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| 1 | Adult-to-adult living-donor liver transplantation: The experience of the Université catholique de Louvain显示文摘Background: Liver transplantation is the treatment for end-stage liver diseases and well-selected malignancies. The allograft shortage may be alleviated with living donation. The initial UCLouvain experience of adult living-donor liver transplantation(LDLT) is presented. Methods: A retrospective analysis of 64 adult-to-adult LDLTs performed at our institution between 1998 and 2016 was conducted. The median age of 29(45.3%) females and 35(54.7%) males was 50.2 years(interquartile range, IQR 32.9–57.5). Twenty-two(34.4%) recipients had no portal hypertension. Three(4.7%) patients had a benign and 33(51.6%) a malignant tumor [19(29.7%) hepatocellular cancer, 11(17.2%) secondary cancer and one(1.6%) each hemangioendothelioma, hepatoblastoma and embryonal liver sarcoma]. Median donor and recipient follow-ups were 93 months(IQR 41–159) and 39 months(22–91), respectively. Results: Right and left hemi-livers were implanted in 39(60.9%) and 25(39.1%) cases, respectively. Median weights of right-and left-liver were 810 g(IQR 730–940) and 454 g(IQR 394–534), respectively. Graft-to-recipient weight ratios(GRWRs) were 1.17%(right, IQR 0.98%-1.4%) and 0.77%(left, 0.59%-0.95%). One-and five-year patient survivals were 85% and 71%(right) vs. 84% and 58%(left), respectively. Oneand five-year graft survivals were 74% and 61%(right) vs. 76% and 53%(left), respectively. The patient and graft survival of right and left grafts and of very small( < 0.6%), small(0.6%–0.79%) and large( ≥0.8%) GRWR were similar. Survival of very small grafts was 86% and 86% at 3-and 12-month. No donor died while five(7.8%) developed a Clavien–Dindo complication IIIa, IIIb or IV. Recipient morbidity consisted mainly of biliary and vascular complications; three(4.7%) recipients developed a small-for-size syndrome according to the Kyushu criteria. Conclusions: Adult-to-adult LDLT is a demanding procedure that widens therapeutic possibilities of many hepatobiliary diseases. The donor procedure can be done safely with low morbidity. The recipient operation carries a major morbidity indicating an important learning curve. Shifting the risk from the donor to the recipient, by moving from the larger right-liver to the smaller left-liver grafts, should be further explored as this policy makes donor hepatectomy safer and may stimulate the development of transplant oncology. | Samuele Iesari Milton Eduardo Inostroza Nú?ez Juan Manuel Rico Juri Olga Ciccarelli Eliano Bonaccorsi-Riani Laurent Coubeau Pierre-Fran?ois Laterre Pierre Goffette Chantal De Reyck Beno?t Lengelé Pierre Gianello Jan Lerut | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，2： | 5 |
| 2 | Structure-property relationship of all-cellulose composites 显示文摘 | BENO J C ROGER H N MARK P S | 2009 | Comp Sci Tech2009，69，： | 1 |
| 3 | Endotoxin-induced hyperlactatemia results from decreased lactate clearance in hemodynamically stable rats显示文摘 | SEVERIN P N UHING M R BENO D W | 2002 | Crit Care Med2002，30，： | 1 |
| 4 | Endotoxin-induced hyperlactatemia results from decreased lactate clearance in hemodynamically stable rats显示文摘 | Severin P N Uhing M R Beno D W A | 2002 | Crit Care Med2002，30，11： | 1 |
| 5 | Structural characterization of novel cassava starches with low and high-amylose contents in comparison with other commercial sources显示文摘 | Agnès Rolland-Sabaté Teresa Sánchez Alain Buléon Paul Colonna Beno?t Jaillais Hernán Ceballos Dominique Dufour | 2011 | Food Hydrocolloids2011，，1： | 1 |
| 6 | Just noticeable differences in component concentrations modify the odor quality of a blending mixture显示文摘 | Le Berre E Beno N Ishii A | 2008 | Chemical Senses2008，33，4： | 1 |
| 7 | Anomalous origin of circumflex artery from right sinus of Valsalva:a rare cause of non-ST elevation syndrome显示文摘 | PAPADOPOULOS D P DALIANIS N BENOS I | 2007 | Int J Cardiol2007，114，： | 1 |
| 8 | Diesel exhaust exposure favors T H 2 cell recruitment in nonatopic subjects by differentially regulating chemokine production显示文摘 | Ying Chang Stéphanie Sénéchal Patricia de Nadai Cécile Chenivesse Jules Gilet Han Vorng Benjamin Legendre André-Bernard Tonnel Beno?t Wallaert Philippe Lassalle Anne Tsicopoulos | 2006 | The Journal of Allergy and Clinical Immunology2006，，2： | 1 |
| 9 | Structure-property relationship of all-cellulose composites 显示文摘 | Beno J C Roger H N Mark P S | 2009 | Comp Sci Tech2009，69，： | 1 |
| 10 | Fiscal policy and economic growth:empirical evidence from EU countries显示文摘 | Benos N | 2009 | 2009，，： | 1 |
| 11 | 60个新观点带你另眼看世界显示文摘它们中既有仍处于研究阶段的假设,也有尚未察觉的关联,还有已存在事实支撑但还未进行论证的主张……毕竟从灵光一现到范式形成的过程非常漫长;观点的建立与科研工作的开花结果都需要时间。植物会说话吗?雨水会引发火山喷发吗? | Marie Atteia Kheira Bettayeb Coline Buanic Thomas Cavaillé-Fol Anne Debroise Olivier Donnars Stéphane Fay Lise Gougis Coralie Hancok Román Ikonicoff Hugo Leroux Vincent Nouyrigat Alexandra Pihen Benoît Rey Yves Sciama Jean Baptiste Veyrieras 王隽(编译) 缪伶超(编译) | 2020 | 新发现2020，，9： | 0 |
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