Numerical Meth- ods in Heat & Fluid Flow2005，15，4： | 1 |
| 12 | Lower pole midsize (1-2 cm) calyeeal stones: outcome analysis of 56 cases显示文摘 | Aboutaleh H E1-Shazly M Badr Eldin M | 2012 | Urollnt2012，89，3： | 1 |
| 13 | Laminar natural convection from an elliptic tube with different orientations显示文摘 | | 1997 | Journal of Heat Transfer1997，119，： | 1 |
| 14 | Combined convection from an isothermal horizontal rod buried in a porous medium显示文摘 | Badr H M | 1988 | Int J Heat Mass Transfer1988，31，12： | 1 |
| 15 | Role of Perooxisoroe Proliferatoractivated Receptors in Inflammation Control 显示文摘 | Youssef J Badr M | 2004 | Joumalof biomedicine & biotechnology2004，，3： | 1 |
| 16 | Optical ,structural and optoelec- tronic properties of pulsed laser deposition PbS thin film 显示文摘 | Atwa D M M Azzouz I M Badr Y | 2011 | Applied Physics B2011，103，1： | 1 |
| 17 | Biosynthesis of gold nanoparticles using Pseudomonas aeruginosa 显示文摘 | HUSSEINY M I EL-AZIZ M A BADR Y | 2007 | Spectrochimiea Aeta Part A: Molecular and Biomoleeular Spectroscopy2007，67，3： | 1 |
| 18 | Prospective evaluation of the prevalence of gastric Helicobacter pylofi infection in patients with GERD, Barrett's esophagus, Barrett's dysplasia, and Barrett's adenocarcinoma显示文摘 | Weston AP Badr AS Topalovski M | 2000 | Am J Gastroenterol2000，95，2： | 1 |
| 19 | Image classification and retrieval using optimized pulse-coupled neural network 显示文摘 | MOHAMMED M M BADR A ABDELHALIM M B | 2015 | Expert Systems with Applications2015，42，49： | 1 |
| 20 | Water-repellent ZnO nanowires films obtained by octadecylsilane self-assembled monolayers 显示文摘 | Badre C Pauporte T Turmine M | 2008 | Physica E2008，40，7： | 1 |
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