|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | End-stage renal disease is associated with increased post endoscopic retrograde cholangiopancreatography adverse events in hospitalized patients显示文摘AIM To determine if end-stage renal disease (ESRD) is a risk factor for post endoscopic retrograde cholangio-pancreatography (ERCP) adverse events (AEs). METHODS We performed a retrospective cohort study using the Nationwide Inpatient Sample (NIS) 2011-2013. We identified adult patients who underwent ERCP using the International Classification of Diseases 9^(th) Revision (ICD-9-CM). Included patients were divided into three groups: ESRD, chronic kidney disease (CKD), and control. The primary outcome was post-ERCP AEs including pancreatitis, bleeding, and perforation determined based on specific ICD-9-CM codes. Secondary outcomes were length of hospital stay, in-hospital mortality, and admission cost. AEs and mortality were compared using multivariate logistic regression analysis.RESULTS There were 492175 discharges that underwent ERCP during the 3 years. The ESRD and CKD groups contained 7347 and 39403 hospitalizations respectively, whereas the control group had 445424 hospitalizations. Post-ERCP pancreatitis (PEP) was significantly higher in the ESRD group (8.3%) compared to the control group (4.6%) with adjusted odd ratio (aOR) = 1.7 (95% CI: 1.4-2.1, ~aP < 0.001). ESRD was associated with significantly higher ERCP-related bleeding (5.1%) compared to the control group 1.5% (aOR = 1.86, 95%CI: 1.4-2.4, ~aP < 0.001). ESRD had increased hospital mortality 7.1% vs 1.15% in the control OR = 6.6 (95%CI: 5.3-8.2, ~aP < 0.001), longer hospital stay with adjusted mean difference (aMD) = 5.9 d (95% CI: 5.0-6.7 d, ~aP < 0.001) and higher hospitalization charges aMD = $+82064 (95%CI: $68221-$95906, ~aP < 0.001). CONCLUSION ESRD is a risk factor for post-ERCP AEs and is associated with higher hospital mortality. Careful selection and close monitoring is warranted to improve outcomes. | Tarek Sawas Fateh Bazerbachi Samir Haffar Won K Cho Michael J Levy John A Martin Bret T Petersen Mark D Topazian Vinay Chandrasekhara Barham K Abu Dayyeh | 2018 | World Journal of Gastroenterology2018，24，41： | 2 |
