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| 1 | Current practice of anticoagulant in the treatment of splanchnic vein thrombosis secondary to acute pancreatitis显示文摘Background:Severe acute pancreatitis is a common diagnosis in emergency general surgery and can be a cause of significant morbidity and mortality.A consequence of severe acute pancreatitis is thrombus in the splanchnic veins.These thrombi can potentially lead to bowel ischemia or hepatic failure.However,another complication of severe acute pancreatitis is retroperitoneal bleeding.At this time,it is unclear if treating patients for splanchnic vein thrombosis in the context of severe acute pancreatitis is associated with any outcome benefit.A systematic review might clarify this question.Data sources:A two-fold search strategy(one broad and one precise)looked at all published literature.The review was registered on PROSPERO(ID:CRD42018102705).MEDLINE,EMBASE,PubMed,Cochrane and Web of Science databases were searched and potentially relevant papers were reviewed indepen-dently by two researchers.Any disagreement was reviewed by a third independent researcher.Primary outcome was reestablishment of flow in the thrombosed vein versus bleeding complications.Results:Of 1462 papers assessed,a total of 16 papers were eligible for inclusion.There were no ran-domized controlled trials,2 were case series,5 retrospective single-center studies and 9 case reports.There were a total of 198 patients in these studies of whom 92(46.5%)received anticoagulation therapy.The rates of recanalization of veins in the treated and non-treated groups was 14%and 11%and bleeding complications were 16%and 5%,respectively.However,the included studies were too heterogeneous to undertake a meta-analysis.Conclusions:The systematic review highlights the lack evidence addressing this clinical question.There-fore a randomized controlled trial would be appropriate to undertake. | William Norton Gabija Lazaraviciute George Ramsay Irene Kreis Irfan Ahmed Mohamed Bekheit | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，2： | 8 |
| 2 | Transit time ultrasound perivascular flow probe technology is superior to MR imaging on hepatic blood flow measurement in a porcine model显示文摘Background: The hepatic hemodynamics is an essential parameter in surgical planning as well as in various disease processes. The transit time ultrasound(TTUS) perivascular flow probe technology is widely used in clinical practice to evaluate the hepatic inflow, yet invasive. The phase-contrast-MRI(PC-MRI) is not invasive and potentially applicable in assessing the hepatic blood flow. In the present study, we compared the hepatic inflow rates using the PC-MRI and the TTUS probe, and evaluated their predictive value of post-hepatectomy adverse events. Methods: Eighteen large white pigs were anaesthetized for PC-MRI and approximately 75% hepatic resection was performed under a unified protocol. The blood flow was measured in the hepatic artery(Qha), the portal vein(Qpv), and the aorta above the celiac trunk(Qca) using PC-MRI, and was compared to the TTUS probe. The Bland-Altman method was conducted and a partial least squares regression(PLS) model was implemented. Results: The mean Qpv measured in PC-MRI was 0.55 ± 0.12 L/min, and in the TTUS probe was 0.74 ± 0.17 L/min. Qca was 1.40 ± 0.47 L/min in the PC-MRI and 2.00 ± 0.60 L/min in the TTUS probe. Qha was 0.17 ± 0.10 L/min in the PC-MRI, and 0.13 ± 0.06 L/min in the TTUS probe. The Bland-Altman method revealed that the estimated bias of Qca in the PC-MRI was 32%(95% CI:-49% to 15%); Qha 17%(95% CI:-15% to 51%); and Qpv 40%(95% CI:-62% to 18%). The TTUS probe had a higher weight in predicting adverse outcomes after 75% resection compared to the PC-MRI( β= 0.35 and 0.43 vs β = 0.22 and 0.07, for tissue changes and premature death, respectively). Conclusions: There is a tendency of the PC-MRI to underestimate the flow measured by the TTUS probes. The TTUS probe measures are more predictive of relevant post-hepatectomy outcomes. | Mohamed Bekheit Chloe Audebert Petru Bucur Hans Adriaensen Emilie Bled Mylène Wartenberg Irene Vignon-Clementel Eric Vibert | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，6： | 3 |
| 3 | The role of graft reperfusion sequence in the development of non-anastomotic biliary strictures following orthotopic liver transplantation: A meta-analysis显示文摘Background: Liver transplant is a potential cure for liver failure and hepatic malignancy but there are many techniques which have been described for vascular reconstruction. This study was to compare the prevalence of non-anastomotic biliary stricture and other surgical complications based on Clavien-Dindo scoring system, in initial portal reperfusion(sequential) versus simultaneous or initial artery reperfusion. Data sources: Meta-analysis of published studies comparing the outcomes of both techniques was carried out. Data search was conducted across the major databases and studies were selected under the guidance of the Cochrane guidelines for systematic reviews and meta-analysis. Results: Seven studies were included to address the primary and the secondary outcomes. No statistical difference was found in the incidence of non-anastomotic biliary strictures(OR = 0.40; P = 0.14), regardless of reperfusion technique. The pooled estimate of the Clavien-Dindo grading of complications was not significantly different between the techniques, though Clavien-Dindo II complications were higher in the simultaneous or initial artery reperfusion group than the initial portal reperfusion group(OR = 2.73; P = 0.01). Similarly, there was no difference in the operative time, hospital stay and other outcomes addressed in this report. Conclusions: The available evidence suggests that there is no significant difference demonstrated in the rate of non-anastomotic biliary strictures or other complications, between the two techniques, except for Clavien-Dindo II complications. | Mohamed Bekheit Matteo Catanzano Stuart Shand Irfan Ahmed ELSaid ELKayal Gihan Mohamed Shehata Adel Zaki | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 2 |
