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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Combined evaluation of a panel of protein and miRNA serum‐exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity显示文摘 | Bindhu Madhavan Shijing Yue Uwe Galli Sanyukta Rana Wolfgang Gross Miryam Müller Nathalia A. Giese Holger Kalthoff Thomas Becker Markus W Büchler Margot Z?ller | 2015 | Int. J. Cancer2015，，11： | 2 |
| 3 | Oscillatory Motions Sunspots 显示文摘 | Beckers J M Schuhz R B | 1972 | Solar Physics1972，27，1： | 1 |
| 4 | CT of coronary artery disease显示文摘 | SCHOEPF U J BECKER C R OHNESORGE B M | 2004 | Radiology2004，23，1： | 1 |
| 5 | Constitutive modeling of viscoelastic materials with damage: Computational aspects 显示文摘 | Conga M E Becker E B Ozupek S | 2001 | Computer Methods in Applied Mechanics and Engineering2001，190，1517： | 1 |
| 6 | Strategic human resource management : where do we go from here? 显示文摘 | Becker B E Huselid M A | 2006 | Journal of Management2006，，32： | 1 |
| 7 | Extravasation of radiographic contrast is an independent predictor of death in primary intracerebral hemorrhage显示文摘 | Becker K J Baxter A B Bybee H M | 1999 | Stroke1999，30，10： | 1 |
| 8 | Human follicle- stimulating hormone beta -subunit gene encodes multiple messenger ribonucleic acids显示文摘 | Jameson J L Becker C B Lindell C M | 1958 | Mol Endocrinol1958，2，9： | 1 |
| 9 | Middle east respiratory syndrome eoronavirus spike protein delivered by modified vaccinia virus ankara effi- ciently induces virus-neutralizing antibodies显示文摘 | Song F Fux R Provacia L B Volz A Eickmann M Becker S Osterhaus A D Haagmans B L Sutter G | 2013 | J Vir ol2013，87，11： | 1 |
| 10 | Detection of differentially regulated genes in keratinocytes by cDNA array hybridization:Hsp27 and other novel players in response to artificial ultraviolet radiation显示文摘 | Becker B Vogt T Landthaler M | 2001 | J Invest Dermatol2001，116，6： | 1 |
| 11 | The PULSE initiative: scientific priorities and strategic planning for resuscitation research and life saving therapies 显示文摘 | Becker L B Weisfeldt M L Weil M H | 2002 | Circulation2002，105，21： | 1 |
| 12 | Separate effects of ischemia and reperfusion on vascular permeability in ventilated ferret lungs显示文摘 | Becker P M Pearse D B Permutt S etal | 1992 | J Appl Physiol1992，73，6： | 1 |
| 13 | The relationship of breast-feeding, overweight and asthma in preadolescents 显示文摘 | Mai X M Becker A B Sellers E A | 2007 | Allergy Clin Immunol2007，120，3： | 1 |
| 14 | Emergency medical services in the reconstruction phase following a major earthquake: A case study of the 1988 Armenia earthquake显示文摘 | Handrlgan M T Becker B M Jagminas L | 1998 | Prehospital Disaster Med1998，13，1： | 1 |
| 15 | Dis- ordered calcium homeostasis of sepsis: association with calcitonin precursors 显示文摘 | MULLER B BECKER K L KRANZLIN M | 2000 | Eur J Clin Invest2000，30，9： | 1 |
| 16 | Evaluation of candidate vaccine approaches for mers-cov显示文摘 | Wang L Shi W Joyce M G Modjarrad K Zhang Y Leung K Lees C R Zhou T Yassine H M KanekiyoM Yang Z Y Chen X Becker M M Freeman M Vogel L Johnson J C Olinger G Todd J P Bagci U Solomon J Mollura D J Hensley L Jahrling P Deni- son M R Rao S S Subbarao K Kwong P D Mascola J R Kong W P Graham B S | 2015 | Nat Commun2015，6，： | 1 |
| 17 | Tracking of leukocyte recruitment into tissues of mice by in situlabbeling of blood cells with the fluorescent dye CFDA-SE显示文摘 | BECKER H M CHEN M HAY J B | 2004 | J Immunol Methods2004，286，12： | 1 |
| 18 | Coaxial electromagnetic launcher calculations using FE-BE method and Hybrid Potentials 显示文摘 | Chang J H Becker E B Driga M D | 1993 | IEEETransaon Magnetics1993，29，1： | 1 |
| 19 | Multislice helical CT of the heart with retrospective ECG gating: reduction of radiation exposure by ECG-controlled tube current modulation显示文摘 | Jakobs T F Becker C R Ohnesorge B M | 2002 | Eur Radial2002，12，： | 1 |
| 20 | Numerical simulation for induction coil launcher using FE-BE method with hybrid potentials显示文摘 | Chang J H Becker E B Driga M D | 1995 | IEEE Transactions on Magnetics1995，31，3： | 1 |
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