| 2 | 内镜下胰管支架置入术用于缓解胰腺癌患者的疼痛:系统综述与meta分析显示文摘背景:腹痛是一种致人衰弱的症状,大约80%的胰腺癌患者都会出现腹痛。胰管减压虽然未被广泛采纳,但有报道该方法能缓解腹痛症状。本研究旨在评估内镜下胰管减压对于缓解胰腺癌患者餐后梗阻型腹痛的作用、效果及安全性。方法:该系统综述的文献检索时间截至2020年10月7日。由两位研究者独立地筛选文献、提取数据,并对文献质量进行评估。结果:12篇文献共计192例有腹痛症状且尝试胰管减压的胰腺癌患者纳入研究。其中,167例患者成功完成胰管减压(平均年龄62.5岁,58.7%为男性)。159(95.2%)例患者采用塑料支架。所有被纳入的研究均报道了胰管支架置入术后患者疼痛部分或完全缓解,缓解率为93%(95%CI:79%-100%)。平均的疼痛缓解期为94˘16天。内镜逆行性胰胆管造影(ERCP)相关的不良反应包括括约肌切开术后出血(1.8%)、ERCP后胰腺炎(0.6%)和胰管出血(0.6%)。2例行内镜超声引导的胰管减压患者未报道任何不良反应。在成功置入支架的167例患者中,支架移位和支架阻塞的发生率分别为3.6%和3.0%。未报道不良反应相关的死亡病例。文献质量评估提示,绝大部分文献质量较低或难以评价。结论:初步分析结果表明,对于部分经选择的胰腺癌病例,内镜下胰管引流可能是缓解梗阻型疼痛一种安全有效的方法。但该侵入性方法的作用尚需随机对照研究来进一步明确。 | Pradeep K.Siddappa Fadi Hawa Larry J.Prokop MHassan Murad Barham K.Abu Dayyeh Vinay Chandrasekhara Mark D.Topazian Fateh Bazerbachi | 2021 | Gastroenterology Report2021，9，2： | 2 |
| 3 | Normothermic Acellular Ex Vivo Liver Perfusion Reduces Liver and Bile Duct Injury of Pig Livers Retrieved After Cardiac Death显示文摘 | M. U. Boehnert J. C. Yeung F. Bazerbachi J. M. Knaak N. Selzner I. D. McGilvray O. D. Rotstein O. A. Adeyi S. M. Kandel P. Rogalla P. M. Yip G. A. Levy S. Keshavjee D. R. Grant M. Selzner | 2013 | American Journal of Transplantation2013，，6： | 1 |
| 4 | Making the case for the development of a vaccination against hepatitis E virus显示文摘 | Samir Haffar Fateh Bazerbachi John R. Lake | 2015 | Liver Int2015，，2： | 1 |
| 5 | 回肠储袋肛管吻合术后储袋扭转:对其发生率、诊断和治疗结局的系统综述显示文摘背景:结直肠切除加回肠储袋肛管吻合术(IPAA)是难治性溃疡性结肠炎和家族性腺瘤性息肉病的标准外科术式。然而,储袋扭转时有发生,尽管发生率很低。本研究旨在探讨IPAA患者术后储袋扭转的发生率、临床表现和治疗。方法:于2018年8月10日通过医学文献图书馆系统检索已发表的文献,由两名独立的研究人员分别进行文献筛选、数据提取、方法学质量评估。同时,检索美国Mayo Clinic 2008年1月至2018年8月间的电子病历发现了1例储袋扭转病例。结果:一项报道了IPAA长期结局的大样本研究显示,储袋扭转发生率为0.18%(3/1700)。本研究共纳入22例储袋扭转患者进行分析,其中18例原发疾病为溃疡性结肠炎。全组病例中位年龄32岁,女性占73%。IPAA术后出现储袋扭转的中位时间为36个月,出现首发症状至诊断储袋扭转的中位时间为24小时。腹痛是最常报道的症状(76%)。多数病例是经腹部CT作出初步诊断(76%,13/17)。11例患者行内镜治疗,仅1例(9%)成功。20例患者行手术治疗,最常采用的手术方式是储袋固定术和储袋切除术。5例(25%)患者接受了再次IPAA手术。结论:储袋扭转是IPAA术后一种罕见但严重的并发症,出现梗阻症状时应考虑储袋扭转的可能。内镜治疗成功率非常低;如果能早期诊断、早期手术,手术治疗疗效确切。 | Muhammad Jawoosh Samir Haffar Parakkal Deepak Alyssa Meyers Amy L.Lightner David W.Larson Laura H.Raffals MHassan Murad Navtej Buttar Fateh Bazerbachi | 2019 | Gastroenterology Report2019，7，6： | 1 |
| 6 | Normothermie a- cellular ex viva liver perfusion reduces liver and bile duct injury of pig livers retrieved after cardiac death显示文摘 | Boehnert MU Yeung JC Bazerbachi 17 | 2013 | Am J Transplant2013，13，6： | 1 |
| 7 | Endo-anesthesia:a primer显示文摘Gastrointestinal(GI)endoscopy has witnessed a Cambrian explosion of techniques,indications,and expanding target populations.GI endoscopy encompasses traditional domains that include preventive measures,palliation,as alternative therapies in patients with prohibitive risks of more invasive procedures,and indicated primary treatments.But,it has expanded to include therapeutic and diagnostic interventional endosonography,luminal endoscopic resection,third space