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| 1 | Acute upper gastrointestinal bleeding caused by esophageal right bronchial artery fistula:A case report显示文摘BACKGROUND Fistula between the esophagus and bronchial artery is an extremely rare and potentially life-threatening cause of acute upper gastrointestinal bleeding.Here,we report a case of fistula formation between the esophagus and a nonaneurysmal right bronchial artery(RBA).CASE SUMMARY An 80-year-old woman with previous left pneumonectomy and recent placement of an uncovered self-expandable metallic stent for esophageal adenocarcinoma was admitted due to hematemesis.Emergent computed tomography showed indirect signs of fistulization between the esophagus and a nonaneurysmal RBA,in the absence of active bleeding.Endoscopy revealed the esophageal stent correctly placed and a moderate amount of red blood within the stomach,in the absence of active bleeding or tumor ingrowth/overgrowth.After prompt multidisciplinary evaluation,a step-up approach was planned.The bleeding was successfully controlled by esophageal restenting followed by RBA embolization.No signs of rebleeding were observed and the patient was discharged home with stable hemoglobin level on postoperative day 7.CONCLUSION This was a previously unreported case of an esophageal RBA fistula successfully managed by esophageal restenting followed by RBA embolization. | Alberto Martino Gaspare Oliva Francesco Paolo Zito Mattia Silvestre Raffaele Bennato Luigi Orsini Raffaella Niola Luigia Romano Giovanni Lombardi | 2021 | World Journal of Gastrointestinal Endoscopy2021，13，11： | 1 |
| 2 | Electrochemiluminescence immunoassay method underestimates cortisol suppression in ulcerative colitis patients treated with oral prednisone显示文摘AIM: To evaluate cortisolemia by using conventional electrochemiluminescence immunoassay(ECLIA) method compared to liquid chromatography-tandem mass spectrometry(LC-MS/MS) method in active ulcerative colitis(UC) patients treated with oral prednisone(PD). METHODS: Twenty patients(12 males) with acute relapse of UC started oral PD at a dose of 40 mg once a day, tapered of 10 mg every 2 wk. When a stable 2-wk daily dose of 30 mg was reached, blood samples for cortisol levels' measurement were drawn in the morning in fasting conditions to determine circulating cortisol by LC-MS/MS and ECLIA assay. RESULTS: Median interquartile range cortisolemia with ECLIA and LC-MS/MS method was 54.1(185.8) nmol/L and 32.1(124.0) nmol/L, respectively(P < 0.001). The within-patient median differences between the two methods was 23.2(40.6) nmol/L, with higher cortisol levels for the ECLIA method. The estimated geomet-ric mean ratio between methods was 1.85(95%CI: 2.39-1.43) considering all data or 1.58(95%CI: 2.30-1.09) considering only data above the limit of quantification(n = 12). The 95%CIs of the geometric mean ratio between methods confirm a statistically significant difference.CONCLUSION: Blood cortisol levels detected with ECLIA method seems to be higher than the ones measured by LC-MS/MS, indicating a possible overestimation of them in patients treated with PD. Therefore, the cortisol suppression in patients under treatment with oral PD should not be measured using ECLIA method. | Francesco Manguso Raffaele Bennato Giovanni Lombardi Assunta Viola Elisabetta Riccio Livio Cipolletta | 2014 | World Journal of Gastroenterology2014，20，31： | 1 |
| 3 | Involvement of mitochondrial activity in mediating ELF-EMF stimulatory effect on human sperm motility显示文摘 | Iorio Roberto Delle Monache Simona Bennato Francesca | 2011 | Bioelectromagnetics2011，32，1： | 1 |
| 4 | In-hospital mortality 111non-variceal upper gastroint estinal bleeding Forrest 1 patiettts显示文摘 | Manguso F Riccio E Bennato R | 2008 | Scand J Gastroenterol2008，43，12： | 1 |
| 5 | ELF-MF attenu- ates quercetin-induced apoptosis in K562 cells through modulating the expression of Bcl-2 family proteins显示文摘 | Brisdelli F Bennato F Bozzi A | 2014 | Mol Cell Biochem2014，397，1： | 1 |
