|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Non-alcoholic fatty liver disease: What has changed in the treatment since the beginning?显示文摘Non-alcoholic fatty liver disease(NAFLD) is an umbrella term to describe the entire spectrum of this common liver disease. In patients with NAFLD, especially those with non-alcoholic steatohepatitis(NASH), most often have one or more components of the metabolic syndrome, but this is not universal. Although most patients with NAFLD share many clinical features, only a subset of patients develops significant liver inflammation and progressive fibrosis. On the other hand, not all patients with NASH exhibit insulin resistance. NASH can be seen in patients who are lean and have no identifiable risk factors. Many clinical studies have tried numerous drugs and alternative medicine, however, investigators have failed to identify a safe and effective therapy for patients with NASH. As summarized, the heterogeneity of pathogenic pathways in individual patients with NASH may warrant the development of an individualized treatment according to the underlying pathogenic pathway. The differentiation of pathogenetic targets may require the development of diagnostic and prognostic biomarkers, and the identification of genetic susceptibilities. At present, evidence-based medicine provides only a few options including life-style modifications targeting weight loss, pioglitazone and vitamin E in non-diabetic patients with biopsy-proven NASH. | Bülent Baran Filiz Akyüz | 2014 | World Journal of Gastroenterology2014，20，39： | 10 |
| 2 | Gastroesophageal reflux in asymptomatic obese subjects:An esophageal impedance-pH study显示文摘AIM:To investigate the relationship between reflux and body mass index(BMI) in the asymptomatic obese population using the impedance-p H technique.METHODS:Gastroesophageal reflux is frequent in the obese population.However,the relationship between acid reflux and BMI in asymptomatic obese people is unclear.Forty-six obese(BMI > 25 kg/m2) people were enrolled in this prospective study.We evaluated the demographic findings and 24-h impedance p H values of the whole group.Gas,acid(p H < 4),weak acid(p H = 4-7) and weak alkaline(p H ≥ 7) reflux parameters were analyzed.RESULTS:The mean age of patients was 49.47±12.24 years,and half of them were men.The mean BMI was 30.64±3.95 kg/m2(25.14-45.58 kg/m2).BMI of 23 was over 30 kg/m2.Seventeen patients had a comorbidity(hypertension,diabetes mellitus,or ischemic heart disease).Endoscopic examination revealed esophagitis in 13 of the 28 subjects(10Grade A,3 Grade B).The subjects were divided into two groups according to BMI(<30 and>30 kg/m2).Demographic and endoscopic findings,and impedance results were similar in these two groups.However,there was a positive correlation between BMI and total and supine p H<4 episodes(P=0.002,r=0.414;P=0.000,r=0.542),p H<4 reflux time(P=0.015,r=0.319;P=0.003,r=0.403),and De Meester score(P=0.012,r=0.333).CONCLUSION:Acid reflux is correlated with BMI in asymptomatic obese individuals. | Filiz Akyüz Ahmet Uyanikoglu Fatih Ermis Serpil Arici ümit Akyüz Divison of Gastroenterology Department of Internal Medicine Faculty of Medicine Yeditepe University Bülent Baran Binnur Pinarbasi Nurdan Gul | 2015 | World Journal of Gastroenterology2015，21，10： | 3 |
| 3 | Dispatch of hydroelectric generating units using multi-objective evolutionary algorithms显示文摘 | Villasanti C M Von Lucken C Baran B | 2004 | IEEE Trans on Power Systems2004，19，8： | 1 |