endotherapy,endohepatology,and endobariatrics.The lines between surgery and endoscopy are blurred on many occasions within this paradigm.Moreover,patients with high degrees of co-morbidity and complex physiology require more nuanced peri-endoscopic management.The rising demand for endoscopy services has resulted in the development of endoscopy referral centers that offer these invasive procedures as directly booked referrals for regional and rural patients.This further necessitates specialized programs to ensure appropriate evaluation,risk stratification,and optimization for safe sedation and general anesthesia if needed.This landscape is conducive to the organic evolution of endo-anesthesia to meet the needs of these focused and evolving practices.In this primer,we delineate important aspects of endo-anesthesia care and provide relevant clinical and logistical considerations pertaining to the breadth of procedures. | Fateh Bazerbachi Rodger M.White Nauzer Forbes Basavana Goudra Barham K.Abu Dayyeh Vinay Chandrasekhara BobbieJean Sweitzer | 2022 | Gastroenterology Report2022，10，1： | 1 |
| 8 | Early precursor of mixed endocrine-exocrine tumors of the gastrointestinal tract : his- tologic and molecular correlations 显示文摘 | Bazerbachi F Kermanshahi TR Monteiro C | 2015 | Ochsner J2015，15，1： | 1 |
| 9 | A comparative study of the use of selective digestive decontamination prophylaxis in living‐donor liver transplant recipients显示文摘 | E. Katchman M. Marquez F. Bazerbachi D. Grant M. Cattral C.Y. Low E. Renner A. Humar M. Selzner A. Ghanekar C. Rotstein S. Husain | 2014 | Transpl Infect Dis2014，，4： | 1 |
| 10 | Portal venous versus systemic venous drainage of pancreas grafts : impact on long-term results 显示文摘 | Bazerbachi F Selzner M Marquez MA | 2012 | Am J Transplant2012，12，1： | 1 |
| 11 | Making the case for the development of a vaccination against hepatitis E virus显示文摘 | HAFFAR S BAZERBACHI F LAKE J R | 2015 | Liver Int2015，35，2： | 1 |
| 12 | 戊肝病毒感染相关的混合性冷球蛋白血症的系统综述:相关关系还是因果关系?显示文摘背景与目的:混合性冷球蛋白血症(MC)已显示与一些病毒感染有关,其中慢性丙型肝炎被认为是MC发生一个主要原因。有研究报道了戊肝病毒(HEV)相关的MC,但对于这种罕见的关系所知甚少。本研究的目的是对HEV相关的MC进行系统综述,评估两者之间是否存在因果关系。方法:由一位经验丰富的图书馆情况员按照先验标准,对每一个数据库截至2016年12月12日的文献进行检索。评估偏倚风险;采用Hill标准判断因果关系。结果:5项研究满足纳入标准,共计15例病例。偏倚风险评估结果显示,3项研究为低风险,1项中低风险,1项中等风险。入组病例中位年龄43岁,所有病例都来自西欧。2例患者免疫功能正常,13例免疫抑制,系实体器官移植后同时合并慢性戊型肝炎。7例患者出现肾脏病变,其中1例为轻中度冷球蛋白血症,3例为重度冷球蛋白血症。1例患者自行改善,1例患者在在减少免疫抵制剂的剂量后HEV得以清除。10例患者接受聚乙二醇干扰素或病毒唑治疗3个月,所有病例冷球蛋白血症消失且均获治疗结束病毒学应答,但仅2例患者获得持续病毒学应答。3例患者接受免疫抑制剂治疗后,冷球蛋白血症均消失。最终,1例患者出现慢性肾功能衰竭,3例患者发展为终末期肾病,1例患者死亡。因果关系分析显示,9项Hill标准满足5项。结论:MC与HEV感染有关,且HEV与MC之间很可能存在一个因果关系。 | Fateh Bazerbachi Michael D.Leise Kymberly D.Watt MHassan Murad Larry J.Prokop Samir Haffar | 2017 | Gastroenterology Report2017，5，3： | 1 |
