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| 1 | Endoscopic retrograde cholangiopancreatography in periampullary diverticulum: The challenge of cannulation显示文摘Periampullary diverticulum(PAD) is duodenal outpunching defined as herniation of the mucosa or submucosa that occurs via a defect in the muscle layer within an area of 2 to 3 cm around the papilla. Although PAD isusually asymptomatic and discovered incidentally during endoscopic retrograde cholangiopancreatography(ERCP), it is associated with different pathological conditions such as common bile duct obstruction, pancreatitis, perforation, bleeding, and rarely carcinoma. ERCP has a low rate of success in patients with PAD,suggesting that this condition may complicate the technical application of the ERCP procedure. Moreover, cannulation of PAD can be challenging, time consuming, and require the higher level of skill of more experienced endoscopists. A large portion of the failures of cannulation in patients with PAD can be attributed to inability of the endoscopist to detect the papilla. In cases where the papilla is identified but does not point in a suitable direction for cannulation, different techniques have been described. Endoscopists must be aware of papilla identification in the presence of PAD and of different cannulation techniques, including their technical feasibility and safety, to allow for an informed decision and ensure the best outcome. Herein, we review the literature on this practical topic and propose an algorithm to increase the success rate of biliary cannulation. | Ahmed Youssef Altonbary Monir Hussein Bahgat | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，6： | 11 |
| 2 | Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression显示文摘AIM: To evaluate the effect of resveratrol, alone and in combination with fenofibrate, on fructose-induced metabolic genes abnormalities in rats. METHODS: Giving a fructose-enriched diet(FED) to rats for 12 wk was used as a model for inducing hepatic dyslipidemia and insulin resistance. Adult male albino rats(150-200 g) were divided into a control group and a FED group which was subdivided into 4 groups, a control FED, fenofibrate(FENO)(100 mg/kg), resveratrol(RES)(70 mg/kg) and combined treatment( FENO + RES)( half the doses). A l l treatments were given orally from the 9th week till the end of experimental period. Body weight, oral glucose tolerance test(OGTT), liver index, glucose, insulin, insulin resistance(HOMA), serum and liver triglycerides(TGs), oxidative stress(liver MDA, GSH and SOD),serum AST, ALT, AST/ALT ratio and tumor necrosis factor-α(TNF-α) were measured. Additionally, hepatic gene expression of suppressor of cytokine signaling-3(SOCS-3), sterol regulatory element binding protein-1c(SREBP-1c), fatty acid synthase(FAS), malonyl Co A decarboxylase(MCD), transforming growth factor-β1(TGF-β1) and adipose tissue genes expression of leptin and adiponectin were investigated. Liver sections were taken for histopathological examination and steatosis area were determined.RESULTS: Rats fed FED showed damaged liver, impairment of glucose tolerance, insulin resistance, ox ida t ive s t re s s a nd dy s l ipide m ia. As fo r ge ne expression, there was a change in favor of dyslipidemia and nonalcoholic steatohepatitis(NASH) development. All treatment regimens showed some benefit in reversing the described deviations. Fructose caused deterioration in hepatic gene expression of SOCS-3, SREBP-1c, FAS, MDA and TGF-β1 and in adipose tissue gene expression of leptin and adiponectin. Fructose showed also an increase in body weight, insulin resistance(OGTT, HOMA), serum and liver TGs, hepatic MDA, serum AST, AST/ALT ratio and TNF-α compared to control. All treatments improved SOCS-3, FAS, MCD, TGF-β1 and leptin genes expression while only RES and FENO + RES groups showed an improvement in SREBP-1c expression. Adiponectin gene expression was improved only by RES. A decrease in body weight, HOMA, liver TGs, AST/ALT ratio and TNF-α were observed in all treatment groups. Liver index was increased in FENO and FENO + RES groups. Serum TGs was improved only by FENO treatment. Liver MDA was improved by RES and FENO + RES treatments. FENO + RES group showed an increase in liver GSH content.CONCLUSION: When resveratrol was given with half the dose of fenofibrate it improved NASH-related fructose-induced disturbances in gene expression similar to a full dose of fenofibrate. | Enas A Abd El-Haleim Ashraf K Bahgat Samira Saleh | 2016 | World Journal of Gastroenterology2016，22，10： | 5 |
