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| 1 | Trans-arterial chemoperfusion for the treatment of liver metastases of breast cancer and colorectal cancer: Clinical results in palliative care patients显示文摘AIM To evaluate the clinical value and efficiency of transarterial chemoperfusion(TACP) in patients with liver metastases from breast cancer(BC) and colorectal cancer(CRC).METHODS We treated 36 patients with liver metastases of BC(n = 19, 19 females) and CRC(n = 17; 8 females, 9 males) with repeated TACP. The treatment interval was 4 wk. TACP was performed with gemcitabine(1000 mg/m2) and mitomycin(10 mg/m2), administered within 1 h after positioning the catheter tip in the hepatic artery. Before treatment, the size, location, tumour volume, vascularization and number of liver tumours were evaluated using magnetic resonance imaging(MRI). Tumour response was evaluated according to the Response Evaluation Criteria in Solid Tumors guidelines.RESULTS TACP using gemcitabine and mitomycin for metastases from CRC and BC was performed without any serious side effects. The follow-up MRI showed a therapeutic response in 84.2% of the BC patients-stable disease 47.4% and partial response 36.8%. A progression was seen in 15.8%.CRC patients showed a therapeutic response in 52.9% of cases. A progression of the disease was documented in 47.1% of the patients with CRC. These data show that TACP in patients with liver metastases of BC leads to a significantly better therapeutic response compared with CRC patients(P = 0.042). The median survival time was 13.2 mo for the BC patients, which is significantly longer than for CRC patients at 9.3 mo(P = 0.001).CONCLUSION TACP for liver metastases of BC appears to be a safe and effective palliative treatment with improved outcomes in comparison to patients with CRC. | Tatjana Gruber-Rouh Marcel Langenbach Nagy NN Naguib Nour-Eldin M Nour-Eldin Thomas J Vogl Stephan Zangos Martin Beeres | 2017 | World Journal of Clinical Oncology2017，8，4： | 7 |
| 2 | 查看详情显示文摘 | Derbyshire F J De Beer V H J Abotsi G M K Scaroni A W, Solar J M, Skrovanek D J | | 0，，： | 2 |
| 3 | The relation between morphology and hydrotreating activity for supported MoS2 particles 显示文摘 | HENSEN E J M KOOYMAN P J Van der MEER Y Van der KRAAN A M de BEER V H J Van VEEN J A R Van SANTEN R A | 2001 | J Catal2001，199，2： | 1 |
| 4 | Efficient evaluation of integrals of order using Gauss quadrature显示文摘 | Jun L Beer G Meek J L | 1985 | Engng Anal1985，2，： | 1 |
| 5 | Quantitative real- time PCR assay for determining transgene copy num- ber in transformed plants 显示文摘 | Ingham D J Beer S Money S | 2001 | Bioteehniques2001，31，1： | 1 |
| 6 | Cholesteryl ester transfer protein and groupIIa secretory phospholipase A2 liberate bioactive serum amyloid A from HDL 显示文摘 | Jahangiri A Witta J de Beer MC | 2006 | Arteriascler Thromb Vasc Biol2006，26，5： | 1 |
| 7 | galacto-RGD positron emission tomography for imaging of alphavbeta3 expression on the neovasculature in patients with squamous cell carcinoma of the head and neck显示文摘 | Beer AJ Grosu AL Carlsen J | 2007 | Clin Cancer Res2007，13，221： | 1 |
| 8 | Combustion in Swirling Flows: A Review 显示文摘 | Syred N Beer J M | 1974 | Combustion and Flame1974，23，2： | 1 |
| 9 | Bandaging technique after knee replacement显示文摘 | Charalambides C Beer M Melhuish J | 2005 | Acta Orthop2005，76，1： | 1 |
| 10 | Persistent solar influence on North Atlantic climate during the Holocene 显示文摘 | Bond G Kromer b Beer J | 2001 | Science2001，294，： | 1 |
| 11 | HDL modification by secretory phospholipase A(2) promotes scavenger receptor class B type I interaction and accelerates HDL catabolism 显示文摘 | de Beer PC Connell PM Yu J | 2000 | J Lipid Res2000，41，11： | 1 |
| 12 | An investigation into the influence of longitudinal creepage on railway squeal noise due to lateral creepage显示文摘 | Monk-Steel A D Thompson D J De Beer F G | 2006 | Journal of Sound and Vibration2006，293，35： | 1 |
| 13 | Effects of metals on growth, morphology and reproduction of Ceratodon purpureus显示文摘 | Shaw J Jules E S Beer S C | 1991 | The Bryologist1991，94，3： | 1 |
| 14 | Effect of commercial processing on antioxidants in rice bran显示文摘 | LLOYD B J SIEBENMORGEN T J BEERS K W | 2000 | Cereal Chemistry2000，77，5： | 1 |
| 15 | Bandaging technique after knee replacement显示文摘 | Charalambides C Beer M Melhuish J | 2005 | Acta Orthop2005，76，1： | 1 |
| 16 | On the rate of combustion of soot in a laminar soot flame显示文摘 | LEE K B THRING M W BEER J M | 1962 | Combust Flame1962，6，： | 1 |
| 17 | Role of chance observations in chemotherapy : Vincarosea 显示文摘 | Noble R L Beer C T Cutts J H | 1958 | Ann N Y Acda Sci1958，76，3： | 1 |
| 18 | Carbon-supported sulfide catalysts显示文摘 | DUCHET J C Van OERS E M De BEER V H J PRINS R | 1983 | J Catal1983，80，2： | 1 |
| 19 | Extremely Metal-poor Stars II:Elemental Abundances and the Early Chemical Enrichment of the Galaxy显示文摘 | RYAN S G NORRIS J E BEERS T C | 1996 | ApJ1996，471，： | 1 |
| 20 | Fouling of Convection Heat Exchangers by Lignitic Coal Ash 显示文摘 | Walsh P M Sarofim A F Beer J M | 1992 | Energy & Fuels1992，6，6： | 1 |
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