| 13 | Normothermic acellular ex vivo liver perfusion reduces liver and bile duct injury of pig livers retrieveed after cardiac death显示文摘 | Boehnert MU Yeung JC Bazerbachi F | 2013 | Am J Transplant2013，13，6： | 1 |
| 14 | 静脉注射异丙酚引起的急性胰腺炎:通过系统综述评估其因果关系显示文摘背景:异丙酚注射引起急性胰腺炎(AP)已有报道,但两者之间的因果关系尚不明了。因此,我们通过系统综述对其因果关系进行评估。方法:我们于2017年8月16日对多个数据库进行检索,由两人按预设标准对检索出的研究进行评估和筛选。使用Naranjo量表和Badalov分级评估异丙酚注射与AP的因果关系。结果:我们筛选出来自11个国家的18项研究,病例总数为21例,大多数研究都有高质量的方法学。21例患者中位年龄35岁(4-77岁),10例(48%)为男性。8例患者注射异丙酚是用于镇静,13例为麻醉诱导/维持,异丙酚中位注射剂量为200 mg。14例(67%)患者具有一个中等时长(1-30天)的潜伏期(异丙酚注射至AP诊断)。4例患者甘油三酯水平>1000 mg/dL。4例(19%)患者出现严重AP。2例患者在AP治疗好转后再次接受异丙酚注射,其中1例出现了AP复发。AP相关病死率为14%(3/21)。按Naranjo量表评估,在19例(89%)患者中,异丙酚注射是AP的可能原因。结论:在Badalov Ib级别的证据支持下,可以认为异丙酚注射是AP发生的一个可能原因。高甘油三酯血症并不是异丙酚诱发AP的唯一机制。异丙酚引起的AP中,有19%为严重AP,病死率高达14%。未来研究需要评估如果合并应用其他一些本身就有导致胰腺炎风险的操作(如ERCP),异丙酚引起的AP发生概率是否会增加。 | Samir Haffar Ravinder Jeet Kaur Sushil Kumar Garg Joseph A.Hyder M.Hassan Murad Barham K.Abu Dayyeh Fateh Bazerbachi | 2019 | Gastroenterology Report2019，7，1： | 1 |
| 15 | Turnkey algorithmic approach for the evaluation of gastroesophageal reflux disease after bariatric surgery显示文摘Bariatric surgeries are often complicated by de-novo gastroesophageal reflux disease(GERD)or worsening of pre-existing GERD.The growing rates of obesity and bariatric surgeries worldwide are paralleled by an increase in the number of patients requiring post-surgical GERD evaluation.However,there is currently no standardized approach for the assessment of GERD in these patients.In this review,we delineate the relationship between GERD and the most common bariatric surgeries:sleeve gastrectomy(SG)and Roux-en-Y gastric bypass(RYGB),with a focus on pathophysiology,objective assessment,and underlying anatomical and motility disturbances.We suggest a stepwise algorithm to help diagnose GERD after SG and RYGB,determine the underlying cause,and guide the management and treatment. | Omar M.Ghanem Rabih Ghazi Farah Abdul Razzak Fateh Bazerbachi Karthik Ravi Leena Khaitan Shanu N.Kothari Barham K.Abu Dayyeh | 2023 | Gastroenterology Report2023，11，1： | 0 |