| 6 | A life-threatening case of stenosing pill hypopharynx-oesophagitis cased by a tamsulosin capsule显示文摘 | D'Agostino L Manguso F Bennato R | 2004 | Digliver Dis2004，36，9： | 1 |
| 7 | Involvement of mitochondrial activity in mediating ELF-EMF stimulatory effect on human sperm motility显示文摘 | Iorio R Delle Monache S Bennato F | | 0，，： | 1 |
| 8 | MELD评分与肝细胞癌评定肝硬化食管静脉曲张出血患者短期死亡的风险因素 | Amitrano L. Guardascione M.A. Bennato R. 杨媛 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，10： | 0 |
| 9 | Massive bleeding from gastric submucosal arterial collaterals secondary to splenic artery thrombosis: A case report显示文摘BACKGROUND Gastric submucosal arterial collaterals(GSAC)secondary to splenic artery occlusion is an extraordinary rare and potentially life-threatening cause of acute upper gastrointestinal bleeding.Here,we report a case of massive bleeding from GSAC successfully treated by means of a multidisciplinary minimally invasive approach.CASE SUMMARY A 60-year-old non-cirrhotic gentleman with a history of arterial hypertension was admitted due to hematemesis.Emergent esophagogastroduodenoscopy revealed pulsating and tortuous varicose shaped submucosal vessels in the gastric fundus along with a small erosion overlying one of the vessels.In order to characterize the fundic lesion,pre-operative emergent computed tomography-angiography was performed showing splenic artery thrombosis(SAT)and tortuous arterial structures arising from the left gastric artery and the left gastroepiploic artery in the gastric fundus.GSAC was successfully treated by means of a minimally invasive step-up approach consisting in endoscopic clipping followed by transcatheter arterial embolization(TAE).CONCLUSION This was a previously unreported case of bleeding GSAC secondary to SAT successfully managed by means of a multidisciplinary minimally invasive approach consisting in endoscopic clipping for the luminal bleeding control followed by elective TAE for the definitive treatment. | Alberto Martino Marco Di Serafino Francesco Paolo Zito Franco Maglione Raffaele Bennato Luigi Orsini Alessandro Iacobelli Raffaella Niola Luigia Romano Giovanni Lombardi | 2022 | World Journal of Gastroenterology2022，28，37： | 0 |
| 10 | The role of computed tomography for the prediction of esophageal variceal bleeding:Current status and future perspectives显示文摘Esophageal variceal bleeding(EVB)is one of the most common and severe complications related to portal hypertension(PH).Despite marked advances in its management during the last three decades,EVB is still associated with significant morbidity and mortality.The risk of first EVB is related to the severity of both PH and liver disease,and to the size and endoscopic appearance of esophageal varices.Indeed,hepatic venous pressure gradient(HVPG)and esophagogastroduodenoscopy(EGD)are currently recognized as the“gold standard”and the diagnostic reference standard for the prediction of EVB,respectively.However,HVPG is an invasive,expensive,and technically complex procedure,not widely available in clinical practice,whereas EGD is mainly limited by its invasive nature.In this scenario,computed tomography(CT)has been recently proposed as a promising modality for the non-invasive prediction of EVB.Although CT is only a diagnostic modality,thus being not capable of supplanting EGD or HVPG in providing therapeutic and physiological data,it could potentially assist liver disease scores,HVPG,and EGD in a more effective prediction of EVB.However,to date,evidence concerning the role of CT in this setting is still lacking.Our review aimed to summarize and discuss the current evidence concerning the role of CT in predicting the risk of EVB. | Alberto Martino Lucio Amitrano Marianna Guardascione Marco Di Serafino Raffaele Bennato Rossana Martino Annalisa de Leone Luigi Orsini Luigia Romano Giovanni Lombardi | 2023 | World Journal of Gastrointestinal Endoscopy2023，15，12： | 0 |
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