| 4 | Synthesis, spectroscopic characterization and antimicrobial studies of some metal complexes with 2-acetylpyridine phenoxyacetyl hydrazone (HAPPA)显示文摘 | Magdy M. Bekheit Amira R. El-Shobaky Mohamed T. Gad Allah | 2013 | Arabian Journal of Chemistry2013，，： | 1 |
| 5 | el-Sakr A, Rasheed Q, Craelius W, el-sherif N Use of heartrete spectral analysis to study the effect of calcium channel blockers on sympatheticactivity after my ocardial infarction显示文摘 | Bekheit S Tangella M | 1990 | Am Heart J1990，119，： | 1 |
| 6 | Theory of coupled resonator microwave bandpass filters of arbitrary bandwidth 显示文摘 | AMARI S SEYFERT F BEKHEIT M | 2010 | IEEE Transactions on Microwave Theory and Techniques2010，58，8： | 1 |
| 7 | Development of an enzyme-linked immunosorbent assay for the β-exotoxin of Bacillus thuringiensis显示文摘 | Bekheit H K Lucas A D Gee S J | 1993 | J Agric Food Chem1993，41，9： | 1 |
| 8 | Novel pandemic A ( H1N1 ) influenza vaccination among pregnant women : motivators and barriers显示文摘 | Steelfisher GK Blendon RJ Bekheit MM | 2011 | Am J Obstet Gynecol2011，204，61： | 1 |
| 9 | A direct design technique for dual mode inline microwave bandpass filters显示文摘 | Bekheit M Amari S | 2009 | IEEE Transactions on Microwave Theory and Techniques2009，57，9： | 1 |
| 10 | Synthesis of Hapten and Conjugates for Enzyme Immunoassay for Analysis of the Herbicide Vromacil显示文摘 | SZURDOKI F BEKHEIT H K M MARCO M P | 1992 | J Agric Food Chem1992，40，： | 1 |
| 11 | Use of heart rete spectral analysis for study the effects of calcium channel blockers on sympathetic activity after myocardial infarction显示文摘 | Bekheit S Tanglla M Elsaki A | 1990 | Am Heart J1990，119，1： | 1 |
| 12 | Post-hepatectomy liver failure:A timeline centered review显示文摘Background: Post-hepatectomy liver failure(PHLF) is a leading cause of postoperative mortality after liver surgery. Due to its significant impact, it is imperative to understand the risk stratification and preventative strategies for PHLF. The main objective of this review is to highlight the role of these strategies in a timeline centered way around curative resection. Data sources: This review includes studies on both humans and animals, where they addressed PHLF. A literature search was conducted across the Cochrane Library, Embase, MEDLINE/Pub Med, and Web of Knowledge electronic databases for English language studies published between July 1997 and June 2020. Studies presented in other languages were equally considered. The quality of included publications was assessed using Downs and Black’s checklist. The results were presented in qualitative summaries owing to the lack of studies qualifying for quantitative analysis. Results: This systematic review with 245 studies, provides insight into the current prediction, prevention, diagnosis, and management options for PHLF. This review highlighted that liver volume manipulation is the most frequently studied preventive measure against PHLF in clinical practice, with modest improvement in the treatment strategies over the past decade. Conclusions: Remnant liver volume manipulation is the most consistent preventive measure against PHLF. | Mohamed Bekheit Lisa Grundy Ahmed KA Salih Petru Bucur Eric Vibert Mudassar Ghazanfar | 2023 | Hepatobiliary & Pancreatic Diseases International2023，22，6： | 1 |
| 13 | Use of intracardiac echocar- diography for early detection of phrenic nerve injury during cryobal- loon pulmonary vein isolation 显示文摘 | Lakhani M Saiful F Bekheit S | 2012 | J Cardiovasc Electrophysiol2012，23，： | 1 |
| 14 | Synthesis and structure studies of complexes of some second row transition merals with 1 - (phenylacetyl and Phenoxyacetyl ) -4 - phenyl - 3 -thiosemicarbazide显示文摘 | Sahar I Mostafa Magdy M Bekheit | 2000 | Chem Pharm BuU2000，48，2： | 1 |
| 15 | Modeling and oplimization of compact microwave bandpass fil ters显示文摘 | BEKHEIT M AMARI S MENZEL W | 2008 | IEEETrans Microw Theory Tech2008，56，2： | 1 |
| 16 | Synthesis of some transition metal complexes derived from valeroy1-4-pheny1-3-thiosemicarbazide显示文摘 | Bekheit M M Ibrahim K M | 1986 | Synth React Inorg Met-org Chem1986，16，： | 1 |
| 17 | Physical interpretation and implications of similarity transformations in cou- pled resonator filter design显示文摘 | AMARI S BEKHEIT M | 2007 | IEEE Trans Mierow Theory Tech2007，55，7： | 1 |
| 18 | Synthesis of some transition metal complexes derived from valeroyl-4-phenyl-3-thiosemiearbazide 显示文摘 | Bekheit M M Ibrahim K M | 1986 | Synth React Inorg Met-org Chem1986，16，： | 1 |
| 19 | Synthesis of Some Transition Metal Complexes Derived from Valeroy1-4-pheny1-3-thiosemicarbazide显示文摘 | BEKHEIT M M IBRAHIM K M | 1986 | Synth React Inorg Met-org Chem1986，16，： | 1 |
| 20 | Serial volumetric ssessment of large for size liver grafts after whole :adaveric liver transplant in adults: do large liver grafts shrink in size?显示文摘 | Bekheit M Rajakannu M Bucur P | 2016 | HPB (Oxford)2016，18，2： | 1 |
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