| 3 | Cervical cancer in Calabar,Nigeria显示文摘Objective: To assess the prevalence of cervical cancer and histologic variants as seen in Calabar,Cross River state.Methods: This is a retrospective study involving histologically verified uterine cervix carcinoma between January,1997 and December,2006.Results: There were 1,207 malignancies diagnosed during the study period;175(14.5%) were malignancies of the genital tract while 113(9.4.0%) were carcinoma of the cervix constituting 64.6% of female genital malignancies.Cervical cancer was commonest between the ages of 40-59 years.There was no patient with carcinoma of the cervix below the age of 20 years.Squamous cell carcinoma(87.6%) of the uterine cervix was the main histological type.Conclusion:Cervical cancer is still the most common female genital tract malignancy in Calabar with most of these patients in their middle age.The use of PAS/Alcian blue stain as was used in this study eliminates most false-positive squamous cell carcinomas compared with Haematoxylin and Eosin stains used in most reports from most centres in this part of the world.Epithelial malignancies continue to be the predominant histological variant with squamous cell variety the commonest.There is also an urgent need for introduction of efficient and affordable population based cervical screening programme for early detection,use of vaccines against Human Papilloma Virus(HPV) and treatment of pre-malignant cervical lesions. | Omotoso AJ Agan TU Bassey IE Ebughe GA Ekanem IA Ekanem AD | 2010 | 海南医学院学报2010，16，1： | 0 |
| 4 | HIV/AIDS related mortality among adult medical patients in a tertiary health institution in South-South,Nigeria显示文摘Objective:To determine the causes of death among human immunodeficiency virus/acquired immunodeficiency syndrome(HIV/AIDS) patients as a step to planning strategies to improve mortality from this condition.Methods:This study retrospectively analyzed the mortality pattern of adult HIV/AIDS patients in the University of Calabar Teaching Hospital from January 2005 to December 2007.The data were obtained from sexually transmitted infection/acquired immunodeficiency syndrome(STI/AIDS) clinic register,admissions and discharge/death registers as well as the patients’ case records and the hospitals monthly mortality reviews.Information obtained included age,sex,diagnosis and cause(s) of death.The causes of death considered were the direct causes of death,since the originating antecedent cause of death is the same in all the patients,in this case,HIV/AIDS.Data was analysed using Epi Info 2002.Results:The total number of mortalities during the study period was 350,100 were HIV positive representing 28.6%of all deaths.While advanced HIV/AIDS disease was the leading cause of death in our study representing 27.0%,tuberculosis was the single leading cause of deaths in HIV/AIDS patients constituting about 24.0%of deaths.This was followed by sepsis and septicaemia(13.0%), meningitis and encephalitis,and anaemia accounting for 11.0%,while respiratory diseases constituted 5.0%of the mortality burden.The highest number of deaths occurred in those aged between 21-50 years(82.0%).Conclusions:The study has shown that HIV/AIDS is a major cause of morbidity and mortality in our hospital.The causes of death reflect the varied spectrum of infection and other forms of organ involvement that affect HIV/AIDS patients.The present dismal situation of adult patients living with HIV/AIDS calls for enhanced strategies to decrease the mortality trend observed in Nigeria and sub-Saharan Africa. | Gyuse AN Bassey IE Udonwa NE Okokon IB Philip-Ephraim EE | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，2： | 0 |
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