| 3 | HepG2 cells support viral replication and gene expression of hepatitis C virus genotype 4 in vitro显示文摘瞄准:与丙肝的长期的复制建立一个房间文化系统病毒(HCV ) 染色体和病毒的抗原的表示在试管内。方法:HepG2 房间线被孵化与长期的丙肝从一个病人与浆液为它的危险性测试到 HCV。房间和上层清液在文化期间在各种各样的时间点被收获。文化上层清液为它感染天真的房间的能力被测试。存在减(反感觉) 在房间的核心和 E1 抗原的 RNA 海滨,和察觉被 RT-PCR 和免疫学的技术(流动血细胞计数和西方的污点) 分别地检验。结果:细胞内部的 HCV RNA 首先在 d 上被检测 3 在感染以后然后能一致地在至少三个月的一个时期上在房间和上层清液被检测。新鲜房间能从有教养的感染的房间感染上层清液。流动 cytometric 分析证明表面和在房子里使用的细胞内部的 HCV 抗原表示使 polyclonal 成为了抗体(反核心,和 anti-E1 ) 。西方的污点分析证明在分子量的产生免疫性的肽的簇的表示在一个月内在 31 和 45 kDa 之间延长了感染的房间的旧文化而这簇在 uninfected HepG2 房间是无法发现的。结论:HepG2 房间线产生 HCV 感染而且支持它的复制在试管内不仅。HCV 结构的蛋白质的表示能在感染的 HepG2 房间被检测。这些房间也能够流病毒的粒子进接着对 uninfected 房间变得传染的培养基。 | Mostafa K El-Awady Ashraf A Tabll Yasmine S El-Abd Mahmoud M Bahgat Hussein A Shoeb Samar S Youssef Noha G Bader El Din El-Rashdy M Redwan Maha El-Demellawy Moataza H Omran Wael T El-Garf Said A Goueli | 2006 | World Journal of Gastroenterology2006，12，30： | 2 |
| 4 | Energy and the Arab-Israeli conflict显示文摘 | Bahgat G | 2008 | Middle Eastern Studies2008，44，6： | 1 |
| 5 | A modified direct nitridation method for formation of nano-AIN whiskers 显示文摘 | RADWAN M BAHGAT M | 2007 | J Mater Process Technol2007，181，123： | 1 |
| 6 | Serodiagnosis of Schistosoma mansoni infections in an endemic area of Burkina Faso:performance of several immunological tests with different parasite antigens显示文摘 | Sorgho H Bahgat M Poda JN | 2005 | Acta Tropica2005，93，： | 1 |
| 7 | Egypt and Iran: ITie 30 - yearestrangement显示文摘 | Gawdat Bahgat | 2009 | Middle East Policy2009，，4： | 1 |
| 8 | Char-acterization of NS3 protease from an Egyptian HCVgenotype 4a isolate 显示文摘 | Bahgat MM Ibrahim AA Abd-Elshafy DN | 2009 | Arch Virol2009，154，10： | 1 |
| 9 | Energy partnership: Israel and the Persian Gulf显示文摘 | Bahgat G | 2005 | Energy Policy2005，33，5： | 1 |
| 10 | Maximum power point tracking controller for PV sys- tems using neural networks 显示文摘 | Bahgat ABG Helwa NH Ahmad GE El Shenawy ET | 2005 | Renew Energy2005，30，8： | 1 |
| 11 | Reduction investigation of WO 3 /NiO/Fe 2 O 3 and synthesis of nanocrystalline ternary W–Ni–Fe alloy显示文摘 | M. Bahgat Min-Kyu Paek Jong-Jin Pak | 2008 | Journal of Alloys and Compounds2008，，1： | 1 |
| 12 | A novel approach for synthesis of nanocrystalline c-LiAIO~ fi'om spent lithium-ion batter- ies显示文摘 | FOUAD O A FARGHALY F I BAHGAT M | 2007 | J Anal Appl Pyrol2007，78，： | 1 |
| 13 | Reduction kinetics and mechanisms of Ni Fe2O4with synthesis of nanocrystalline Fe-Ni alloy显示文摘 | Bahgat M Paek M K Pak J J | 2007 | Materials Transactions2007，48，12： | 1 |
| 14 | Maximum Power Point Tracking Controller for PV Systems Using Neural Networks显示文摘 | Helwa N H Ahmad G E | 2005 | Renew Energy2005，30，： | 1 |
| 15 | Trigeminal neuralgia inyoung adults 显示文摘 | Bahgat D Ray DK Raslan AM | 2011 | J Neurosurg2011，114，5： | 1 |
| 16 | Serodiagnosis of Schistosoma mansoni infections in an endemic area of Burkina Faso:performance of several immunological tests with different parasite antigens显示文摘 | Sorgho H Bahgat M Poda J N | 2005 | Acta Trop2005，93，2： | 1 |
| 17 | A novel approach for synthesis of nanocrystallineγ-LiAlO2 from spent lithium-ion batteries显示文摘 | FOUAD O A FARGHALY F I BAHGAT M | 2007 | J Anal Appl Pyrolysis2007，78，： | 1 |
| 18 | Ginkgo biloba extract ( EGb 761 ) normalizes hypertension in 2K, 1C hypertensive rats : Role of antioxidant mechanisms, ACE inhibiting activity and improvement of endothelial dysfunction 显示文摘 | Mansour SM Bahgat AK E1-Khatib AS | 2011 | Phytomedicine2011，18，89： | 1 |
| 19 | Physical properties of some rare earth tellurite glasses显示文摘 | BAHGAT A A SHAISHA E E SABTY A I J | 1987 | Mater Sci1987，22，： | 1 |
| 20 | Nanostructured Ni-AlN composite coatings显示文摘 | Abdel Aal A Bahgat M Radwan M | 2006 | Surface and Coatings Technology2006，201，6： | 1 |
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