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| 1 | Minimal hepatic encephalopathy matters in daily life显示文摘Minimal hepatic encephalopathy is a neuro-cognitive dysfunction which occurs in an epidemic proportion of cirrhotic patients,estimated as high as 80% of the population tested. It is characterized by a specific,complex cognitive dysfunction which is independent of sleep dysfunction or problems with overall intelligence. Although named 'minimal',minimal hepatic encephalopathy(MHE) can have a far-reaching impact on quality of life,ability to function in daily life and progression to overt hepatic encephalopathy. Importantly,MHE has a profound negative impact on the ability to drive a car and may be a significant factor behind motor vehicle accidents. A crucial aspect of the clinical care of MHE patients is their driving history,which is often ignored in routine care and can add a vital dimension to the overall disease assessment. Driving history should be an integral part of care in patients with MHE. The lack of specific signs and symptoms,the preserved communication skills and lack of insight make MHE a difficult condition to diagnose. Diagnostic strategies for MHE abound,but are usually limited by financial,normative or time constraints. Recent studies into the inhibitory control and critical flicker frequency tests are encouraging since these tests can increase the rates of MHE diagnosis without requiring a psychologist. Although testing for MHE and subsequent therapy is not standard of care at this time,it is important to consider this in cirrhotics in order to improve their ability to live their life to the fullest. | Jasmohan S Bajaj | 2008 | World Journal of Gastroenterology2008，14，23： | 30 |
| 2 | 肥胖患者的冠状动脉微血管功能障碍和心血管病风险显示文摘全世界有〉5亿的肥胖人群,其心血管病风险增加的病理生理机制是复杂的,并且可能涉及脂肪细胞相关因子的过量分泌,导致血管氧化应激增加,神经激素活性上调,以及低度全身炎症,可能导致交感神经系统激活增加,血管张力改变,冠状动脉微血管功能障碍(coronary microvascular dysfunction, CMD) 。 | Bajaj NS Osborne MT Gupta A Tavakkoli A Bravo PE Vita T Bibbo CF Hainer J Dorbala S Blankstein R Bhatt DL Di Carli MF Taqueti VR 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，9： | 11 |
| 3 | The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts显示文摘Heterogeneous nuclear ribonucleoprotein(hnRNP) C plays a key role in RNA processing but also exerts a dominant negative effect on responses to 1,25-dihydroxyvitamin D(1,25(OH)2D) by functioning as a vitamin D response element-binding protein(VDRE-BP). hnRNPC acts a tetramer of hnRNPC1(huC1) and hnRNPC2(huC2), and organization of these subunits is critical to in vivo nucleic acid-binding. Overexpression of either huC1 or huC2 in human osteoblasts is sufficient to confer VDRE-BP suppression of 1,25(OH)2D-mediated transcription. However, huC1 or huC2 alone did not suppress 1,25(OH)2D-induced transcription in mouse osteoblastic cells. By contrast, overexpression of huC1 and huC2 in combination or transfection with a bone-specific polycistronic vector using a ‘‘self-cleaving'' 2A peptide to co-express huC1/C2 suppressed1,25D-mediated induction of osteoblast target gene expression. Structural diversity of hnRNPC between human/NWPs and mouse/rat/rabbit/dog was investigated by analysis of sequence variations within the hnRNP CLZ domain. The predicted loss of distal helical function in hnRNPC from lower species provides an explanation for the altered interaction between huC1/C2 and their mouse counterparts. These data provide new evidence of a role for hnRNPC1/C2 in 1,25(OH)2D-driven gene expression, and further suggest that species-specific tetramerization is a crucial determinant of its actions as a regulator of VDR-directed transactivation. | Thomas S Lisse Kanagasabai Vadivel S Paul Bajaj Rui Zhou Rene F Chun Martin Hewison John S Adams | 2014 | Bone Research2014，2，2： | 2 |
