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| 1 | Outcomes of severe sepsis and septic shock patients after stratifi cation by initial lactate value显示文摘BACKGROUND: In the setting of severe sepsis and septic shock, mortality increases when lactate levels are ≥ 4 mmol/L. However, the consequences of lower lactate levels in this population are not well understood. The study aimed to determine the in-hospital mortality associated with severe sepsis and septic shock when initial lactate levels are < 4 mmol/L.METHODS: This is a retrospective cohort study of septic patients admitted over a 40-month period. Totally 338 patients were divided into three groups based on initial lactate values. Group 1 had lactate levels < 2 mmol/L; group 2: 2–4 mmol/L; and group 3: ≥ 4 mmol/L. The primary outcome was in-hospital mortality.RESULTS: There were 111 patients in group 1, 96 patients in group 2, and 131 in group 3. The mortality rates were 21.6%, 35.4%, and 51.9% respectively. Univariate analysis revealed the mortality differences to be statistically significant. Multivariate logistic regression demonstrated higher odds of death with higher lactate tier group, however the findings did not reach statistical significance.CONCLUSION: This study found that only assignment to group 3, initial lactic acid level of ≥ 4 mmol/L, was independently associated with increased mortality after correcting for underlying severity of illness and organ dysfunction. However, rising lactate levels in the other two groups were associated with increased severity of illness and were inversely proportional to prognosis. | Kimberly A. Chambers Adam Y. Park Rosa C. Banuelos Bryan F. Darge Bindu H. Akkanti Annamaria Macaluso Manoj Thangam Pratik B. Doshi | 2018 | World Journal of Emergency Medicine2018，9，2： | 26 |
| 2 | Initial results and long-term clinical and angiographic outcome of coronary stenting in women显示文摘 | Alfonso F Hernandez R Banuelos C | 2000 | Am J Cardiol2000，86，12： | 1 |
| 3 | Vegetative pro- duction of kenaf and canola under irrigation in central Califor- nia显示文摘 | BANUELOS G S BRYLA D R COOK C G | 2002 | Industrial Crops and Products2002，15，3： | 1 |
| 4 | Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis 显示文摘 | Bowen RE Scaduto AA Banuelos S | 2008 | J Pediatr Orthop2008，28，6： | 1 |
| 5 | Selenium bio- fortification of broccoli and carrots grown in soil amended with Se-enriched hyperaccumulatorStanleyapinnata 显示文摘 | Banuelos G S Arroyo I Picketing I J | 2015 | Food Chem2015，166，： | 1 |
| 6 | Evaluation of commercial enzyme-linked immunosorbent assays to identify psychedelic phenethylamines显示文摘 | Kerrigan S Mellon M B Banuelos S | 2011 | J Anal Toxicol2011，35，7： | 1 |
| 7 | Accumulation of selenium in plant grown on selenium-treated soil显示文摘 | BANUELOS O S | 1990 | J Environ Qual1990，19，： | 1 |
| 8 | Neocarzinostatin induces an effective p53-dependent response in human papillomavirus positive cervical cancer cells显示文摘 | BANUELOS A REYES E OCADIZ R | 2003 | J Pharmacol Exp Ther2003，306，2： | 1 |
| 9 | The NHA1 anti- porter of Saccharomyces cerevisiae mediates sodium and potassium efflux 显示文摘 | Banuelos M A Sychrova H Bleykasten G C | 1998 | Micobiology1998，144，10： | 1 |
| 10 | Using compost wood chip materials as biofilterials as biofiltration media显示文摘 | Jones Kim D Banuelos Christina | 2000 | Biocycle2000，41，10： | 1 |
| 11 | Crop selection for removing selenium from the soil显示文摘 | BANUELOS G S | 1989 | Calif Agric1989，43，： | 1 |
| 12 | Sodium transport and HKT transporters:The rice model显示文摘 | GARCIADEBLS B SENN M E BANUELOS M A | 2003 | The plant journal2003，34，： | 1 |
| 13 | Radiosensitization by the histone deacetylase inhibitor PCI-24781显示文摘 | Banuelos C A Banath J P Macphail S H | 2007 | Clin Cancer Res2007，15，32： | 1 |
| 14 | Inventory and functional characterization of the HAK potassium transporters of rice显示文摘 | Banuelos M A Garciadeblas B Cubero B Navarro R N | 2002 | Plant Physiology2002，130，2： | 1 |
| 15 | Boron toxicity显示文摘 | Nable R O Banuelos G S Paull J G | 1997 | Plant and Soil1997，193，： | 1 |
| 16 | Evaluation of different plant-species used in phytoremediation of high soil selenium显示文摘 | Banuelos G S Ajwa H A Mackey B | 1997 | Journal of Environmental Quality1997，26，3： | 1 |
| 17 | Effectiveness of percutancous coronary interventions in nonagenarians显示文摘 | Salazar A Banuelos C | 2004 | Am J Cardiol2004，94，： | 1 |
| 18 | Effectiveness of percuta neous coronary interventions in nonagenarians显示文摘 | Moreno R Salazar A Banuelos C | 2004 | Am Cardio2004，94，8： | 1 |
| 19 | Synthesis, characterization, and evaluation of antimicrobial and cytotoxic effect of silver and titanium nanoparticles显示文摘 | Fidel Martinez-Gutierrez Peggy L. Olive Adriana Banuelos Erasmo Orrantia Nereyda Nino Elpidio Morales Sanchez Facundo Ruiz Horacio Bach Yossef Av-Gay | 2010 | Nanomedicine: Nanotechnology Biology and Medicine2010，，5： | 1 |
| 20 | Neocarzinostatin induces an effective p53-dependent response in human papillomavirus-positive cervical cancer cells 显示文摘 | Reyes E Ocadiz R | 2003 | J Pharmacol Exp Ther2003，306，2： | 1 |
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