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9篇 您的检索式:作者名="Bakhshinejad"
    题名 作者 年代 出处 被引量
1Bacteriophages and their applications in the diagnosis and treatment of hepatitis B virus infection显示文摘Hepatitis B virus(HBV) infection is a major global health challenge leading to serious disorders such as cirrhosis and hepatocellular carcinoma. Currently, there exist various diagnostic and therapeutic approaches for HBV infection. However, prevalence and hazardous effects of chronic viral infection heighten the need to develop novel methodologies for the detection and treatment of this infection. Bacteriophages, viruses that specifically infect bacterial cells, with a long-established tradition in molecular biology and biotechnology have recently been introduced as novel tools for the prevention, diagnosis and treatment of HBV infection. Bacteriophages, due to tremendous genetic flexibility, represent potential to undergo a huge variety of surface modifications. This property has been the rationale behind introduction of phage display concept. This powerful approach, together with combinatorial chemistry, has shaped the concept of phage display libraries with diverse applications for the detection and therapy of HBV infection. This review aims to offer an insightful overview of the potential of bacteriophages in the development of helpful prophylactic(vaccine design), diagnostic and therapeutic strategies for HBV infection thereby providing new perspec-tives to the growing field of bacteriophage researches directing towards HBV infection.Babak Bakhshinejad Majid Sadeghizadeh 2014World Journal of Gastroenterology2014,20,33:5
2Phage display: development of nanocarriers for targeted drug delivery to the brain显示文摘The blood brain barrier represents a formidable obstacle for the transport of most systematically administered neurodiagnostics and neurotherapeutics to the brain. Phage display is a high throughput screening strategy that can be used for the construction of nanomaterial peptide libraries. These libraries can be screened for finding brain targeting peptide ligands. Surface functionalization of a variety of nanocarriers with these brain homing peptides is a sophisticated way to develop nanobiotechnology-based drug delivery platforms that are able to cross the blood brain barrier. These efficient drug delivery systems raise our hopes for the diagnosis and treatment of various brain disorders in the future.Babak Bakhshinejad Marzieh Karimi Mohammad Khalaj-Kondori 2015Neural Regeneration Research2015,10,6:2
3Human bocavirus in Iranian children with acute respiratory infections显示文摘Naghipour M Cueves LE Bakhshinejad T 0,,05:1
4Human bocavirus in Iranian children with acute respiratory infections显示文摘Naghipour M Cuevas LE Bakhshinejad T 2007J Med Virol2007,79,5:1
5Cell-free microRNAs as cancer biomarkers: the odyssey of miRNAs through body fluids显示文摘Mohammad Amin Javidi Amir Hossein Ahmadi Babak Bakhshinejad Nazila Nouraee Sadegh Babashah Majid Sadeghizadeh 2014Medical Oncology2014,,:1
6Human bocavims in Iranian children with acute respiratory infections 显示文摘Naghipour M Cuevas L E Bakhshinejad T 2007J Med Virol2007,79,5:1
7Bacteriophagesand medical oncology: targeted gene therapy of cancer显示文摘Bakhshinejad B Karimi M Sadeghizadeh M 2014MedOncol2014,31,8:1
8Bacteriophages and development of nanomaterials for neural regeneration显示文摘Bacteriophages(phages)are viruses that infect bacterial cells and hijack the metabolism of the host cells for replication and amplification of their genetic information.These bacterial viruses are known to be the most numerous life forms on earth.Recent metagenomic analyses have revealed the vast untapped diversity of bacteriophages reinforcingBabak Bakhshinejad Majid Sadeghizadeh 2014Neural Regeneration Research2014,9,22:1
9Swirling flows in horizontally vibrated beds of dense granular materials显示文摘In a series of experiments,a granular material in a rectangular container with two hollow cylinders was studied as it underwent horizontal vibrations.At the peak values of acceleration,novel swirling granular flows were observed in the cylinders while the grains cascaded down the outer surface of the piles that formed outside the cylinders.Computer simulations were performed that supported our interpretation of the behaviour observed in the experiments.Ali Bakhshinejad Piroz Zamankhan 2012Particuology2012,10,6:0
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