| 16 | Superiority of urgent vs early endoscopic hemostasis in patients with upper gastrointestinal bleeding with high-risk stigmata显示文摘Background Guidelines recommend that all patients with upper gastrointestinal bleeding(UGIB)undergo endoscopy within 24 h.It is unclear whether a subgroup may benefit from an urgent intervention.We aimed to evaluate the influence of endoscopic hemostasis and urgent endoscopy on mortality in UGIB patients with high-risk stigmata(HRS).Methods Consecutive patients with suspected UGIB were enrolled in three Japanese hospitals with a policy to perform endoscopy within 24 h.The primary outcome was 30-day mortality.Endoscopic hemostasis and endoscopy timing(urgent,6h;early,>6h)were evaluated in a regression model adjusting for age,systolic pressure,heart rate,hemoglobin,creatinine,and variceal bleeding in multivariate analysis.A propensity score of 1:1 matched sensitivity analysis was also performed.Results HRS were present in 886 of 1966 patients,and 35 of 886(3.95%)patients perished.Median urgent-endoscopy time(n=769)was 3.0h(interquartile range[IQR],2.0–4.0 h)and early endoscopy(n紏117)was 12.0h(IQR,8.5–19.0 h).Successful endoscopic hemostasis and urgent endoscopy were significantly associated with reduced mortality in multivariable analysis(odds ratio[OR],0.22;95%confidence interval[CI],0.09–0.52;P=0.0006,and OR,0.37;95%CI,0.16–0.87;P=0.023,respectively).In a propensity-score-matched analysis of 115 pairs,adjusted comparisons showed significantly lower mortality of urgent vs early endoscopy(2.61%vs 7.83%,P<0.001).Conclusions A subgroup of UGIB patients,namely those harboring HRS,may benefit from endoscopic hemostasis and urgent endoscopy rather than early endoscopy in reducing mortality.Implementing triage scores that predict the presence of such lesions is important. | Masayasu Horibe Eisuke Iwasaki Juntaro Matsuzaki Fateh Bazerbachi Tetsuji Kaneko Kazuhiro Minami Seiichiro Fukuhara Tatsuhiro Masaoka Naoki Hosoe Yuki Ogura Shin Namiki Yasuo Hosoda Haruhiko Ogata Takanori Kanai | 2021 | Gastroenterology Report2021，9，6： | 0 |
| 17 | Horibe胃肠出血预测评分(HARBINGER)用于上消化道出血重症患者的内镜治疗效果的预测显示文摘We read with great interest the study by Rao et al.[1]Rao and colleagues showed that the Rockall score,Glasgow-Blatchford score(GBS)and AIMS65 are poorly predictive of 30-day mortality,or the need for endoscopic intervention in intensive care unit(ICU)patients with an upper GI bleed(UGIB).The Rockall[2]score and AIMS65[3]were developed for predicting mortality,whereas the GBS[4]was developed for predicting composite outcomes(The need for a blood transfusion or intervention to control bleeding,rebleeding,or death)We were not surprised to see that these scores were poor predictors of endoscopic intervention,as they were not designed to predict high-risk endoscopic stigmata(HRS),which is arguably a very meaningful endpoint to determine the need for endoscopic intervention. | Fateh Bazerbachi Masayasu Horibe | 2021 | Gastroenterology Report2021，9，1： | 0 |