| 4 | Efficacy of tenofovir in patients with Lamivudine failure is not different from that in nucleoside/nucleotide analogue-naive patients with chronic hepatitis B 显示文摘 | Baran B Soyer OM Ormeci AC | 2013 | Antimicrob Agents Chemother2013，57，4： | 1 |
| 5 | Effect of cytochrome P450 2C19 po]qmorphisms on the Helicobaeter pylori eradication rate following two-week triple therapy with pantoprazole or rabeprazole 显示文摘 | Ormeci A Emrence Z Baran B | 2016 | Eur Rev Med Pharmacol Sci2016，20，5： | 1 |
| 6 | Knowledge management and online com- munities of practice in teacher education显示文摘 | Baran B Cagihay K | 2006 | The Turkish On- line Journal of Educational Technology2006，，5： | 1 |
| 7 | Can Helicobacter pylori be eradicated with high-dose proton pump inhibitor in extensive metabolizers with the CYP2C19 genotypic polymorphism? 显示文摘 | Ormeci A Emrence Z Baran B et at | 2016 | Eur Rev Med Pharmacol Sci2016，20，9： | 1 |
| 8 | Does central venous pressure pre- dict fluid responsiveness显示文摘 | Marik PE Baran M Vallid B | 2008 | Chest2008，134，1： | 1 |
| 9 | Effect of pectinase on rumen fermentation in sheep and lambs显示文摘 | BARAN M KMET B | 1987 | Arch Anim Nutr Berlin1987，8，： | 1 |
| 10 | Small arterial elasticity predicts the extent of coronary artery disease: Relationship with serum uric acid显示文摘 | Murat Fazl?o?lu Tunay ?entürk Ethem Kumbay Aysel Ayd?n Kaderli Yusuf Yilmaz Bülent ?zdemir ?brahim Baran Ali Ayd?nlar | 2008 | Atherosclerosis2008，，1： | 1 |
| 11 | Effects of glucose-insulin-potassium solution added to reperfusion treatment in acute myocardial infarction 显示文摘 | Turel B Gemici K Baran I | 2005 | Anadolu Kardiyol Derg2005，5，2： | 1 |
| 12 | Association of MMP - 12 polymorphisms withsevere and very severe COPD:A case controlstudy of MMPs - 1,9 and 12 in a European population 显示文摘 | Haq I Chappell S Johnson S R Lotya J Daly L Morgan K Guetta - Baranes T Roca J Rabinovich R Millar A B Donnelly S C Keatings V MacNee W Stolk J Hiemstra P S Miniati M Monti S Connor C M Kalsheker N | 2010 | BMC Medical Genetics2010，15，11： | 1 |
| 13 | Biomechanical analysis of load transmission characteristics of limited carpal fusions used to treat Kienbock's disease显示文摘 | Ozcan O Uyulgan B Baran O | 2005 | Acta Orthop Traumatol Turc2005，39，4： | 1 |
| 14 | Team algorithms in distributed load flow computations 显示文摘 | Baran B | 1995 | IEE Proc-GenerTrans Distrib1995，142，6： | 1 |
| 15 | Synthesis and characterization of oxovanadium (IV) complexes with saccharides显示文摘 | Etcheverry S B Williams P A M Baran E J | 1997 | Carbohydrate research1997，302，3： | 1 |
| 16 | A survey on multi-objective evolutionary algorithms for many-objective problems显示文摘 | VON LOCKEN C BARAN B BRIZUELA C | 2014 | Computational Optimization and Applications2014，58，3： | 1 |
| 17 | Parallel asynchronous team algorithms: convergence and performance analysis显示文摘 | Baran B | 1996 | 1EEE Transactions on Parallel and Distributed Systems1996，7，7： | 1 |
| 18 | A modification to the Goldstein radar interferogram filter显示文摘 | Baran L Stewart M P Kampes B M | 2003 | IEEE Transactions on Geoscience and Remote Sensing2003，41，9： | 1 |
| 19 | The levels of the circulating cellular adhe- sion molecules ICAM-1,VCAM-1 and endothelin-1 and the flow-mediated vasodilatation values in patients with type I diabetes mellitus with early-stage diabetic retinopathy 显示文摘 | UGURLU N GERCEKER S YLEK F UGURLU B SARI C BARAN P | 2013 | Intern Med2013，52，19： | 1 |
| 20 | Anatomical and biomechanical evaluation of the tension band technique in patellar fractures显示文摘 | Baran () Manisali M Cecen B | | 0，，04： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员