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| 1 | Impact of medical therapies on inflammatory bowel disease complication rate显示文摘Crohn's disease and ulcerative colitis are progressive diseases associated with a high risk of complications over time including strictures,fistulae,perianal complications,surgery,and colorectal cancer.Changing the natural history and avoiding evolution to a disabling disease should be the main goal of treatment.In recent studies,mucosal healing has been associated with longer-term remission and fewer complications.Conventional therapies with immunosuppressive drugs are able to induce mucosal healing in a minority of cases but their impact on disease progression appears modest.Higher rates of mucosal healing can be achieved with anti-tumor necrosis factor therapies that reduce the risk of relapse,surgery and hospitalization,and are associated with perianal fistulae closure.These drugs might be able to change the natural history of the disease mainly when introduced early in the course of the disease.Treatment strategy in inflammatory bowel diseases should thus be tailored according to the risk that each patient could develop disabling disease. | Catherine Reenaers Jacques Belaiche Edouard Louis | 2012 | World Journal of Gastroenterology2012，18，29： | 4 |
| 2 | Biomarker discovery for inflammatory bowel disease, using proteomic serum profiling显示文摘 | Marie-Alice Meuwis Marianne Fillet Pierre Geurts Dominique de Seny Laurence Lutteri Jean-Paul Chapelle Vincent Bours Louis Wehenkel Jacques Belaiche Michel Malaise Edouard Louis Marie-Paule Merville | 2007 | Biochemical Pharmacology2007，，9： | 2 |
| 3 | Adult human cytokeratin 19-positive cells recxpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans 显示文摘 | Kerr Conte J Belaich S | 2000 | Diabetes2000，49，10： | 1 |
| 4 | The Fibroscan:a new non invasive method of liver fibrosis evaluation显示文摘 | LAMPROYE A BELAICHE J DELWAIDE J | 2007 | Rev Med Liege2007，62，： | 1 |
| 5 | Elevated plasma citrulline: look for dihydrolipoamide dehydrogenase deficiency 显示文摘 | Haviv R Zeharia A Belaiche C | 2014 | Eur J Pediatr2014，173，2： | 1 |
| 6 | Guillain-Barrésyndrome following hepatitis E显示文摘Guillain-Barrésyndrome(GBS)is often triggered by a preceding bacterial or viral infection.Occasionally,it has been observed in association with acute hepatitis A,B and C,and three cases have been previously described in India in which GBS was associated with acute hepatitis E.A molecular mimicry mechanism is supposed to be involved in the pathogenesis of GBS triggered by infectious agents,although the nature of the shared epitopes has not been characterized in most instances,including that in the case of hepatotropic viruses.We report a case of GBS following acute hepatitis E in a European individual.The presence of antiganglioside GM2 antibodies in this patient suggested molecular mimicry involving ganglioside GM2 in the pathogenesis of GBS associated with hepatitis E. | Jean Philippe Loly Estelle Rikir Maxime Seivert Emile Legros Pierre Defrance Jacques Belaiche Gustave Moonen Jean Delwaide | 2009 | World Journal of Gastroenterology2009，15，13： | 1 |
| 7 | 5'-AZA induces Ngn3 expression and endocrine differentiation in the PANC-1 human ductal cell line显示文摘 | Lefebvre B Belaich S Lengue J | 2010 | Biochem Biophys Res Commun2010，391，1： | 1 |
| 8 | Longitudinal melanonychia in children: a clinical and histopathologic study of 40 cases 显示文摘 | Goettmann-Bonvallot S Andre J Belaich S | 1999 | J Am Acad Dermatol1999，41，1： | 1 |
| 9 | Beneficial effect of 1,25 dihydroxyvitamin D3 on cytokine-treated human pancreatic islets显示文摘 | Riachy R Vandewalle B Belaich S | 2001 | J Endocrinol2001，169，1： | 1 |
| 10 | Head and neck manifesta-tion and prognosis of Langerhans cell histiocytosis in children显示文摘 | Nicollas R Rome A Belaich H | | 0，，06： | 1 |
| 11 | Isolation and char- acterization of a high molecular weight antibiotic produced by a marine bacterium显示文摘 | Ballester M Ballester J M Belaich J P | 1977 | Microbial Ecology1977，3，4： | 1 |
| 12 | Idiopathic eruptive macular pigmentation (author's transl)显示文摘 | Degos R Civatte J Belaich S | 1978 | Ann Dermatol Venereol1978，105，2： | 1 |
| 13 | Head and neck manifestation and prognosis of Langerhans' cell histiocy-tosis in children显示文摘 | Nicollas R Rome A Belaich H | | 0，，： | 1 |
| 14 | Acute pancreatitis associated with atorvastatin therapy显示文摘 | Belaiche G Ley G Slama JL | | Gastroenterol Clin Biol0，24，4： | 1 |
| 15 | Acute pancreatitis associated with atorvastatine therapy 显示文摘 | Belaiche G Ley G Slama JL | 2000 | Gastroenterol Clin Biol2000，24，4： | 1 |
| 16 | The FibroScan:a new non-invasive method of hver fibrosis evaluation显示文摘 | Lamproye A Belaiche J Delwaide J | 2007 | Rev Med Liege2007，62，： | 1 |
| 17 | Beneficial effect of 1, 25 dihydroxyvitamin D3 on cytokine - treated human pancreatic islets 显示文摘 | Riachy R Vandewalle B Belaich S | 2001 | JEndocrinol2001，169，1： | 1 |
| 18 | Rapid detection of enterovirus in clinical specimens using PCR and microwell capture hybridization assay显示文摘 | Andreoletti L Hober D Belaich S | 1996 | J Virol Methods1996，62，1： | 1 |
| 19 | Adult human cytokeratin 19 positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans 显示文摘 | Gmyr V Verr-loote J Belaich S | 2000 | Diabetes2000，49，10： | 1 |
| 20 | Acute lower gastrointesti, nal bleeding in Crohn's disease: characteristics of a unique series of 34 patients 显示文摘 | Belaiche J Louis E D'Haens G | 1999 | Am J Gastroenterol1999，94，8： | 1 |
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