| 18 | 内镜下氰基丙烯酸酯注射联合胃肾分流球囊闭塞下逆行经静脉栓塞术(BRTOcc)治疗胃底静脉曲张出血的有效性和安全性显示文摘背景:内镜下氰基丙烯酸酯注射治疗胃底静脉曲张,可能会通过自发性胃肾分流导致严重的栓塞性事件。在内镜下氰基丙烯酸酯注射时,对胃肾分流进行球囊闭塞下逆行经静脉栓塞术(BRTOcc)或可预防因胃肾分流造成的严重系统性栓塞。本研究旨在评估联合BRTOcc治疗胃底静脉曲张出血的疗效和安全性。方法:回顾性分析在2010年1月至2018年4月间接受联合BRTOcc治疗的急性胃底静脉曲张出血患者的资料,包括患者人口统计资料、临床/内镜特征、治疗情况、治疗相关的不良事件及临床结局。结果:30例患者纳入研究,其中女性13例(43.3%),中位年龄58(范围:25-29)岁。按Sarin分类,食管胃底静脉曲张(2型)16例(53.3%),单纯胃底静脉曲张(1型)14例(46.7%)。中位临床随访时间151(范围:4-2,513)天,中位内镜随访时间98(范围:3-2,373)天。中位氰基丙烯酸酯/碘油注射量7(范围:4-22)mL。3例(10.0%)患者出现手术相关的不良事件,包括短暂发热、轻度肺栓塞和注射部位溃疡出血。内镜随访发现,21例患者中18例(85.7%)胃底静脉曲张完全闭塞;1例(3.3%)患者发生延迟的静脉曲张再出血,另2例(6.7%)疑似发生再出血。尽管未出现手术相关的死亡,但总体病死率高达46.7%,主要是死于肝病进展及合并症。结论:对于胃底静脉曲张出血, 内镜下注射联合BRTOcc是一种相对安全有效的治疗方法, 可获得比较高的静脉曲张闭塞率, 同时严重不良事件发生率较低。 | Fateh Bazerbachi Akira Dobashi Swarup Kumar Sanjay Misra Navtej S.Buttar Louis M.Wong Kee Song | 2021 | Gastroenterology Report2021，9，3： | 0 |
| 19 | 减重手术可使肝硬化患者长期受益显示文摘背景:肥胖常见于肝硬化患者,特别是非酒精性脂肪性肝炎(NASH)越来越流行之后。考虑到较高的围手术期风险,临床上会尽量避免对这些患者进行减重手术,因此,其长期疗效的数据仍然缺乏。本研究旨在评估减重手术对肝硬化患者中的长期疗效。方法:我们对2009年2月23日至2011年11月9日间开展的一项初步研究的病例资料进行回顾性分析,包括肝病情况、代谢状态及生存结果。该研究前瞻性地纳入接受减肥手术的代偿性肝硬化成人患者并对其进行随访。本研究对其中随访记录超过4年的患者进行描述性分析,以评估减肥手术的长期疗效。结果:全组共10例患者,其中女性7例。术后平均随访时间8.7-1.4年。所有患者均患有病理证实的NASH;2位患者并发未经治疗的丙型肝炎。随访期间,患者体重平均下降24 kg(相对于术前体重下降19.2%,P<0.001),仅1例患者重回术前水平。1例不宜肝移植的患者术后3年发生肝性脑病,随即去世;其余9例患者未发生肝性脑病、心血管事件或死亡。末次随访时,除1例吉尔伯特综合征患者之外,其余8例胆红素水平均在正常范围内。结论:减肥手术应用于使代偿性肝硬化患者,不仅可获得长期的减重效果,而且能保持稳定的肝功能。 | Manhal Izzy Mounika Angirekula Barham KAbu Dayyeh Fateh Bazerbachi Kymberly D.Watt | 2021 | Gastroenterology Report2021，9，3： | 0 |
| 20 | 戊型肝炎病毒感染的肝外表现:文献综述显示文摘背景与目的:戊型肝炎病毒(HEV)感染是威胁公众健康的一个重要问题,每年受感染人数约2千万,其中250万人出现急性肝损伤,56000人死亡。与其他病毒性肝炎一样,肝外表现是该病的一个重要特征。急性腺胰炎、神经系统、肌肉骨骼系统、血液系统、肾脏及其他免疫调节疾病作为HEV肝外表现已有过报道,而且仍然不时有新的肝外表现被发现。本文旨在全面综述HEV感染肝外表现的相关文献。数据收集:以MeSH主题词“hepatitis E”和每一项HEV相关的肝外表现作为关键词,在PubMed数据库中进行检索,不设置任何语种或资料限制。并通过纳入文献的文后参考文献列表追加检索。结果:既往文献曾报道过多种与HEV感染相关的肝外表现,其中一些肝外表现与HEV感染之间存在相关性,而且排除了这些肝外表现的其他可能病因,提示HEV可引起这些肝外表现。根据现有的数据,HEV感染似乎与急性胰腺炎、神经系统疾病(原发性外周支配神经受累,最常见的是继发于神经痛性肌萎缩的Guillain-Barre综合征)、血液系统疾病(磷酸葡萄糖脱氢酶缺乏引起的溶血性贫血和严重的血小板减少症)、肾小球肾炎及混合型冷球蛋白血症等疾病密切相关。而HEV感染是否与肌肉骨骼系统或其他免疫调节疾病具有相关性尚需更多数据证实。结论:对于急性胰腺炎、Guillain-Barre综合征、神经痛性肌萎缩、磷酸葡萄糖脱氢酶缺乏引起的溶血性贫血、严重血小板减少症、肾小球肾炎或混合型冷球蛋白血症患者,应考虑HEV感染的可能。同时,对于急性或慢性HEV感染者,也应留意上述肝外疾病的症状和体征。而对于HEV在其他肝外疾病中的作用尚需更多数据证实。 | Fateh Bazerbachi Samir Haffar Sushil K Garg John R Lake | 2016 | Gastroenterology Report2016，4，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员