| 4 | Evalualion of polyletrafluoroethylene suture for frontalis suspension as compared to polybutylate - coaled braided polyester 显示文摘 | Bajaj MS Sastry SS Ghose S | 2004 | Clin Experiment Opht hal mol2004，32，4： | 1 |
| 5 | Flexural fatigue strength of hybrid fibrous concrete beams显示文摘 | Singh S Singh A Bajaj V | 2012 | Construction Materials2012，165，2： | 1 |
| 6 | Plasma resist in concertration hepatic fat content,and hepatic and peripheral insulin resistance in pioglitazonetreated type diabetic patients显示文摘 | Bajaj M Suraamomkul S Hardies LJ | 2004 | Int J Obes Relat Metab Disord2004，28，6： | 1 |
| 7 | Gellan gum: fermentative production, downstream pro- cessing and apphcations 显示文摘 | BAJAJ I B SURVASE S A SAUDAGAR P S | 2007 | Food Technology and Bio- technology2007，45，4： | 1 |
| 8 | Interspecific hybridization between Vigna mungo and Vigna radiata through embryo culture 显示文摘 | Gosal S S Bajaj Y P S | 1983 | Euphytica1983，32，： | 1 |
| 9 | Flocculation properties of poly(γ-glutamic acid)produced from Bacillus subtilis isolate显示文摘 | BAJAJ I B SINGHAL R S | 2011 | Food Bioprocess Technol2011，4，5： | 1 |
| 10 | Improving admission temperature in extremely low birth weight infants: a hospital -based multi-intervention quality improvement proieet显示文摘 | Billimoria Z Chawla S Bajaj M | 2013 | J Perinat Med2013，41，4： | 1 |
| 11 | Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone treated type 2 diabetic palients显示文摘 | Bajaj M Suraamornkul S Piper P Hardies L J Glass L Cersosimo E | 2004 | J Clin Endocrinol Metab2004，89，： | 1 |
| 12 | Recent applications of microwaves in synthesis of bioactive heterocyclic compounds显示文摘 | Jindal R Bajaj S | 2008 | Curr Org Chem2008，12，10： | 1 |
| 13 | Plasma resistin concentration, hepatic fat contem, and hepatic and peripheral insulin resistance in pioglitazonetreated type II diabetic patients显示文摘 | Bajaj M Suraamornkul S Hardies L J Pratipanawatr T De- Fronzo R A | 2004 | Int J Obes Relat Metab Disord2004，28，： | 1 |
| 14 | p53 and related proteins in epithelial ovarian cancer显示文摘 | Sengupta P S Mcgown A T Bajaj V | 2000 | European Journal of cancer2000，36，： | 1 |
| 15 | Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients 显示文摘 | Bajaj M Suraamornkul S Piper P | 2004 | J Clin Endocrinol Metab2004，89，： | 1 |
| 16 | Advances in three dimensional reconstruction of the experimental spinal cord injury显示文摘 | Duerstock B S Bajaj C L Pascucci V | 2000 | Comput Med Imaging Graph2000，24，6： | 1 |
| 17 | Effica- cy and safety of cilostazol, a novel phosphodiesterase inhibitor in patients with intermittent claudication 显示文摘 | SAMRA S S BAJAJ P VUAYARAGHAVAN K S | 2003 | J Indian Med Assoc2003，101，9： | 1 |
| 18 | 250 GHz CW Gyration Oscillator for Dynamic Nuclear Polarization in Biological Solid State NMR显示文摘 | Bajaj V S Hornstein M K Kreischer K E | 2009 | J Magn Res2009，189，： | 1 |
| 19 | Occupational and systemic contact dermatitis with photosensitivity due to vitamin B6 显示文摘 | Bajaj AK Rastogi S Misra A | 2001 | Contact Dermatitis2001，44，3： | 1 |
| 20 | Thermal behavior of acrylonitrile carboxylic acid copolymers 显示文摘 | Bahrami S I-I Bajaj P Sen K | 2003 | Journal of Applied Polymer Science2003，88，： | 1 |
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